ChemInform Abstract: Palladium-Catalyzed Site-Selective Arylation of Symmetric Dichlorobenzaldehyde to Non-symmetric Diaryl Benzaldehyde via Suzuki Coupling.

ChemInform ◽  
2012 ◽  
Vol 43 (29) ◽  
pp. no-no
Author(s):  
Raju Dey ◽  
Brindaban C. Ranu
Keyword(s):  
Suzuki Coupling ◽  
Palladium Catalyzed ◽  
Site Selective

Theoretical and experimental studies of palladium-catalyzed site-selective C(sp3)−H bond functionalization enabled by transient ligands

2017 ◽  
Author(s):  
Haibo Ge ◽  
Lei Pan ◽  
Piaoping Tang ◽  
Ke Yang ◽  
Mian Wang ◽  
...  
Keyword(s):  
Bond Activation ◽  
Theoretical Calculations ◽  
Experimental Studies ◽  
Bond Functionalization ◽  
Aliphatic Ketones ◽  
Site Selectivity ◽  
Mechanistic Investigation ◽  
Palladium Catalyzed ◽  
Metal Catalyzed ◽  
Site Selective

Transition metal-catalyzed selective C–H bond functionalization enabled by transient ligands has become an extremely attractive topic due to its economical and greener characteristics. However, catalytic pathways of this reaction process on unactivated sp<sup>3</sup> carbons of reactants have not been well studied yet. Herein, detailed mechanistic investigation on Pd-catalyzed C(sp<sup>3</sup>)–H bond activation with amino acids as transient ligands has been systematically conducted. The theoretical calculations showed that higher angle distortion of C(sp2)-H bond over C(sp3)-H bond and stronger nucleophilicity of benzylic anion over its aromatic counterpart, leading to higher reactivity of corresponding C(sp<sup>3</sup>)–H bonds; the angle strain of the directing rings of key intermediates determines the site-selectivity of aliphatic ketone substrates; replacement of glycine with β-alanine as the transient ligand can decrease the angle tension of the directing rings. Synthetic experiments have confirmed that β-alanine is indeed a more efficient transient ligand for arylation of β-secondary carbons of linear aliphatic ketones than its glycine counterpart.<br><br>

scholarly journals Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,6-Enynes: Reaction Scope and Mechanism.

ChemInform ◽  
2005 ◽  
Vol 36 (31) ◽  
Author(s):  
Gangguo Zhu ◽  
Xiaofeng Tong ◽  
Jiang Cheng ◽  
Yanhui Sun ◽  
Dao Li ◽  
...  
Keyword(s):  
Suzuki Coupling ◽  
Palladium Catalyzed ◽  
Tandem Cyclization

ChemInform Abstract: One-Pot Synthesis of Arylketones from Aromatic Acids via Palladium-Catalyzed Suzuki Coupling.

ChemInform ◽  
2016 ◽  
Vol 47 (32) ◽  
Author(s):  
Hongxiang Wu ◽  
Baiping Xu ◽  
Yue Li ◽  
Fengying Hong ◽  
Dezhao Zhu ◽  
...  
Keyword(s):  
Suzuki Coupling ◽  
Aromatic Acids ◽  
One Pot ◽  
One Pot Synthesis ◽  
Palladium Catalyzed

scholarly journals Palladium-catalyzed borylation and Suzuki coupling (BSC) to obtain β-substituted dehydroamino acid derivatives

2003 ◽  
Vol 44 (32) ◽  
pp. 6007-6009 ◽  
Author(s):  
Ana S. Abreu ◽  
Natália O. Silva ◽  
Paula M.T. Ferreira ◽  
Maria-João R.P. Queiroz
Keyword(s):  
Suzuki Coupling ◽  
Palladium Catalyzed ◽  
Dehydroamino Acid

ChemInform Abstract: Efficient Synthesis of Racemic and Chiral Alkenyl Sulfoxides by Palladium-Catalyzed Suzuki Coupling.

ChemInform ◽  
2010 ◽  
Vol 41 (48) ◽  
pp. no-no
Author(s):  
Gisela Mancha ◽  
Ana B. Cuenca ◽  
Nuria Rodriguez ◽  
Mercedes Medio-Simon ◽  
Gregorio Asensio
Keyword(s):  
Suzuki Coupling ◽  
Efficient Synthesis ◽  
Palladium Catalyzed

ChemInform Abstract: Generation of Diverse 2-Pyrones via Palladium-Catalyzed Site-Selective Suzuki-Miyaura Couplings of 3-Bromo-4-tosyloxy-2-pyrone.

ChemInform ◽  
2012 ◽  
Vol 43 (8) ◽  
pp. no-no
Author(s):  
Xiaoli Lei ◽  
Liang Gao ◽  
Qiuping Ding ◽  
Yiyuan Peng ◽  
Jie Wu
Keyword(s):  
Palladium Catalyzed ◽  
Site Selective
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