ChemInform Abstract: Synthesis of Amino Acid Derivatives via Asymmetric Hydrogenation

ChemInform ◽  
2010 ◽  
Vol 41 (5) ◽  
Author(s):  
Hideo Shimizu ◽  
Izuru Nagasaki ◽  
Noboru Sayo ◽  
Takao Saito
Keyword(s):  
Amino Acid ◽  
Asymmetric Hydrogenation ◽  
Amino Acid Derivatives

Synthesis of chiral α-substituted α-amino acid and amine derivatives through Ni-catalyzed asymmetric hydrogenation

2020 ◽  
Vol 56 (36) ◽  
pp. 4934-4937 ◽  
Author(s):  
Gongyi Liu ◽  
Xianghe Zhang ◽  
Heng Wang ◽  
Hengjiang Cong ◽  
Xumu Zhang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Asymmetric Hydrogenation ◽  
Amino Acid Derivatives

Efficient Ni-catalyzed asymmetric hydrogenation of cyclic N-sulfonyl ketimino esters and ketimines was successfully developed to prepare a series of chiral α-monosubstituted α-amino acid derivatives and amine derivatives with excellent results.

Enantioselective synthesis of β-amino acid derivatives via nickel-promoted regioselective carboxylation of ynamides and rhodium-catalyzed asymmetric hydrogenation

2016 ◽  
Vol 14 (42) ◽  
pp. 10080-10089 ◽  
Author(s):  
Nozomi Saito ◽  
Iman Abdullah ◽  
Kayoko Hayashi ◽  
Katsuyuki Hamada ◽  
Momoko Koyama ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Active Form ◽  
Asymmetric Hydrogenation ◽  
Optically Active ◽  
Enantioselective Synthesis ◽  
Amino Acid Derivatives

Nickel-promoted carboxylation of ynamides followed by rhodium-catalyzed asymmetric hydrogenation provided α-substituted-β-amino acids in an optically active form.

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