ChemInform Abstract: Asymmetric Iodocyclization Catalyzed by Salen-CrIIICl: Its Synthetic Application to Swainsonine.

ChemInform ◽  
2008 ◽  
Vol 39 (22) ◽  
Author(s):  
Hyo Young Kwon ◽  
Chul Min Park ◽  
Sung Bae Lee ◽  
Joo-Hack Youn ◽  
Sung Ho Kang
Keyword(s):  
Synthetic Application

Synthesis of allylic alcohol single-chain PGH analogs. A synthetic application of the argon laser

1986 ◽  
Vol 51 (21) ◽  
pp. 4028-4035 ◽  
Author(s):  
R. Marshall Wilson ◽  
Karlyn A. Schnapp ◽  
Richard K. Merwin ◽  
Revathi Ranganthan ◽  
David L. Moats ◽  
...  
Keyword(s):  
Argon Laser ◽  
Allylic Alcohol ◽  
Single Chain ◽  
Synthetic Application

scholarly journals 2-Aryl-6-Polyfluoroalkyl-4-Pyrones as Promising RF-Building-Blocks: Synthesis and Application for Construction of Fluorinated Azaheterocycles

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4415
Author(s):  
Sergey A. Usachev ◽  
Diana I. Nigamatova ◽  
Daria K. Mysik ◽  
Nikita A. Naumov ◽  
Dmitrii L. Obydennov ◽  
...  
Keyword(s):  
Direct Synthesis ◽  
Building Blocks ◽  
Oxidative Cyclization ◽  
One Pot ◽  
Synthetic Application ◽  
General Method

A convenient and general method for the direct synthesis of 2-aryl-6-(trifluoromethyl)-4-pyrones and 2-aryl-5-bromo-6-(trifluoromethyl)-4-pyrones has been developed on the basis of one-pot oxidative cyclization of (E)-6-aryl-1,1,1-trifluorohex-5-ene-2,4-diones via a bromination/dehydrobromination approach. This strategy was also applied for the preparation of 2-phenyl-6-polyfluoroalkyl-4-pyrones and their 5-bromo derivatives. Conditions of chemoselective enediones bromination were found and the key intermediates of the cyclization of bromo-derivatives to 4-pyrones were characterized. Synthetic application of the prepared 4-pyrones has been demonstrated for the construction of biologically important CF3-bearing azaheterocycles, such as pyrazoles, pyridones, and triazoles.

Base-Free Synthesis and Synthetic Application of Novel 3-(organochalcogenyl)prop-2-yn-1-yl Esters: Promising Anticancer Agents

Synthesis ◽  
2021 ◽  
Author(s):  
Fabiane Gritzenco ◽  
Jean Carlo Kazmierczak ◽  
Thiago Anjos ◽  
Adriane Sperança ◽  
Maura Luise Bruckchem Peixoto ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Chalcogen Bond ◽  
Cross Coupling Reactions ◽  
Air Atmosphere ◽  
Carbon Carbon Bonds ◽  
Palladium Catalyzed ◽  
Synthetic Application

This manuscript portrays the CuI-catalyzed Csp-chalcogen bond formation through cross-coupling reactions of propynyl esters and diorganyl dichalcogenides by using DMSO as solvent, at room temperature, under base-free and open-to-air atmosphere. Generally, the reactions have proceeded very smoothly, being tolerant to range of substituents present in both substrates, affording the novel 3-(organochalcogenyl)prop-2-yn-1-yl esters in moderate to good yields. Noteworthy, the 3-(butylselanyl)prop-2-yn-1-yl benzoate proved to be useful as synthetic precursor in palladium-catalyzed Suzuki and Sonogashira type cross-coupling reactions by replacing the carbon-chalcogen bond by new carbon-carbon bonds. Moreover, the 3-(phenylselanyl)prop-2-yn-1-yl benzoate has shown promising in vitro activity against glioblastoma cancer cells.

ChemInform Abstract: Regioselective Hydroalumination of Allenes and Their Synthetic Application.

ChemInform ◽  
2010 ◽  
Vol 25 (13) ◽  
pp. no-no
Author(s):  
S. NAGAHARA ◽  
K. MARUOKA ◽  
H. YAMAMOTO
Keyword(s):  
Synthetic Application

Crystal Structure of 1-(2,4,6-Trichlorobenzoyloxy) Benzotriazole (TCB-OBt): Observation of uncommon intermolecular oxygen-oxygen interaction and synthetic application in amidation

2021 ◽  
Author(s):  
Gobinda Dolai ◽  
Sayanta Roy ◽  
Srijit Sen ◽  
Rajat Subhra Giri ◽  
Bhubaneswar Mandal
Keyword(s):  
Crystal Structure ◽  
Supramolecular Assembly ◽  
Hirshfeld Surface ◽  
Oxygen Oxygen ◽  
Synthetic Application ◽  
Oxygen Interaction

Herein, we investigated the supramolecular assembly of a Modified Yamaguchi Reagent TCB-OBt. Interestingly, each molecule is interconnected through novel chalcogen-chalcogen (O…O) interaction, - stacking, and aromatic C-H…O interaction. Hirshfeld surface...

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