ChemInform Abstract: One-Pot Synthesis of Quinazoline Derivatives via [2 + 2 + 2] Cascade Annulation of Diaryliodonium Salts and Two Nitriles.

ChemInform ◽  
2013 ◽  
Vol 44 (45) ◽  
pp. no-no
Author(s):  
Xiang Su ◽  
Chao Chen ◽  
Yong Wang ◽  
Junjie Chen ◽  
Zhenbang Lou ◽  
...  
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts ◽  
Quinazoline Derivatives

One-pot synthesis of quinazoline derivatives via [2+2+2] cascade annulation of diaryliodonium salts and two nitriles

2013 ◽  
Vol 49 (60) ◽  
pp. 6752 ◽  
Author(s):  
Xiang Su ◽  
Chao Chen ◽  
Yong Wang ◽  
Junjie Chen ◽  
Zhenbang Lou ◽  
...  
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts ◽  
Quinazoline Derivatives

One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
Bronsted Acids ◽  
One Pot ◽  
Benzyl Alcohols ◽  
Iodonium Salts ◽  
Efficient Approach ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

Synthesis of pyrazolo[1,5-c]quinazoline derivatives through the copper-catalyzed domino reaction of o-alkenyl aromatic isocyanides with diazo compounds

2020 ◽  
Vol 56 (55) ◽  
pp. 7665-7668 ◽  
Author(s):  
Lu Liu ◽  
Lei Li ◽  
Shukuan Mao ◽  
Xin Wang ◽  
Ming-Dong Zhou ◽  
...  
Keyword(s):  
Diazo Compounds ◽  
Domino Reaction ◽  
Reaction Conditions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

Various o-alkenyl aromatic isocyanides were prepared from readily available reactants for their double annulation with diazo compounds for a one-pot synthesis of pyrazolo[1,5-c]quinazolines under mild reaction conditions.

scholarly journals One-Pot Synthesis of Unsymmetric Diaryliodonium Salts from Iodine and Arenes

2017 ◽  
Vol 82 (22) ◽  
pp. 11909-11914 ◽  
Author(s):  
Erik Lindstedt ◽  
Marcus Reitti ◽  
Berit Olofsson
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

Copper-Catalyzed One-Pot Synthesis of Unsymmetrical Arylurea Derivatives via Tandem Reaction of Diaryliodonium Salts with N-Arylcyanamide

2014 ◽  
Vol 79 (17) ◽  
pp. 8156-8162 ◽  
Author(s):  
Pengfei Li ◽  
Guolin Cheng ◽  
Hong Zhang ◽  
Xianxiang Xu ◽  
Jingyuan Gao ◽  
...  
Keyword(s):  
Tandem Reaction ◽  
One Pot ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

scholarly journals An Efficient One-Pot Multicomponent Synthesis of Tetracyclic Quinazolino[4,3-b]quinazolines by Sequential C–N Bond Formation and Copper-Mediated Aerobic Oxidative Cyclization

Synlett ◽  
2018 ◽  
Vol 29 (13) ◽  
pp. 1717-1722 ◽  
Author(s):  
Manjula Alla ◽  
Gal Potuganti ◽  
Divakar Indukuri
Keyword(s):  
Bond Formation ◽  
Nitrogen Sources ◽  
Oxidative Cyclization ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Aerobic Conditions ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

An efficient one-pot synthesis of quinazolino[4,3-b]quinazoline derivatives has been accomplished, starting from 2-(2-bromo­phenyl)quinazolin-4(3H)-one, aldehydes, and various nitrogen sources under aerobic conditions. The multicomponent protocol is mediated by copper(I) salts and involves amination of 2-(2-bromophenyl)quinazolin-4(3H)-one, followed by condensation with the aldehyde and an oxidative cyclization to give the target compounds in moderate to good yields.

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