ChemInform Abstract: Tetraazacyclotetradecane Species as Models of the Polyazacrown Macrocycles: Molecular Structure and Reorganizations in Aqueous Media (pH 0-14) as Probed by NMR Spectroscopy and Computational Methods - Problems and Solutions

ChemInform ◽  
2011 ◽  
Vol 42 (36) ◽  
pp. no-no
Author(s):  
Ryszard B. Nazarski
Keyword(s):  
Molecular Structure ◽  
Nmr Spectroscopy ◽  
Computational Methods ◽  
Aqueous Media ◽  
Problems And Solutions

Structure elucidation by NMR spectroscopy: Assisted analysis from spectra to molecular structure

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
S Groscurth ◽  
T Kühn ◽  
P Kessler ◽  
V Rukachaisirikul
Keyword(s):  
Molecular Structure ◽  
Nmr Spectroscopy ◽  
Structure Elucidation ◽  
Assisted Analysis

Determination of Relative Configuration in Organic Compounds by NMR Spectroscopy and Computational Methods

ChemInform ◽  
2007 ◽  
Vol 38 (50) ◽  
Author(s):  
Giuseppe Bifulco ◽  
Paolo Dambruoso ◽  
Luigi Gomez-Paloma ◽  
Raffaele Riccio
Keyword(s):  
Nmr Spectroscopy ◽  
Organic Compounds ◽  
Computational Methods ◽  
Relative Configuration

Conformational study of a strained tolanophane by dynamic 1H NMR spectroscopy and computational methods

2008 ◽  
Vol 139 (10) ◽  
pp. 1185-1189 ◽  
Author(s):  
Hossein Reza Darabi ◽  
Marjan Azimzadeh Arani ◽  
Mohsen Tafazzoli ◽  
Mina Ghiasi
Keyword(s):  
Nmr Spectroscopy ◽  
1H Nmr ◽  
Computational Methods ◽  
1H Nmr Spectroscopy ◽  
Conformational Study ◽  
Dynamic 1H Nmr

scholarly journals Detection and Investigation of Some Properties of the Regulators of Antibiotic Biosynthesis Produced by Streptomyces Strains S. sp. AN26 and S. sp. B35

2021 ◽  
Vol 83 (6) ◽  
pp. 49-54
Author(s):  
B.P. Matselyukh ◽  
Keyword(s):  
Molecular Structure ◽  
Nmr Spectroscopy ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Transcriptional Regulators ◽  
Signaling Molecules ◽  
Molecular Structures ◽  
Antibiotic Biosynthesis ◽  
Future Studies ◽  
Layer Chromatography

The aim of this work was the isolation, purification and some properties investigation of two regulators of antibiotic biosynthesis of streptomycetes. Methods includes extraction of regulators from agar cultures and their concentration by vacuum rotary evaporator, thin layer chromatography and spectrophotometry. Results. Two strains of streptomycetes AN26 and B35 isolated from soils of different regions of Ukraine produce the regulators restoring the landomycin E biosynthesis and sporulation in mutant strain Streptomyces globispoprus 1912-B2. Both regulators were purified by thin layer chromatography and have the same Rf 0.69. Absorption curves of regulators were established by means of spectrophotometry. Maxima of absorption of regulators were 232.5 nm. The next study of the isolated regulators by means of NMR will give the possibility to elucidate their molecular structures. Conclusions. It is shown that two strains of streptomycetes isolated from the soils of Askania Nova and Brovary produce transcriptional regulators such as signaling molecules, which, like A-factor, restore the biosynthesis of antibiotics landomycin E and streptomycin in test strains S. globisporus 1912-B2 and S. griseis 1439, respectively. In terms of absorption maxima, they are similar and differ from similar indicators of known regulators of streptomycetes. It is possible that these compounds belong to new, not yet described signaling molecules, and the answer to this question will give future studies of their molecular structure by NMR spectroscopy.

3. Making sense of genes and genomes

2018 ◽  
pp. 28-43
Author(s):  
John Archibald
Keyword(s):  
Dna Sequencing ◽  
Computational Methods ◽  
Genome Assembly ◽  
Physical Nature ◽  
Living Cells ◽  
Shotgun Sequencing ◽  
Significant Challenge ◽  
Making Sense ◽  
Problems And Solutions ◽  
Balancing Efficiency

While DNA sequencing is faster and cheaper than ever before, genome assembly remains a significant challenge. ‘Making sense of genes and genomes’ explores how laboratory and computational methods are used in combination to elucidate the true physical nature of DNA molecules inside living cells, and how genes are identified among the vast quantities of chemical letters making up an organism’s genome. It begins with shotgun sequencing—a method that has stood the test of time in balancing efficiency and accuracy. It then considers the problems and solutions of genome assembly; gene finding with transcriptomics; the BLAST algorithm; how to find where proteins carry out their functions; and genome re-sequencing.

The molecular structure of 3(5)-methyl-4,5(3)-trimethylenepyrazole hydrochloride and its13C and15N NMR spectroscopy

1993 ◽  
Vol 23 (12) ◽  
pp. 961-965 ◽  
Author(s):  
Monique Perrin ◽  
Alain Thozet ◽  
Sylvain Lecocq ◽  
Jose Elguero ◽  
Ana Martinez ◽  
...  
Keyword(s):  
Molecular Structure ◽  
Nmr Spectroscopy
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