Three-Component Green Synthesis of N-Arylquinoline Derivatives in Ionic Liquid [Bmim+][BF4-]: Reactions of Arylaldehyde, 3-Arylamino-5,5-dimethylcyclohex-2-enone, and Active Methylene Compounds.

ChemInform ◽  
2007 ◽  
Vol 38 (35) ◽  
Author(s):  
Xiang-Shan Wang ◽  
Mei-Mei Zhang ◽  
Hong Jiang ◽  
Chang-Sheng Yao ◽  
Shu-Jiang Tu
Keyword(s):  
Ionic Liquid ◽  
Green Synthesis ◽  
Active Methylene Compounds ◽  
Active Methylene

Ionic-liquid-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene — An efficient and recyclable organocatalyst for Michael addition to α,β-unsaturated ketones

2012 ◽  
Vol 90 (3) ◽  
pp. 290-297 ◽  
Author(s):  
Manoj Kumar Muthyala ◽  
Bhupender S Chhikara ◽  
Keykavous Parang ◽  
Anil Kumar
Keyword(s):  
Ionic Liquid ◽  
Michael Addition ◽  
Room Temperature ◽  
Significant Loss ◽  
Unsaturated Ketones ◽  
Ability To Act ◽  
Solvent Free Conditions ◽  
Active Methylene Compounds ◽  
Active Methylene ◽  
The Michael Addition

A novel ionic-liquid-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (IL–TBD) was synthesized and investigated for its ability to act as an active organocatalyst in the Michael addition of active methylene compounds and thiophenols to chalcones under solvent-free conditions. The IL–TBD afforded Michael addition products in excellent yields (82%–94%) at room temperature, and it was simply recycled and reused at least five times without significant loss of catalytic activity.

Potassium phosphate–ionic liquid mediated selective mono-Michael addition

2015 ◽  
Vol 39 (9) ◽  
pp. 6726-6729 ◽  
Author(s):  
Anand D. Sawant ◽  
Suryabala D. Jagadale ◽  
Uday V. Desai ◽  
Manikrao M. Salunkhe
Keyword(s):  
Ionic Liquid ◽  
Michael Addition ◽  
Room Temperature ◽  
Potassium Phosphate ◽  
Nmr Analysis ◽  
Active Methylene Compounds ◽  
Dosy Nmr ◽  
Active Methylene

A process for exclusive mono-Michael addition of active methylene compounds to conjugated esters, nitriles and ketones is developed. An ionic liquid-mediated reaction is carried out at room temperature. A reaction carried out at 60 °C resulted in a double-addition. A mechanism is proposed and supported by P31 and DOSY NMR analysis.

An Efficient and Green Microwave-Assisted Synthesis of Quinoline DerivativesviaKnoevengal Condensation

2020 ◽  
Vol 17 (2) ◽  
pp. 157-163 ◽  
Author(s):  
Syed Tasqeeruddin ◽  
Yahya Asiri ◽  
Jaber Abdullah Alsherhri
Keyword(s):  
Green Synthesis ◽  
Knoevenagel Condensation ◽  
Microwave Assisted Synthesis ◽  
Quinoline Derivatives ◽  
Efficient Catalyst ◽  
Microwave Assisted ◽  
Active Methylene Compounds ◽  
Active Methylene ◽  
Quinolone Derivatives

:We have developed an efficient and green synthesis of quinoline derivatives using L-proline under Knoevenagel condensation. L-proline was found to be an efficient catalyst for the Knoevenagel condensation of substituted 2-aminoaryl ketones 1 with the active methylene compounds 2, affording quinolone derivatives 3. The reaction has been done under conventional as well as under microwave conditions. The latter procedure has been found to be much more efficient in terms of time and yield.

ChemInform Abstract: Condensation Reactions of Aromatic Aldehydes with Active Methylene Compounds Catalyzed by Alkaline Ionic Liquid.

ChemInform ◽  
2012 ◽  
Vol 43 (10) ◽  
pp. no-no
Author(s):  
Dong-Yue Wang ◽  
Guo-Hong Xi ◽  
Jing-Jun Ma ◽  
Chun Wang ◽  
Xiao-Chao Zhang ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Aromatic Aldehydes ◽  
Condensation Reactions ◽  
Active Methylene Compounds ◽  
Active Methylene
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