ChemInform Abstract: Chemoenzymatic Synthesis of Deoxy Analogues of the DNA Topoisomerase II Inhibitor Eleutherin and the 3C-Protease Inhibitor Thysanone.

Prabhakar Bachu; Jonathan Sperry; Margaret A. Brimble

doi:10.1002/chin.200839205

ChemInform Abstract: Chemoenzymatic Synthesis of Deoxy Analogues of the DNA Topoisomerase II Inhibitor Eleutherin and the 3C-Protease Inhibitor Thysanone.

ChemInform ◽

10.1002/chin.200839205 ◽

2008 ◽

Vol 39 (39) ◽

Author(s):

Prabhakar Bachu ◽

Jonathan Sperry ◽

Margaret A. Brimble

Keyword(s):

Protease Inhibitor ◽

Topoisomerase Ii ◽

Chemoenzymatic Synthesis ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor ◽

3C Protease

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Chemoenzymatic synthesis of deoxy analogues of the DNA topoisomerase II inhibitor eleutherin and the 3C-protease inhibitor thysanone

Tetrahedron ◽

10.1016/j.tet.2008.01.112 ◽

2008 ◽

Vol 64 (21) ◽

pp. 4827-4834 ◽

Cited By ~ 20

Author(s):

Prabhakar Bachu ◽

Jonathan Sperry ◽

Margaret A. Brimble

Keyword(s):

Protease Inhibitor ◽

Topoisomerase Ii ◽

Chemoenzymatic Synthesis ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor ◽

3C Protease

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4-Methyl-7-(tetradecanoyl)-2H-1-benzopyran-2-one: a novel DNA topoisomerase II inhibitor with adulticidal and embryostatic activity against sub-periodic Brugia malayi

Parasitology Research ◽

10.1007/s00436-003-1014-3 ◽

2004 ◽

Vol 92 (3) ◽

pp. 177-182 ◽

Cited By ~ 20

Author(s):

Shailja Misra-Bhattacharya ◽

Diksha Katiyar ◽

Preeti Bajpai ◽

R.P. Tripathi ◽

J.K. Saxena

Keyword(s):

Topoisomerase Ii ◽

Brugia Malayi ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor

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HY-2, a novel DNA topoisomerase II inhibitor, induces G2/M cell cycle arrest in HCT-116 cells

Journal of Chemotherapy ◽

10.1179/1973947813y.0000000153 ◽

2013 ◽

Vol 26 (6) ◽

pp. 342-347 ◽

Cited By ~ 2

Author(s):

Zhonghua Wu ◽

Yu Zhao ◽

Yuting Zhang ◽

Li Zhu

Keyword(s):

Cell Cycle ◽

Cell Cycle Arrest ◽

Topoisomerase Ii ◽

Dna Topoisomerase Ii ◽

M Cell ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor ◽

Cycle Arrest ◽

Hct 116 ◽

Hct 116 Cells

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Cellular Resistance to the Antitumor DNA Topoisomerase II Inhibitor S16020-2: Importance of the N-[2(Dimethylamino)ethyl]carbamoyl Side Chain

Molecular Pharmacology ◽

10.1124/mol.58.4.709 ◽

2000 ◽

Vol 58 (4) ◽

pp. 709-718 ◽

Cited By ~ 5

Author(s):

Sandrine Le Mée ◽

Françoise Chaminade ◽

Charlotte Delaporte ◽

Judith Markovits ◽

Jean-Marie Saucier ◽

...

Keyword(s):

Topoisomerase Ii ◽

Side Chain ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Cellular Resistance ◽

Topoisomerase Ii Inhibitor

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ChemInform Abstract: Podophyllotoxin Aza-Analogue, a Novel DNA Topoisomerase II Inhibitor.

ChemInform ◽

10.1002/chin.200038248 ◽

2000 ◽

Vol 31 (38) ◽

pp. no-no

Author(s):

Akira Iida ◽

Masahiro Kano ◽

Yoshihiro Kubota ◽

Kenji Koga ◽

Kiyoshi Tomioka

Keyword(s):

Topoisomerase Ii ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor

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Chromosomal malsegregation and micronucleus induction in vitro by the DNA topoisomerase II inhibitor fisetin

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2005.01.002 ◽

2005 ◽

Vol 582 (1-2) ◽

pp. 79-86 ◽

Cited By ~ 29

Author(s):

A.J. Olaharski ◽

S.T. Mondrala ◽

D.A. Eastmond

Keyword(s):

Topoisomerase Ii ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor ◽

Micronucleus Induction

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Effects of the DNA topoisomerase II inhibitor merbarone in male mouse meiotic divisions in vivo: Cell cycle arrest and induction of aneuploidy

Environmental and Molecular Mutagenesis ◽

10.1002/(sici)1098-2280(1997)29:1<16::aid-em3>3.0.co;2-b ◽

1997 ◽

Vol 29 (1) ◽

pp. 16-27 ◽

Cited By ~ 34

Author(s):

Morko Kallio ◽

Jaana Lähdetie

Keyword(s):

Cell Cycle ◽

Cell Cycle Arrest ◽

Male Mouse ◽

Topoisomerase Ii ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor ◽

Cycle Arrest

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Increased cytotoxicity of an unusual DNA topoisomerase II inhibitor compound C-1305 toward HeLa cells with downregulated PARP-1 activity results from re-activation of the p53 pathway and modulation of mitotic checkpoints

Biochemical Pharmacology ◽

10.1016/j.bcp.2009.12.023 ◽

2010 ◽

Vol 79 (10) ◽

pp. 1387-1397 ◽

Cited By ~ 14

Author(s):

Michal Sabisz ◽

Józefa Węsierska-Gądek ◽

Andrzej Skladanowski

Keyword(s):

Hela Cells ◽

Topoisomerase Ii ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

P53 Pathway ◽

Topoisomerase Ii Inhibitor ◽

Mitotic Checkpoints ◽

Compound C ◽

Parp 1

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Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action

British Journal of Pharmacology ◽

10.1038/sj.bjp.0705795 ◽

2004 ◽

Vol 142 (3) ◽

pp. 485-494 ◽

Cited By ~ 21

Author(s):

Dierk Thomas ◽

Bettina C Hammerling ◽

Kezhong Wu ◽

Anna-Britt Wimmer ◽

Eckhard K Ficker ◽

...

Keyword(s):

Mode Of Action ◽

Topoisomerase Ii ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor

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The Catalytic DNA Topoisomerase II Inhibitor Dexrazoxane (ICRF-187) Induces Differentiation and Apoptosis in Human Leukemia K562 Cells

Molecular Pharmacology ◽

10.1124/mol.59.3.453 ◽

2001 ◽

Vol 59 (3) ◽

pp. 453-461 ◽

Cited By ~ 41

Author(s):

Brian B. Hasinoff ◽

Michael E. Abram ◽

Norman Barnabé ◽

Tayeb Khélifa ◽

William P. Allan ◽

...

Keyword(s):

Topoisomerase Ii ◽

K562 Cells ◽

Human Leukemia ◽

Dna Topoisomerase Ii ◽

Dna Topoisomerase ◽

Topoisomerase Ii Inhibitor ◽

Catalytic Dna ◽

Human Leukemia K562 Cells

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