ChemInform Abstract: One-Pot Synthesis of Pyrazoline Derivatized Carbazoles as Antitubercular, Anticancer Agents, Their DNA Cleavage and Antioxidant Activities.

ChemInform ◽  
2012 ◽  
Vol 43 (5) ◽  
pp. no-no
Author(s):  
Tasneem Taj ◽  
Ravindra R. Kamble ◽  
T. M. Gireesh ◽  
Raveendra K. Hunnur ◽  
Sheetal B. Margankop
Keyword(s):  
Anticancer Agents ◽  
Dna Cleavage ◽  
Antioxidant Activities ◽  
One Pot ◽  
One Pot Synthesis

One-pot synthesis of pyrazoline derivatised carbazoles as antitubercular, anticancer agents, their DNA cleavage and antioxidant activities

2011 ◽  
Vol 46 (9) ◽  
pp. 4366-4373 ◽  
Author(s):  
Tasneem Taj ◽  
Ravindra R. Kamble ◽  
T.M. Gireesh ◽  
Raveendra K. Hunnur ◽  
Sheetal B. Margankop
Keyword(s):  
Anticancer Agents ◽  
Dna Cleavage ◽  
Antioxidant Activities ◽  
One Pot ◽  
One Pot Synthesis

One Pot Synthesis of N-monoalkylated Plinabulin Derivatives via Multicomponent Protocol and their application as Anticancer Agents

2020 ◽  
pp. 129830
Author(s):  
Asha Ganesher ◽  
Priyank Chaturvedi ◽  
Bidhu Bhusan Karkara ◽  
Indranil Chatterjee ◽  
Dipak Datta ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
One Pot ◽  
One Pot Synthesis

ChemInform Abstract: An Efficient One-Pot Synthesis of Heterocycle-Fused 1,2,3-Triazole Derivatives as Anticancer Agents.

ChemInform ◽  
2010 ◽  
Vol 42 (3) ◽  
pp. no-no
Author(s):  
Sheng-Jiao Yan ◽  
Yong-Jiang Liu ◽  
Yu-Lan Chen ◽  
Lin Liu ◽  
Jun Lin
Keyword(s):  
Anticancer Agents ◽  
One Pot ◽  
Triazole Derivatives ◽  
One Pot Synthesis

One-pot synthesis of new fluorinated 4H-1,4-benzothiazines as possible anticancer agents

1989 ◽  
Vol 44 (1) ◽  
pp. 1-14 ◽  
Author(s):  
R.R. Gupta ◽  
A. Thomas ◽  
R.K. Gautam ◽  
V. Gupta
Keyword(s):  
Anticancer Agents ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals EFFICIENT ONE POT SYNTHESIS, In-vitro ANTIOXIDANT ACTIVITIES OF Zn(II) COMPLEX WITH (E)-N1[(E)-3- PHENYLALLYLIDENE]BENZENE-1,2-DIAMINE

2021 ◽  
Vol 14 (02) ◽  
pp. 861-870
Author(s):  
R. Selvarani ◽  
S. Balasubramaniyan ◽  
K. Rajasekar ◽  
C. Veeravel ◽  
R. Geetha
Keyword(s):  
Antioxidant Activities ◽  
One Pot ◽  
One Pot Synthesis

One-pot synthesis of some new regioseletive 4β-pyrazolepodophyllotoxins as DNA topoisomerase-II targeting anticancer agents

2021 ◽  
pp. 131724
Author(s):  
Rajkumar Nagavath ◽  
Satheesh Kumar Nukala ◽  
Narsimha Sirassu ◽  
Ravikumar Reddy Sagam ◽  
Ravinder Manchal ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Topoisomerase Ii ◽  
Dna Topoisomerase Ii ◽  
One Pot ◽  
Dna Topoisomerase ◽  
One Pot Synthesis

An efficient, one-pot synthesis of N-isatinylmethylthioacetic acid and its derivatives as potential anticancer agents

2014 ◽  
Vol 55 (47) ◽  
pp. 6495-6499 ◽  
Author(s):  
Lev Yu. Ukhin ◽  
Arina R. Akopova ◽  
Anatolii S. Morkovnik ◽  
Kirill Yu. Suponitzky ◽  
Evgenii N. Shepelenko ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
One Pot ◽  
One Pot Synthesis

Phenanthridine derivatives as promising new anticancer agents: synthesis, biological evaluation and binding studies

2020 ◽  
Vol 12 (8) ◽  
pp. 709-739 ◽  
Author(s):  
Iqbal Azad ◽  
Rumana Ahmad ◽  
Tahmeena Khan ◽  
Mohammad Saquib ◽  
Firoj Hassan ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Dna Cleavage ◽  
High Resolution Mass Spectrometry ◽  
Biological Evaluation ◽  
Binding Studies ◽  
Binding Properties ◽  
One Pot ◽  
Docking Analysis ◽  
Dna Cleavage Activity

Aim: Phenanthridines are an essential class of nitrogenous heterocycles with extensive applications in medicinal chemistry. The development of efficient and eco-friendly methods for the preparation of chirally pure dihydropyrrolo[1,2- f]phenanthridines (5a–h), and their in vitro evaluation and modeling studies as potential anticancer, antioxidant and DNA cleavage agents is reported. Methodology & results: Compounds 5a–h were prepared through a facile one-pot synthesis and characterized by infrared, high resolution mass spectrometry, 1H and 13C nuclear magnetic resonance. The molecules were subjected to virtual screening and docking analysis against selected human molecular targets. Compound 5g displayed good binding properties as well as significant anticancer and DNA cleavage activity. Conclusion: Compound 5g has been identified as a potential lead candidate for further testing against additional cancer cell lines and animal models in future.

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