An Orthogonal Protection Strategy for the Synthesis of 2-Substituted Piperazines.

ChemInform ◽  
2007 ◽  
Vol 38 (30) ◽  
Author(s):  
Roger B. Clark ◽  
Daniel Elbaum
Keyword(s):  
Protection Strategy ◽  
Orthogonal Protection

Synthesis of Nanotubule-Forming Cyclic Octapeptides via an Fmoc Strategy

1998 ◽  
Vol 51 (7) ◽  
pp. 535 ◽  
Author(s):  
Martina E. Polaskova ◽  
John N. Lambert ◽  
Nicholas J. Ede
Keyword(s):  
Aqueous Solutions ◽  
Infrared Absorption ◽  
Structural Studies ◽  
Protection Strategy ◽  
Fmoc Chemistry ◽  
Orthogonal Protection ◽  
Fmoc Strategy ◽  
Cyclic Octapeptide ◽  
Head To Tail Cyclization ◽  
Hydrogen Bonded

New syndiotactic cyclic octapeptides, namely cyclo(–D-Phe-L-Asp–D-Phe–L-Asn–D-Phe–L-Asp–D-Phe–L-Asn–) (1) and cyclo(–D-N-MeAla–L-Asp–D-N-MeAla–L-Asn–D-N-MeAla–L-Asp–D-N-MeAla–L-Asn–) (2), have been prepared, and preliminary structural studies have been conducted. The synthesis of the linear peptides was performed by using Fmoc chemistry, and head-to-tail cyclization was accomplished by using an orthogonal protection strategy and a support-bound cyclization step. Acidification of aqueous solutions of cyclic octapeptide (1) initiated formation of needlelike crystals whose morphology and infrared absorption behaviour suggested that they were hydrogen-bonded nanotubular aggregates of (1).

An orthogonal protection strategy for the synthesis of 2-substituted piperazines

Tetrahedron ◽  
2007 ◽  
Vol 63 (14) ◽  
pp. 3057-3065 ◽  
Author(s):  
Roger B. Clark ◽  
Daniel Elbaum
Keyword(s):  
Protection Strategy ◽  
Orthogonal Protection

Cloud Provider's Response to Multiple Models of Attack Behaviors

2019 ◽  
Vol 13 (4) ◽  
pp. 325-333
Author(s):  
Xu Liu ◽  
Xiaoqiang Di ◽  
Jinqing Li ◽  
Huamin Yang ◽  
Ligang Cong ◽  
...  
Keyword(s):  
Stackelberg Game ◽  
Multiple Models ◽  
Theoretic Model ◽  
Cloud Provider ◽  
Game Model ◽  
Attack Behavior ◽  
Behavior Model ◽  
Protection Strategy ◽  
Behavior Models ◽  
Optimal Protection

Background: User behavior models have been widely used to simulate attack behaviors in the security domain. We revised all patents related to response to attack behavior models. How to decide the protected target against multiple models of attack behaviors is studied. Methods: We utilize one perfect rational and three bounded rational behavior models to simulate attack behaviors in cloud computing, and then investigate cloud provider’s response based on Stackelberg game. The cloud provider plays the role of defender and it is assumed to be intelligent enough to predict the attack behavior model. Based on the prediction accuracy, two schemes are built in two situations. Results: If the defender can predict the attack behavior model accurately, a single-objective game model is built to find the optimal protection strategy; otherwise, a multi-objective game model is built to find the optimal protection strategy. Conclusion: The numerical results prove that the game theoretic model performs better in the corresponding situation.

scholarly journals Research on DC Protection Strategy in Multi-Terminal Hybrid HVDC System

Engineering ◽  
2021 ◽  
Author(s):  
Yuping Zheng ◽  
Jiawei He ◽  
Bin Li ◽  
Tonghua Wu ◽  
Wei Dai ◽  
...  
Keyword(s):  
Protection Strategy ◽  
Hvdc System
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