ChemInform Abstract: Structure and Antibacterial Activity of Brominated Diterpenes from the Red Alga Sphaerococcus coronopifolius.

ChemInform ◽  
2010 ◽  
Vol 41 (23) ◽  
pp. no-no
Author(s):  
Vangelis Smyrniotopoulos ◽  
Constantinos Vagias ◽  
Mukhlesur M. Rahman ◽  
Simon Gibbons ◽  
Vassilios Roussis
2013 ◽  
Vol 8 (3) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Takashi Kamada ◽  
Charles Santhanaraju Vairappan

A Bornean red algal population of Laurencia simlis Nam et Saito was analyzed for its secondary metabolite composition. Seven compounds were identified: ent -1(10)-aristolen-9β-ol (1), (+)-aristolone (2), axinysone B (3), 9-aristolen-1α-ol (4), 2,3,5,6-tetrabromoindole (5), 1-methyl-2,3,5,6-tetrabromoindole (6), and 1-methyl-2,3,5-tribromoindole (7). Compound 1 was identified as a new optical isomer of 1(10)-aristolen-9β-ol. Compounds 1, 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical bacteria and cytotoxic effects against selected cancer cell lines.


Author(s):  
Subbiah Murugesan ◽  
Sundaresan Bhuvaneswari ◽  
U.S. Mahadeva Rao ◽  
Vajiravelu Sivamurugan

2020 ◽  
Author(s):  
Joe Bracegirdle ◽  
Z Sohail ◽  
Michael Fairhurst ◽  
Monica Gerth ◽  
Giuseppe Zuccarello ◽  
...  

© 2019 by the authors Red algae of the genus Plocamium have been a rich source of halogenated monoterpenes. Herein, a new cyclic monoterpene, costatone C (7), was isolated from the extract of P. angustum collected in New Zealand, along with the previously reported (1E,5Z)-1,6-dichloro-2-methylhepta-1,5-dien-3-ol (8). Elucidation of the planar structure of 7 was achieved through conventional NMR and (−)-HR-APCI-MS techniques, and the absolute configuration by comparison of experimental and DFT-calculated ECD spectra. The absolute configuration of 8 was determined using Mosher’s method. Compound 7 showed mild antibacterial activity against Staphylococcus aureus and S. epidermidis. The state of Plocamium taxonomy and its implications upon natural product distributions, especially across samples from specimens collected in different countries, is also discussed.


2007 ◽  
Vol 2 (7) ◽  
pp. 1934578X0700200
Author(s):  
Samira Etahiri ◽  
Abdel Kebir El Kouria ◽  
Valérie Bultel-Poncé ◽  
Michèle Guyot ◽  
Omar Assobhei

The dichloromethane/methanol extract of the red alga Pterosiphonia complanata exhibited antibacterial activity against many potentially pathogenic Gram (+) and Gram (-) bacteria. The compound responsible for this activity was isolated and identified, mainly on the basis of 1H and 13C NMR experiments, as the known 3,4,6-tribromo-5-methoxymethyl-benzene-1,2-diol. Its minimum inhibitory concentration against Staphylococcus aureus was 2.8 μg/mL (7 nM).


Marine Drugs ◽  
2019 ◽  
Vol 17 (7) ◽  
pp. 418 ◽  
Author(s):  
Joe Bracegirdle ◽  
Zaineb Sohail ◽  
Michael J. Fairhurst ◽  
Monica L. Gerth ◽  
Giuseppe C. Zuccarello ◽  
...  

Red algae of the genus Plocamium have been a rich source of halogenated monoterpenes. Herein, a new cyclic monoterpene, costatone C (7), was isolated from the extract of P. angustum collected in New Zealand, along with the previously reported (1E,5Z)-1,6-dichloro-2-methylhepta-1,5-dien-3-ol (8). Elucidation of the planar structure of 7 was achieved through conventional NMR and (−)-HR-APCI-MS techniques, and the absolute configuration by comparison of experimental and DFT-calculated ECD spectra. The absolute configuration of 8 was determined using Mosher’s method. Compound 7 showed mild antibacterial activity against Staphylococcus aureus and S. epidermidis. The state of Plocamium taxonomy and its implications upon natural product distributions, especially across samples from specimens collected in different countries, is also discussed.


2019 ◽  
Vol 31 (5) ◽  
pp. 3201-3212 ◽  
Author(s):  
Elmi Nurhaidah Zainuddin ◽  
Hilal Anshary ◽  
Huyyirnah Huyyirnah ◽  
Ridha Hiola ◽  
Dolores V. Baxa

ChemInform ◽  
2010 ◽  
Vol 33 (41) ◽  
pp. no-no
Author(s):  
Mark T. D. Cronin ◽  
et al. et al.

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