Reaction of tert-Butyl Isocyanide and Dialkyl Acetylenedicarboxylates in the Presence of 2-Acetylbutyrolactone. Synthesis of Functionalized α-Methylene-γ-butyrolactones.

ChemInform ◽  
2006 ◽  
Vol 37 (40) ◽  
Author(s):  
Sakineh Asghari ◽  
Leila Mohammadi
Keyword(s):  
Tert Butyl ◽  
Dialkyl Acetylenedicarboxylates

scholarly journals A New and Efficient One-pot Synthesis of Trialkyl 6-tert-Butylamino-2H-pyran-2-one-3,4,5-tricarboxylates

1999 ◽  
Vol 23 (6) ◽  
pp. 368-369
Author(s):  
Issa Yavari ◽  
Abbas Ali Esmaili ◽  
Sakineh Asghari ◽  
Hamid Reza Bijanzadeh
Keyword(s):  
One Pot ◽  
Tert Butyl ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
High Yields

The highly reactive 1:1 intermediate produced in the reaction between tert-butyl isocyanide and dialkyl acetylenedicarboxylates is trapped by dialkyl 2-bromomalonates to yield the title compounds in fairly high yields.

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