ChemInform Abstract: Biologically Active Secondary Metabolites from Fungi. Part 39. Dinemasones A (I), B (II) and C (III) - New Bioactive Metabolites from the Endophytic Fungus Dinemasporium strigosum.

ChemInform ◽  
2009 ◽  
Vol 40 (12) ◽  
Author(s):  
Karsten Krohn ◽  
Md. Hossain Sohrab ◽  
Teunis van Ree ◽  
Siegfried Draeger ◽  
Barbara Schulz ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Endophytic Fungus ◽  
Biologically Active ◽  
Bioactive Metabolites

ChemInform Abstract: Biologically Active Secondary Metabolites from Fungi. Part 51. Phomopsinones A-D: Four New Pyrenocines from Endophytic Fungus Phomopsis sp.

ChemInform ◽  
2012 ◽  
Vol 43 (31) ◽  
pp. no-no
Author(s):  
Hidayat Hussain ◽  
Karsten Krohn ◽  
Ishtiaq Ahmed ◽  
Siegfried Draeger ◽  
Barbara Schulz ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Endophytic Fungus ◽  
Biologically Active

scholarly journals PCR-screening of bacterial strains isolated from the microbiome of the Lubomirskia baicalensis sponge for the presence of secondary metabolite synthesis genes

2021 ◽  
pp. 1137-1142
Author(s):  
O.V. Kaluzhnaya ◽  
◽  
I.A. Lipko ◽  
V.B. Itskovich ◽  
◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Taxonomic Diversity ◽  
Biologically Active ◽  
Rapid Screening ◽  
Bioactive Metabolites ◽  
Bacterial Strains ◽  
Degenerate Primers ◽  
Pcr Screening ◽  
Lubomirskia Baicalensis ◽  
Taxonomic Groups

Abstract. The microbial communities of sponges (Porifera) are often a source of natural bioactive metabolites. From the microbiome of the endemic Lubomirskia baicalensis sponge, 35 bacterial strains were isolated and identified using molecular methods. The strains belonged to the phyla Actinobacteria, Firmicutes, and Proteobacteria (classes Alpha- and Betapriteobacteria). To analyze the strains for the presence of genes in the synthesis of secondary metabolites, polyketide synthases (PKS), PCR screening was applied using degenerate primers. Overall, 15 out of 35 strains contained PCR products corresponding in size to a fragment of the ketosynthase domain of the PKS gene cluster. Thus, the proposed method is applicable for rapid screening of the potential ability of microorganisms of different taxonomic groups to produce secondary metabolites. The work contributes to the study of the taxonomic diversity of cultured microorganisms, potential producers of biologically active substances, isolated from the microbiomes of Baikal sponges.

scholarly journals Bioactive metabolites of Cunninghamella, Biodiversity to Biotechnology

2021 ◽  
Vol 4 (3) ◽  
pp. 01-05
Author(s):  
Waill A. Elkhateeb ◽  
Abdu Ghalib AL Kolaibe ◽  
Ghoson M. Daba
Keyword(s):  
Secondary Metabolites ◽  
Endophytic Fungus ◽  
Antimicrobial Agents ◽  
Biological Activities ◽  
Industrial Applications ◽  
Bioactive Metabolites ◽  
Promising Tool ◽  
Fungal Genus

Cunninghamella is a fungal genus that belongs to family Cunninghamellaceae and has been involved as promising tool in many important mycotechnological applications. Cunninghamella is an endophytic fungus, their secondary metabolites are of potential biological activities especially as antimicrobial agents. The aim of this review is to highlight the description, ecology, and important in medicinal and industrial applications of the genus Cunninghamella in general. Moreover, describing the importance and potentials of this fungus in order to encourage for further studies to search, isolate, and purify already known metabolites. Also, screen for, and discover novel metabolites produced by this potent fungi in order to be involved in additional applications.

Metabolomics of Healthy Berry Fruits

2019 ◽  
Vol 25 (37) ◽  
pp. 4888-4902 ◽  
Author(s):  
Gilda D'Urso ◽  
Sonia Piacente ◽  
Cosimo Pizza ◽  
Paola Montoro
Keyword(s):  
Biological Activities ◽  
Biologically Active ◽  
In Vivo Studies ◽  
Bioactive Metabolites ◽  
Active Metabolites ◽  
Positive Effects ◽  
Cell Functions ◽  
Berry Fruits

The consumption of berry-type fruits has become very popular in recent years because of their positive effects on human health. Berries are in fact widely known for their health-promoting benefits, including prevention of chronic disease, cardiovascular disease and cancer. Berries are a rich source of bioactive metabolites, such as vitamins, minerals, and phenolic compounds, mainly anthocyanins. Numerous in vitro and in vivo studies recognized the health effects of berries and their function as bioactive modulators of various cell functions associated with oxidative stress. Plants have one of the largest metabolome databases, with over 1200 papers on plant metabolomics published only in the last decade. Mass spectrometry (MS) and NMR (Nuclear Magnetic Resonance) are the most important analytical technologies on which the emerging ''omics'' approaches are based. They may provide detection and quantization of thousands of biologically active metabolites from a tissue, working in a ''global'' or ''targeted'' manner, down to ultra-trace levels. In the present review, we highlighted the use of MS and NMR-based strategies and Multivariate Data Analysis for the valorization of berries known for their biological activities, important as food and often used in the preparation of nutraceutical formulations.

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