ChemInform Abstract: Discovery of MK-0952 (I), a Selective PDE4 Inhibitor for the Treatment of Long-Term Memory Loss and Mild Cognitive Impairment.

ChemInform ◽  
2011 ◽  
Vol 42 (8) ◽  
pp. no-no
Author(s):  
Michel Gallant ◽  
et al. et al.
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Memory Loss ◽  
Pde4 Inhibitor ◽  
Long Term Memory ◽  
Term Memory

Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment

2010 ◽  
Vol 20 (22) ◽  
pp. 6387-6393 ◽  
Author(s):  
Michel Gallant ◽  
Renee Aspiotis ◽  
Stephen Day ◽  
Rebecca Dias ◽  
Daniel Dubé ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Memory Loss ◽  
Pde4 Inhibitor ◽  
Long Term Memory ◽  
Term Memory

P1-464: Episodic long-term memory as a predictor of change from retrieval to storage memory profile in amnestic mild cognitive impairment

2011 ◽  
Vol 7 ◽  
pp. S262-S262
Author(s):  
Emma Rodriguez-Noriega ◽  
Mikel Olabarrieta ◽  
Francesc Pujadas ◽  
Marta Ibarria ◽  
Diana Liebana ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Amnestic Mild Cognitive Impairment ◽  
Long Term Memory ◽  
Term Memory

scholarly journals Gender aspects of mild cognitive impairment

2009 ◽  
Vol 8 (3(2)) ◽  
pp. 36-38
Author(s):  
N. I. Skulskaya ◽  
M. V. Nadezhdina ◽  
Ye. V. Osinceva ◽  
M. N. Zhezher
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Tests ◽  
Long Term Memory ◽  
Men And Women ◽  
Term Memory ◽  
Gender Aspects

Neuropsychological research and analysis of level testosterone and estradiol among men and women at age from 50 to 60 were carried out. Two groups were formed. The first group was of patients with complaints bad memory and concentration, and the second group was of patients with out any complaints. The change for certain of results the neuropsychological tests between two groups of patients were fixed. The results of long-term memory were more sensible. The correlation between different level of testosterone and results of neuropsychological tests among men and women was fixed. The correlation between level of estradiol and results of neuropsychological tests was not fixed.

P2-309: Long-Term Memory Functioning in Age-Associated Memory Impairment and Mild Cognitive Impairment

2016 ◽  
Vol 12 ◽  
pp. P755-P755
Author(s):  
Rebecca Crean ◽  
Gary Kay ◽  
Donald Connor ◽  
Jamie Reiter ◽  
Joseph Djan ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Memory Impairment ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Functioning

Altered neural network supporting declarative long-term memory in mild cognitive impairment

2009 ◽  
Vol 30 (2) ◽  
pp. 284-298 ◽  
Author(s):  
Katrin Poettrich ◽  
Peter H. Weiss ◽  
Annett Werner ◽  
Silke Lux ◽  
Markus Donix ◽  
...  
Keyword(s):  
Neural Network ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Long Term Memory ◽  
Term Memory

Benefits of training working memory in amnestic mild cognitive impairment: specific and transfer effects

2012 ◽  
Vol 25 (4) ◽  
pp. 617-626 ◽  
Author(s):  
Barbara Carretti ◽  
Erika Borella ◽  
Silvia Fostinelli ◽  
Michela Zavagnin
Keyword(s):  
Working Memory ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Fluid Intelligence ◽  
Amnestic Mild Cognitive Impairment ◽  
Control Group ◽  
Long Term Memory ◽  
Transfer Effects ◽  
Memory Problems

ABSTRACTBackground:A growing number of studies are attempting to understand how effective cognitive interventions may be for patients with amnestic mild cognitive impairment (aMCI), particularly in relation to their memory problems.Methods:The present study aimed to explore the benefits of a working memory (WM) training program in aMCI patients. Patients (N= 20) were randomly assigned to two training programs: the experimental group practiced with a verbal WM task, while the active control group conducted educational activities on memory.Results:Results showed that the aMCI patients completing the WM training obtained specific gains in the task trained with some transfer effects on other WM measures (visuospatial WM) and on processes involved in or related to WM, e.g. fluid intelligence (the Cattell test) and long-term memory. This was not the case for the aMCI control group, who experienced only a very limited improvement.Conclusion:This pilot study suggests that WM training could be a valuable method for improving cognitive performance in aMCI patients, possibly delaying the onset of Alzheimer's disease.

Facing a Long-Term Memory Loss

2011 ◽  
Vol 39 (2) ◽  
pp. 53-54
Author(s):  
Kevin Mccarty
Keyword(s):  
Memory Loss ◽  
Long Term Memory ◽  
Term Memory
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