ChemInform Abstract: One-Pot Derivatization of Medicinally Important 9-Aminoacridines by Reductive Amination and SNAr Reaction.

ChemInform ◽  
2010 ◽  
Vol 41 (18) ◽  
Author(s):  
Gary Gellerman ◽  
Vladimir Gaisin ◽  
Tamara Brider
Keyword(s):  
Reductive Amination ◽  
One Pot ◽  
Snar Reaction

One-pot derivatization of medicinally important 9-aminoacridines by reductive amination and SNAr reaction

2010 ◽  
Vol 51 (5) ◽  
pp. 836-839 ◽  
Author(s):  
Gary Gellerman ◽  
Vladimir Gaisin ◽  
Tamara Brider
Keyword(s):  
Reductive Amination ◽  
One Pot ◽  
Snar Reaction

Cobalt encapsulated in N‑doped graphene sheet for one-pot reductive amination to synthesize secondary amines

2021 ◽  
Vol 505 ◽  
pp. 111504
Author(s):  
Lin Liu ◽  
Wenxiu Li ◽  
Ran Qi ◽  
Qingqing Zhu ◽  
Jing Li ◽  
...  
Keyword(s):  
Graphene Sheet ◽  
Reductive Amination ◽  
Secondary Amines ◽  
One Pot ◽  
Doped Graphene

scholarly journals Facile Synthesis of COF-Supported Reduced Pd-Based Catalyst for One-Pot Reductive Amination of Aldehydes

Catalysts ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 287
Author(s):  
Jianguo Liu ◽  
Mingyue Zhang ◽  
Longlong Ma
Keyword(s):  
Heterogeneous Catalysts ◽  
Reductive Amination ◽  
Secondary Amines ◽  
Metallic State ◽  
One Pot ◽  
Effective Synthesis ◽  
Pharmaceutical Industries ◽  
The One ◽  
Heterocyclic Aldehydes ◽  
Supported Pd

Dibenzylamine motifs are an important class of crucial organic compounds and are widely used in fine chemical and pharmaceutical industries. The development of the efficient, economical, and environmentally friendly synthesis of amines using transition metal-based heterogeneous catalysts remains both desirable and challenging. Herein, we prepared the covalent organic framework (COF)-supported heterogeneous reduced COF-supported Pd-based catalyst and used it for the one-pot reductive amination of aldehydes. There are both Pd metallic state and oxidated Pdσ+ in the catalysts. Furthermore, in the presence of the reduced COF-supported Pd-based catalyst, many aromatic, aliphatic, and heterocyclic aldehydes with various functional groups substituted were converted to their corresponding amines products in good to excellent selectivity (up to 91%) under mild reaction conditions (70 °C, 2 h, NH3, 20 bar H2). This work expands the covalent organic frameworks for the material family and its support catalyst, opening up new catalytic applications in the economical, practical, and effective synthesis of secondary amines.

One-pot reductive amination of aldehydes and ketones with α-picoline-borane in methanol, in water, and in neat conditions

Tetrahedron ◽  
2004 ◽  
Vol 60 (36) ◽  
pp. 7899-7906 ◽  
Author(s):  
Shinya Sato ◽  
Takeshi Sakamoto ◽  
Etsuko Miyazawa ◽  
Yasuo Kikugawa
Keyword(s):  
Reductive Amination ◽  
One Pot ◽  
Aldehydes And Ketones

Direct reductive amination of aldehydes using lithium-arene(cat.) as reducing system. A simple one-pot procedure for the synthesis of secondary amines

2012 ◽  
Vol 53 (25) ◽  
pp. 3156-3160 ◽  
Author(s):  
Fabiana Nador ◽  
Yanina Moglie ◽  
Andrés Ciolino ◽  
Adriana Pierini ◽  
Viviana Dorn ◽  
...  
Keyword(s):  
Reductive Amination ◽  
Secondary Amines ◽  
One Pot ◽  
System A

One-Pot Reductive Amination of Carbonyl Compounds Using Sodium Borohydride–Amberlyst 15

2010 ◽  
Vol 40 (7) ◽  
pp. 951-956 ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Mahmood Tajbakhsh ◽  
Nastaran Mahdavi
Keyword(s):  
Sodium Borohydride ◽  
Carbonyl Compounds ◽  
Reductive Amination ◽  
One Pot ◽  
Amberlyst 15

scholarly journals An efficient catalytic reductive amination: A facile one-pot access to 1,2-dihydropyrrolo[3,4-b]indol-3(4H)-ones by using B(C 6 F 5 ) 3 /NaBH 4

2015 ◽  
Vol 127 (4) ◽  
pp. 711-716 ◽  
Author(s):  
ATULYA NAGARSENKAR ◽  
SANTOSH KUMAR PRAJAPTI ◽  
BATHINI NAGENDRA BABU
Keyword(s):  
Reductive Amination ◽  
One Pot

(±)-1,2-Dialkyl-5-nitro-2,3-dihydro-1H-indoles by a tandem reductive amination-SNAr reaction

2009 ◽  
Vol 46 (4) ◽  
pp. 629-634 ◽  
Author(s):  
Richard A. Bunce ◽  
Takahiro Nago ◽  
Brian White
Keyword(s):  
Reductive Amination ◽  
Snar Reaction
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