ChemInform Abstract: MRI Paramagnetic Probes for Cellular Labeling

ChemInform ◽  
2012 ◽  
Vol 43 (29) ◽  
pp. no-no
Author(s):  
Eliana Gianolio ◽  
Rachele Stefania ◽  
Enza Di Gregorio ◽  
Silvio Aime
Keyword(s):  
Paramagnetic Probes ◽  
Cellular Labeling

MRI Paramagnetic Probes for Cellular Labeling

2012 ◽  
Vol 2012 (12) ◽  
pp. 1934-1944 ◽  
Author(s):  
Eliana Gianolio ◽  
Rachele Stefania ◽  
Enza Di Gregorio ◽  
Silvio Aime
Keyword(s):  
Paramagnetic Probes ◽  
Cellular Labeling

scholarly journals Mesenchymal Stem Cells Do Not Lose Direct Labels Including Iron Oxide Nanoparticles and DFO-89Zr Chelates through Secretion of Extracellular Vesicles

Membranes ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 484
Author(s):  
Yue Gao ◽  
Anna Jablonska ◽  
Chengyan Chu ◽  
Piotr Walczak ◽  
Miroslaw Janowski
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Extracellular Vesicles ◽  
Superparamagnetic Iron Oxide ◽  
Cell Labeling ◽  
Oxide Nanoparticles ◽  
Stem Cell Delivery ◽  
Cellular Labeling

Rapidly ageing populations are beset by tissue wear and damage. Stem cell-based regenerative medicine is considered a solution. Years of research point to two important aspects: (1) the use of cellular imaging to achieve sufficient precision of therapeutic intervention, and the fact that (2) many therapeutic actions are executed through extracellular vesicles (EV), released by stem cells. Therefore, there is an urgent need to interrogate cellular labels in the context of EV release. We studied clinically applicable cellular labels: superparamagnetic iron oxide nanoparticles (SPION), and radionuclide detectable by two main imaging modalities: MRI and PET. We have demonstrated effective stem cell labeling using both labels. Then, we obtained EVs from cell cultures and tested for the presence of cellular labels. We did not find either magnetic or radioactive labels in EVs. Therefore, we report that stem cells do not lose labels in released EVs, which indicates the reliability of stem cell magnetic and radioactive labeling, and that there is no interference of labels with EV content. In conclusion, we observed that direct cellular labeling seems to be an attractive approach to monitoring stem cell delivery, and that, importantly, labels neither locate in EVs nor affect their basic properties.

scholarly journals Synthesis and cellular labeling of multifunctional phosphatidylinositol bis‐ and trisphosphate derivatives

2021 ◽  
Author(s):  
Rainer Mueller ◽  
Ana Kojic ◽  
Mevlut Citir ◽  
Carsten Schultz
Keyword(s):  
Cellular Labeling

Curauá-derived carbon dots: Fluorescent probes for effective Fe(III) ion detection, cellular labeling and bioimaging

2021 ◽  
pp. 112409
Author(s):  
Sebastian Raja ◽  
Eva Miriam Buhl ◽  
Stephan Dreschers ◽  
Carmen Schalla ◽  
Martin Zenke ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Carbon Dots ◽  
Ion Detection ◽  
Cellular Labeling

EPR INVESTIGATIONS OF CuO-B2O3-PbO-Ag2O GLASSES

2009 ◽  
Vol 23 (05) ◽  
pp. 747-753
Author(s):  
VIOREL TIMAR ◽  
RALUCA CICEO-LUCÃCEL ◽  
OCTAVIA HULPUŞ ◽  
IOAN ARDELEAN
Keyword(s):  
Copper Content ◽  
Structural Modification ◽  
Magnetic Interactions ◽  
Paramagnetic Resonance ◽  
Distorted Octahedral ◽  
Structural Details ◽  
Paramagnetic Probes ◽  
Parallel Band ◽  
Electron Paramagnetic ◽  
Epr Experiments

Glasses of the x CuO · (100 - x)[3 B 2 O 3· 0.9 PbO · 0.1 Ag 2 O ] system, with 0.5 ≤ x ≤ 10 mol %, were prepared and investigated by means of electron paramagnetic resonance (EPR) measurements. Structural details of different diamagnetic vitreous systems may be revealed by the Cu 2+ ions, frequently used as paramagnetic probes in EPR experiments. The shape and the intensity of the recorded EPR lines are dependent on the CuO content. The EPR spectra are asymmetric, with characteristics for Cu 2+ (3d9) ions in axially-distorted octahedral symmetric sites. Due to the interaction of the unpaired electron spin (s = 1/2) with the nuclear one (I = 3/2) of Cu 2+ ions, the characteristic hyperfine structure (hfs) is visible for small concentrations of CuO in both spectra bands (parallel and perpendicular). The increasing of copper content in the samples generates the EPR absorption spectra modification, the hfs being resolved in the parallel band of the spectra in whole compositional range, while in the perpendicular band, hfs disappear for x > 3 mol %. This fact indicates the structural modification in Cu 2+ vicinity and possible magnetic interactions.

scholarly journals Intracellular Hypoxia of Tumor Tissue Estimated by Noninvasive Electron Paramagnetic Resonance Oximetry Technique Using Paramagnetic Probes

2011 ◽  
Vol 34 (1) ◽  
pp. 142-145 ◽  
Author(s):  
Atsuko Matsumoto ◽  
Ken-ichiro Matsumoto ◽  
Shingo Matsumoto ◽  
Fuminori Hyodo ◽  
Anastasia L. Sowers ◽  
...  
Keyword(s):  
Electron Paramagnetic Resonance ◽  
Tumor Tissue ◽  
Paramagnetic Resonance ◽  
Paramagnetic Probes ◽  
Electron Paramagnetic

scholarly journals Cellular labeling with Gd(III) chelates: only high thermodynamic stabilities prevent the cells acting as ‘sponges’ of Gd3+ ions

2006 ◽  
Vol 1 (1) ◽  
pp. 23-29 ◽  
Author(s):  
C. Cabella ◽  
S. Geninatti Crich ◽  
D. Corpillo ◽  
A. Barge ◽  
C. Ghirelli ◽  
...  
Keyword(s):  
Cellular Labeling

INTERACTIONS BETWEEN PVC AND SIMULATOR MEDIA USING PARAMAGNETIC PROBES

1995 ◽  
Vol 15 (1-2) ◽  
Author(s):  
A.M. Riquet ◽  
M. Hamdani ◽  
A. Feigenbaum
Keyword(s):  
Paramagnetic Probes

A new chemical procedure for the preparation of gangliosides carrying fluorescent or paramagnetic probes on the lipid moiety

1986 ◽  
Vol 40 (1) ◽  
pp. 71-86 ◽  
Author(s):  
Domenico Acquotti ◽  
Sandro Sonnino ◽  
Massimo Masserini ◽  
Luigi Casella ◽  
Giovanni Fronza ◽  
...  
Keyword(s):  
Lipid Moiety ◽  
Paramagnetic Probes ◽  
Chemical Procedure
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