Synthesis of Oxepin- and Oxocin-Annulated Pyrimidine Derivatives by Claisen Rearrangement and Ring Closing Metathesis/Ring Closing Enyne Metathesis.

ChemInform ◽  
2007 ◽  
Vol 38 (22) ◽  
Author(s):  
Krishna C. Majumdar ◽  
Pradip K. Maji ◽  
Habibur Rahaman ◽  
Brindaban Roy
Keyword(s):  
Claisen Rearrangement ◽  
Enyne Metathesis ◽  
Pyrimidine Derivatives ◽  
Ring Closing Metathesis

scholarly journals Synthesis of fluorinated δ-lactams via cycloisomerization of gem-difluoropropargyl amides

2010 ◽  
Vol 6 ◽  
Author(s):  
Satoru Arimitsu ◽  
Gerald B Hammond
Keyword(s):  
Building Blocks ◽  
Alder Reaction ◽  
Diels Alder ◽  
Tandem Reaction ◽  
Enyne Metathesis ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis ◽  
Diels Alder Reaction

gem-Difluoro-1,7-enyne amides are suitable building blocks for the synthesis of difluorodihydropyridinones via a ring-closing metathesis reaction, and of 4,4-difluoro-3-oxoisoquinolines through a ring-closing metathesis–enyne metathesis tandem reaction. These products, in turn, undergo a Diels–Alder reaction to yield heterotricyclic systems in moderate to good yields.

Synthesis of a Simplified Analogue of Eleutherobin via a Claisen Rearrangement and Ring Closing Metathesis Strategy.

ChemInform ◽  
2005 ◽  
Vol 36 (35) ◽  
Author(s):  
Gary C. H. Chiang ◽  
Andrew D. Bond ◽  
Andrew Ayscough ◽  
Gilles Pain ◽  
Sylvie Ducki ◽  
...  
Keyword(s):  
Claisen Rearrangement ◽  
Ring Closing Metathesis

Synthesis of a simplified analogue of eleutherobin via a Claisen rearrangement and ring closing metathesis strategy

2005 ◽  
pp. 1860 ◽  
Author(s):  
Gary C. H. Chiang ◽  
Andrew D. Bond ◽  
Andrew Ayscough ◽  
Gilles Pain ◽  
Sylvie Ducki ◽  
...  
Keyword(s):  
Claisen Rearrangement ◽  
Ring Closing Metathesis

A Synthesis of Substituted 3,6-Dihydro-1H-benzo[c]oxocines via Claisen Rearrangement and Ring-closing Metathesis

Heterocycles ◽  
2002 ◽  
Vol 57 (11) ◽  
pp. 2021 ◽  
Author(s):  
Eng-Chi Wang ◽  
Chin-Cheng Wang ◽  
Ming-Kun Hsu ◽  
Keng-Shiang Huang
Keyword(s):  
Claisen Rearrangement ◽  
Ring Closing Metathesis

The Ruthenium-Catalyzed Domino Cross Enyne Metathesis/Ring-Closing Metathesis in the Synthesis of Enantioenriched Nitrogen-Containing Heterocycles

2020 ◽  
Vol 2020 (27) ◽  
pp. 4193-4207 ◽  
Author(s):  
Alberto Llobat ◽  
Jorge Escorihuela ◽  
Daniel M. Sedgwick ◽  
Miriam Rodenes ◽  
Raquel Román ◽  
...  
Keyword(s):  
Enyne Metathesis ◽  
Ring Closing Metathesis

scholarly journals Ring-closing-metathesis-based synthesis of annellated coumarins from 8-allylcoumarins

2018 ◽  
Vol 14 ◽  
pp. 2991-2998 ◽  
Author(s):  
Christiane Schultze ◽  
Bernd Schmidt
Keyword(s):  
Double Bond ◽  
Olefin Metathesis ◽  
Claisen Rearrangement ◽  
Allylic Oxidation ◽  
Allyl Ether ◽  
Ring Closing Metathesis ◽  
Wittig Olefination

8-Allylcoumarins are conveniently accessible through a microwave-promoted tandem Claisen rearrangement/Wittig olefination/cyclization sequence. They serve as a versatile platform for the annellation of five- to seven-membered rings using ring-closing olefin metathesis (RCM). Furano-, pyrano-, oxepino- and azepinocoumarins were synthesized from the same set of precursors using Ru-catalyzed double bond isomerizations and RCM in a defined order. One class of products, pyrano[2,3-f]chromene-2,8-diones, were inaccessible through direct RCM of an acrylate, but became available from the analogous allyl ether via an assisted tandem catalytic RCM/allylic oxidation sequence.

Ring-Closing Metathesis Approach to Cage Propellanes Containing Oxepane and Tetrahydrofuran Hybrid System

Synthesis ◽  
2017 ◽  
Vol 49 (24) ◽  
pp. 5339-5350 ◽  
Author(s):  
Sambasivarao Kotha ◽  
Subba Cheekatla ◽  
Darshan Mhatre
Keyword(s):  
Claisen Rearrangement ◽  
Alder Reaction ◽  
Diels Alder ◽  
Ring Closing Metathesis ◽  
Cage Compounds ◽  
Transannular Cyclization ◽  
Diels Alder Reaction ◽  
Grignard Addition ◽  
Key Steps ◽  
First Time

The preparation of a variety of structurally interesting oxygenated cage compounds involving atom-economic processes such as Claisen rearrangement, Diels–Alder reaction, [2+2] photocycloaddition, and ring-closing metathesis (RCM) as key steps is reported. For the first time, oxepane ring system is introduced in cage framework using olefin metathesis as a key step. These cage systems assembled here are difficult to prepare by traditional methods. The synthetic sequence described here opens up new routes to higher order polycycles containing heteroatoms without the involvement of protecting groups. Transannular cyclization observed during Grignard addition and the RCM protocol used here may be applicable to generate unknown oxygenated cage systems.

Sequential Aza-Claisen Rearrangement and Ring-Closing Metathesis as a Route to 1-Benzazepine Derivatives

Synlett ◽  
2008 ◽  
Vol 2008 (19) ◽  
pp. 3011-3015 ◽  
Author(s):  
Shital Chattopadhyay ◽  
Debalina Ghosh ◽  
Latibuddin Thander ◽  
Sanjay Ghosh
Keyword(s):  
Claisen Rearrangement ◽  
Ring Closing Metathesis
Sign in / Sign up

Export Citation Format

Share Document