ChemInform Abstract: Synthetic Studies on α,α-Disubstituted Amino Acids Employing (2S,4R)-4-Hydroxyproline as the Chiral Pool: Preparation of Methyl O-Benzyl-2-(α-cyanomethyl)-D-tyrosinate and Dimethyl 2-(4-Hydroxybenzyl)-L-aspartate.

Ryohei Nagahara; Chihiro Hisa; Noriko Kojima; Naoshi Yamamoto; Toshio Honda

doi:10.1002/chin.201318189

ChemInform Abstract: Synthetic Studies on α,α-Disubstituted Amino Acids Employing (2S,4R)-4-Hydroxyproline as the Chiral Pool: Preparation of Methyl O-Benzyl-2-(α-cyanomethyl)-D-tyrosinate and Dimethyl 2-(4-Hydroxybenzyl)-L-aspartate.

ChemInform ◽

10.1002/chin.201318189 ◽

2013 ◽

Vol 44 (18) ◽

pp. no-no

Author(s):

Ryohei Nagahara ◽

Chihiro Hisa ◽

Noriko Kojima ◽

Naoshi Yamamoto ◽

Toshio Honda

Keyword(s):

Amino Acids ◽

Synthetic Studies ◽

Disubstituted Amino Acids

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Synthetic Studies on α,α-Disubstituted Amino Acids Employing (2S,4R)-4-Hydroxyproline as the Chiral Pool: Preparation of Methyl O-Benzyl-2-(α-cyanomethyl)-D-tyrosinate and Dimethyl 2-(4-hydroxybenzyl)-L-aspartate

Heterocycles ◽

10.3987/com-12-s(n)9 ◽

2012 ◽

Vol 86 (1) ◽

pp. 659 ◽

Cited By ~ 1

Author(s):

Toshio Honda ◽

Chihiro Hisa ◽

Noriko Kojima ◽

Naoshi Yamamoto ◽

Ryohei Nagahara

Keyword(s):

Amino Acids ◽

Synthetic Studies ◽

Disubstituted Amino Acids

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Free Radical-Mediated Tandem Reaction of Dehydroamino Acid Derivative with π-Allyl Palladium Complex: Synthesis of α,α-Disubstituted Amino Acids

Synlett ◽

10.1055/s-2004-815407 ◽

2004 ◽

pp. 540-542 ◽

Cited By ~ 3

Author(s):

Yoshiji Takemoto ◽

Hideto Miyabe ◽

Ryuta Asada ◽

Kazumasa Yoshida

Keyword(s):

Amino Acids ◽

Free Radical ◽

Acid Derivative ◽

Palladium Complex ◽

Tandem Reaction ◽

Dehydroamino Acid ◽

Disubstituted Amino Acids

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Synthesis and Evaluation of Chiral and Achiral α,α-Disubstituted Amino Acids as β-Sheet Stabilizing Factors

Understanding Biology Using Peptides ◽

10.1007/978-0-387-26575-9_260 ◽

2010 ◽

pp. 595-596

Author(s):

Jia Wang ◽

Robert P. Hammer

Keyword(s):

Amino Acids ◽

Stabilizing Factors ◽

Disubstituted Amino Acids ◽

Β Sheet

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An Efficient Method for Large-Scale Synthesis of Stereochemically Defined and Conformationally Constrained β-Substituted or α,β-Disubstituted Amino Acids

Peptides: The Wave of the Future ◽

10.1007/978-94-010-0464-0_7 ◽

2001 ◽

pp. 26-27

Author(s):

Xuejun Tang ◽

Vadim A. Soloshonok ◽

Victor J. Hruby

Keyword(s):

Amino Acids ◽

Efficient Method ◽

Large Scale ◽

Conformationally Constrained ◽

Large Scale Synthesis ◽

Disubstituted Amino Acids

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Synthesis of a series of “cationic”, orthogonally protected, α, α-disubstituted amino acids

American Peptide Symposia - Peptides Frontiers of Peptide Science ◽

10.1007/0-306-46862-x_141 ◽

2005 ◽

pp. 329-330

Author(s):

T. S. Yokum ◽

M. G. Bursavich ◽

S. A. Piha-Paul ◽

D. A. Hall ◽

M. L. McLaughlin

Keyword(s):

Amino Acids ◽

Disubstituted Amino Acids

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ChemInform Abstract: Synthetic Studies of N-Acetyl Derivatives of Amino Acids and Thiolactone Using Vilsmeier-Haack Reagent.

ChemInform ◽

10.1002/chin.199338214 ◽

2010 ◽

Vol 24 (38) ◽

pp. no-no

Author(s):

B. BALASUNDARAM ◽

M. VENUGOPAL ◽

P. T. PERUMAL

Keyword(s):

Amino Acids ◽

Synthetic Studies ◽

Derivatives Of

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Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures

Molecules ◽

10.3390/molecules23051099 ◽

2018 ◽

Vol 23 (5) ◽

pp. 1099 ◽

Cited By ~ 3

Author(s):

Yosuke Ota ◽

Taeko Kakizawa ◽

Yukihiro Itoh ◽

Takayoshi Suzuki

Keyword(s):

Amino Acids ◽

Histone H3 ◽

Design Synthesis ◽

In Vitro Evaluation ◽

Disubstituted Amino Acids

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Development of helix-stabilized cell-penetrating peptides containing cationic α,α-disubstituted amino acids as helical promoters

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.01.044 ◽

2017 ◽

Vol 25 (6) ◽

pp. 1846-1851 ◽

Cited By ~ 13

Author(s):

Hiroko Yamashita ◽

Takashi Misawa ◽

Makoto Oba ◽

Masakazu Tanaka ◽

Mikihiko Naito ◽

...

Keyword(s):

Amino Acids ◽

Cell Penetrating Peptides ◽

Cell Penetrating ◽

Disubstituted Amino Acids

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Iron-Catalyzed Synthesis of α,α-Disubstituted Amino Acids from Azlactones and Indoles

Synfacts ◽

10.1055/s-0040-1707331 ◽

2020 ◽

Vol 16 (08) ◽

pp. 0998

Keyword(s):

Amino Acids ◽

Disubstituted Amino Acids

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PEPTIDES CONTAINING ɑɑ-DISUBSTITUTED AMINO ACIDS. EXPERIMENTS RELATED TO ɑ-HYDROXYMETHYLSERINE

Porto Carras, Chalkidiki, Greece, Aug. 31–Sept. 5, 1986 ◽

10.1515/9783110864243-056 ◽

1987 ◽

pp. 251-254

Author(s):

K. Kociolek ◽

U. Slomczynska ◽

M.T. Leplawy

Keyword(s):

Amino Acids ◽

Disubstituted Amino Acids

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