ChemInform Abstract: Synthetic Approach to Polysubstituted Furans: An Efficient Addition/Oxidative Cyclization of Alkynoates and 1,3-Dicarbonyl Compounds.

ChemInform ◽  
2010 ◽  
Vol 41 (22) ◽  
pp. no-no
Author(s):  
Weibing Liu ◽  
Huanfeng Jiang ◽  
Min Zhang ◽  
Chaorong Qi
Keyword(s):  
Oxidative Cyclization ◽  
Synthetic Approach ◽  
Dicarbonyl Compounds

ChemInform Abstract: Oxidative Cyclization of Dialdehydes with Alcohols and 1,3-Dicarbonyl Compounds under Rh(III)/Cu(II) Conditions.

ChemInform ◽  
2016 ◽  
Vol 47 (12) ◽  
pp. no-no
Author(s):  
Takanori Matsuda ◽  
Kentaro Suzuki ◽  
Shinya Abe ◽  
Haruki Kirikae ◽  
Noboru Okada
Keyword(s):  
Oxidative Cyclization ◽  
Dicarbonyl Compounds

A Highly Efficient Heterogeneous Copper-Catalyzed Oxidative Cyclization of Benzylamines and 1,3-Dicarbonyl Compounds To Give Trisubstituted Oxazoles

Synthesis ◽  
2019 ◽  
Vol 51 (16) ◽  
pp. 3091-3100
Author(s):  
Li Wei ◽  
Shengyong You ◽  
Yuxin Tuo ◽  
Mingzhong Cai
Keyword(s):  
Copper Catalyst ◽  
Oxidative Cyclization ◽  
Dicarbonyl Compounds ◽  
Mild Conditions ◽  
Highly Efficient ◽  
Intermolecular Cyclization ◽  
Step Procedure ◽  
Mcm 41

The heterogeneous copper-catalyzed cascade oxidative cyclization between benzylamines and 1,3-dicarbonyl compounds was achieved by using the 3-(2-aminoethylamino)propyl-functionalized MCM-41-immobilized copper(II) complex [MCM-41-2N-Cu(OAc)2] as catalyst and t-BuOOH (TBHP) as oxidant, with iodine as additive, under mild conditions, yielding a wide variety of 2,4,5-trisubstituted oxazoles in mostly good to excellent yields. This heterogeneous copper catalyst can be facilely prepared via a simple two-step procedure from readily available and inexpensive reagents and exhibits a slightly higher activity than Cu(OAc)2. MCM-41-2N-Cu(OAc)2 is also easy to recover and can be recycled up to eight times with almost consistent activity. The reaction is the first example of heterogeneous copper-catalyzed intermolecular cyclization for the construction of polysubstituted oxazoles.

Hypoiodite-catalysed oxidative cyclisation of Michael adducts of chalcones with 1,3-dicarbonyl compounds: a facile and versatile approach to substituted furans and cyclopropanes

2016 ◽  
Vol 52 (89) ◽  
pp. 13097-13100 ◽  
Author(s):  
Wen-Chao Gao ◽  
Fei Hu ◽  
Jun Tian ◽  
Xing Li ◽  
Wen-Long Wei ◽  
...  
Keyword(s):  
Oxidative Cyclization ◽  
Dicarbonyl Compounds ◽  
Michael Adducts ◽  
Oxidative Cyclisation ◽  
Substituted Furans

Hypoiodite catalysis for selective oxidative cyclization has been developed, yielding either furans or cyclopropanes with excellent diastereoselectivity.

Asymmetric total synthesis of (+)-ovafolinins A and B

2018 ◽  
Vol 54 (54) ◽  
pp. 7539-7541
Author(s):  
Xianhe Fang ◽  
Lei Shen ◽  
Xiangdong Hu
Keyword(s):  
Total Synthesis ◽  
Oxidative Cyclization ◽  
Synthetic Approach ◽  
Asymmetric Total Synthesis

Benefiting from a highly diastereoselective alkylation of (S)-Taniguchi lactone, a double Friedel–Crafts reaction, a global debenzylation and a Cu(OAc)2-enabled benzylic oxidative cyclization, an efficient synthetic approach to (+)-ovafolinins A and B has been developed.

Michael reaction of methylenemalonaldehydes: Synthetic approach to 4H-pyran-5-carboxaldehydes and 2-amino-4H-pyran-5-carboxaldehydes

1987 ◽  
Vol 52 (11) ◽  
pp. 2687-2698 ◽  
Author(s):  
Dalimil Dvořák ◽  
David Šaman ◽  
Jana Hodačová ◽  
Vladimír Král ◽  
Zdeněk Arnold
Keyword(s):  
Acid Medium ◽  
Michael Reaction ◽  
Nitrile Group ◽  
Synthetic Approach ◽  
Dicarbonyl Compounds

Base-catalyzed addition of β-dicarbonyl compounds to methylenemalonaldehydes led to tetracarbonyl compounds II which were dehydrated in an acid medium to 4H-pyran-5-carboxaldehydes III. In the addition of compounds containing a nitrile group, the primarily formed addition products were immediately cyclized to give directly 2-amino-4H-pyran-5-carboxaldehydes V.

Oxidative cyclization of dialdehydes with alcohols and 1,3-dicarbonyl compounds under Rh(III)/Cu(II) conditions

Tetrahedron ◽  
2015 ◽  
Vol 71 (49) ◽  
pp. 9264-9270 ◽  
Author(s):  
Takanori Matsuda ◽  
Kentaro Suzuki ◽  
Shinya Abe ◽  
Haruki Kirikae ◽  
Noboru Okada
Keyword(s):  
Oxidative Cyclization ◽  
Dicarbonyl Compounds
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