ChemInform Abstract: Applications of Asymmetric Organocatalysis in Medicinal Chemistry

ChemInform ◽  
2013 ◽  
Vol 44 (22) ◽  
pp. no-no
Author(s):  
Jose Aleman ◽  
Silvia Cabrera
Keyword(s):  
Medicinal Chemistry ◽  
Asymmetric Organocatalysis

Applications of asymmetric organocatalysis in medicinal chemistry

2013 ◽  
Vol 42 (2) ◽  
pp. 774-793 ◽  
Author(s):  
José Alemán ◽  
Silvia Cabrera
Keyword(s):  
Medicinal Chemistry ◽  
Asymmetric Organocatalysis

Asymmetric organocatalysis: an enabling technology for medicinal chemistry

2021 ◽  
Vol 50 (3) ◽  
pp. 1522-1586
Author(s):  
Bo Han ◽  
Xiang-Hong He ◽  
Yan-Qing Liu ◽  
Gu He ◽  
Cheng Peng ◽  
...  
Keyword(s):  
Medicinal Chemistry ◽  
Enabling Technology ◽  
Comprehensive Overview ◽  
Asymmetric Organocatalysis ◽  
Antiparasitic Agents

This review provides a comprehensive overview of the recent applications of organocatalytic strategies in pharmaceutical synthesis, with a focus on the preparation of antiviral, anticancer, neuroprotective, cardiovascular, antibacterial and antiparasitic agents.

scholarly journals Asymmetric Organocatalysis at the Service of Medicinal Chemistry

2014 ◽  
Vol 2014 ◽  
pp. 1-29 ◽  
Author(s):  
Alfredo Ricci
Keyword(s):  
Medicinal Chemistry ◽  
Industrial Scale ◽  
Different Types ◽  
Asymmetric Organocatalysis ◽  
Covalent Interactions

The application of the most representative and up-to-date examples of homogeneous asymmetric organocatalysis to the synthesis of molecules of interest in medicinal chemistry is reported. The use of different types of organocatalysts operative via noncovalent and covalent interactions is critically reviewed and the possibility of running some of these reactions on large or industrial scale is described. A comparison between the organo- and metal-catalysed methodologies is offered in several cases, thus highlighting the merits and drawbacks of these two complementary approaches to the obtainment of very popular on market drugs or of related key scaffolds.

An Advance In Medicinal Chemistry

1952 ◽  
Vol 8 (5) ◽  
pp. 81-84
Author(s):  
Howard A. Sumner
Keyword(s):  
Medicinal Chemistry
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