ChemInform Abstract: A Novel Aminothiazole Derivative Induces Apoptosis and Cell Cycle Arrest in Tumor Cells.

ChemInform ◽  
2011 ◽  
Vol 42 (12) ◽  
pp. no-no
Author(s):  
Minghua Li ◽  
Changwon Oh ◽  
Jun Seok Park ◽  
Seung Wook Ham
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Cycle Arrest

INI1 expression induces cell cycle arrest and markers of senescence in malignant rhabdoid tumor cells

2003 ◽  
Vol 194 (3) ◽  
pp. 303-313 ◽  
Author(s):  
Britta S. Reincke ◽  
Gary B. Rosson ◽  
Betty W. Oswald ◽  
Cynthia F. Wright
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Rhabdoid Tumor ◽  
Malignant Rhabdoid Tumor ◽  
Cycle Arrest

scholarly journals Tristetraprolin induces cell cycle arrest in breast tumor cells through targeting AP-1/c-Jun and NF-κB pathway

Oncotarget ◽  
2015 ◽  
Vol 6 (39) ◽  
pp. 41679-41691 ◽  
Author(s):  
Li Xu ◽  
Huan Ning ◽  
Ling Gu ◽  
Qinghong Wang ◽  
Wenbao Lu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Breast Tumor ◽  
Breast Tumor Cells ◽  
Cycle Arrest

scholarly journals Novel Tools to Analyze the Function of Salmonella Effectors Show That SvpB Ectopic Expression Induces Cell Cycle Arrest in Tumor Cells

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e78458 ◽  
Author(s):  
Beatriz Mesa-Pereira ◽  
Carlos Medina ◽  
Eva María Camacho ◽  
Amando Flores ◽  
Eduardo Santero
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Ectopic Expression ◽  
Cycle Arrest

scholarly journals The Methanol Extract ofAngelica sinensisInduces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Yu-Ling Lin ◽  
Wen-Lin Lai ◽  
Horng-jyh Harn ◽  
Pei-Hsiu Hung ◽  
Ming-Chang Hsieh ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Brain Tumor ◽  
Brain Tumors ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Methanol Extract ◽  
Cycle Arrest ◽  
Anticancer Effects ◽  
Brain Tumor Cells

Glioblastoma multiforme (GBM) is a highly vascularized and invasive neoplasm. The methanol extract ofAngelica sinensis(AS-M) is commonly used in traditional Chinese medicine to treat several diseases, such as gastric mucosal damage, hepatic injury, menopausal symptoms, and chronic glomerulonephritis. AS-M also displays potency in suppressing the growth of malignant brain tumor cells. The growth suppression of malignant brain tumor cells by AS-M results from cell cycle arrest and apoptosis. AS-M upregulates expression of cyclin kinase inhibitors, including p16, to decrease the phosphorylation of Rb proteins, resulting in arrest at the G0-G1phase. The expression of the p53 protein is increased by AS-M and correlates with activation of apoptosis-associated proteins. Therefore, the apoptosis of cancer cells induced by AS-M may be triggered through the p53 pathway. Inin vivostudies, AS-M not only suppresses the growth of human malignant brain tumors but also significantly prolongs patient survival. In addition, AS-M has potent anticancer effects involving cell cycle arrest, apoptosis, and antiangiogenesis. Thein vitroandin vivoanticancer effects of AS-M indicate that this extract warrants further investigation and potential development as a new antibrain tumor agent, providing new hope for the chemotherapy of malignant brain cancer.

NSAIDs inhibit growth of human neuroendocrine tumor cells via G1 cell cycle arrest

2003 ◽  
Vol 124 (4) ◽  
pp. A458-A459
Author(s):  
Katharina M. Detjen ◽  
Martina Welzel ◽  
Bertram Wiedenmann ◽  
Stefan Rosewicz
Keyword(s):  
Cell Cycle ◽  
Neuroendocrine Tumor ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Cycle Arrest ◽  
G1 Cell Cycle Arrest

β-Ionone Induces Cell Cycle Arrest and Apoptosis in Human Prostate Tumor Cells

2013 ◽  
Vol 65 (4) ◽  
pp. 600-610 ◽  
Author(s):  
Sheila Jones ◽  
Nicolle V. Fernandes ◽  
Hoda Yeganehjoo ◽  
Rajasekhar Katuru ◽  
Haibin Qu ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Prostate Tumor ◽  
Human Prostate ◽  
Cycle Arrest ◽  
Prostate Tumor Cells ◽  
Human Prostate Tumor

scholarly journals Induction of efficient apoptosis and cell-cycle arrest in tumor cells by adenovirus-mediated p53 A4 mutant

2006 ◽  
Vol 56 (3) ◽  
pp. 126-134 ◽  
Author(s):  
Akihiro Maeda ◽  
Seiichi Nakamura ◽  
Masato Isono ◽  
Mitsuhiko Osaki ◽  
Hisao Ito ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Cycle Arrest

scholarly journals A Novel Aminothiazole Derivative Induces Apoptosis and Cell Cycle Arrest in Tumor Cells

2010 ◽  
Vol 31 (11) ◽  
pp. 3454-3456 ◽  
Author(s):  
Minghua Li ◽  
Chang-Won Oh ◽  
Jun-Seok Park ◽  
Seung-Wook Ham
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Tumor Cells ◽  
Cycle Arrest
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