ChemInform Abstract: Efficient Synthesis of Heterocyclic Compounds Using Ethenetricarboxylic Acid Diesters.

ChemInform ◽  
2009 ◽  
Vol 40 (28) ◽  
Author(s):  
Shoko Yamazaki ◽  
Yuko Iwata ◽  
Yugo Fukushima
Tetrahedron ◽  
2001 ◽  
Vol 57 (39) ◽  
pp. 8349-8356 ◽  
Author(s):  
Vijay Nair ◽  
Bini Mathew ◽  
Nigam P Rath ◽  
M Vairamani ◽  
S Prabhakar

2021 ◽  
Vol 25 ◽  
Author(s):  
Wei Liang ◽  
Li-Jing Min ◽  
Liang Han ◽  
Xing-Hai Liu

: 1,4-benzoxazine compounds are an important class of heterocyclic compounds. Ever since 1,4-benzoxazine was discovered in 1959, it has attracted chemists due to its unique physiological activities, and their synthesis and application have been studied. However, the traditional synthesis methods of 1,4-benzoxazines have some drawbacks, such as complicated steps, harsh reaction conditions and low yield. Therefore, it is still a significant direction to develop new and efficient synthesis methods. In this paper, the synthesis methods and reaction mechanisms of these compounds are reviewed, and the application prospect of 1,4- benzoxazine and its derivatives as a dominant active structure in the future is discussed.


RSC Advances ◽  
2016 ◽  
Vol 6 (81) ◽  
pp. 77931-77936 ◽  
Author(s):  
Chunhao Yuan ◽  
Leijie Zhou ◽  
Zhanhu Sun ◽  
Hongchao Guo

The phosphine-catalyzed [3 + 2] cycloaddition has been achieved at room temperature, providing novel heterocyclic compounds, 1,2,3,10b-tetrahydropyrrolo[2,1-a]phthalazine derivatives, as single (Z)-isomers in excellent yields (88–99% yield).


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