ChemInform Abstract: Inexpensive and Efficient Synthesis of Propargylic Substituted Active Methylene Compounds Catalyzed by FeCl3.

ChemInform ◽  
2011 ◽  
Vol 42 (29) ◽  
pp. no-no
Author(s):  
Sukhendu Maiti ◽  
Srijit Biswas ◽  
Umasish Jana
2005 ◽  
Vol 70 (15) ◽  
pp. 5890-5895 ◽  
Author(s):  
Ji Zhang ◽  
Koushik Das Sarma ◽  
Timothy T. Curran ◽  
Daniel T. Belmont ◽  
James G. Davidson

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Suresh Kumar

AbstractA simple, efficient and solvent free approach for the Knoevenagel condensation has been developed which involves grinding of active methylene compounds with aromatic aldehydes over basic alumina. Using this solvent free Knoevenagel approach, a facile and efficient synthesis of 3-cyano and 3-carbethoxycoumarins has also been developed, which involves the grinding of 2-hydroxybenzaldehydes with malononitrile or ethylcyanoacetate respectively over basic alumina followed by grinding with p-toluenesulphonic acid (PTSA) in the same mortar.


The reaction between substituted 4-hydroxybenzaldehyde, active methylene compounds and /or resorcinol yield aminochromene derivatives. Structures of these compounds were established upon the basis of IR,1HNMR,13CNMR,and MASSdata


Synlett ◽  
2019 ◽  
Vol 30 (13) ◽  
pp. 1565-1572
Author(s):  
Mengyao Li ◽  
Yinghong Zhu ◽  
Haibin Wang ◽  
Wanli Chen

The Et3N-promoted tandem cyclization of bromomaleimides with active methylene compounds is presented, providing an efficient method for the synthesis of cis-3,4-dihydropyrrolidine-2,5-diones in moderate to good yields under mild conditions.


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