FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738. Part 2. In vitro and in vivo Antifungal Activity.

ChemInform ◽  
2006 ◽  
Vol 37 (38) ◽  
Author(s):  
Ryuichi Kanasaki ◽  
Fumie Abe ◽  
Shigetada Furukawa ◽  
Koji Yoshikawa ◽  
Akihiko Fujie ◽  
...  
Author(s):  
Janet Herrada ◽  
Ahmed Gamal ◽  
Lisa Long ◽  
Sonia P. Sanchez ◽  
Thomas S. McCormick ◽  
...  

Antifungal activity of AmBisome against Candida auris was determined in vitro and in vivo. AmBisome showed MIC50 and MIC90 values of 1 and 2 μg/mL, respectively. Unlike conventional amphotericin B, significant in vivo efficacy was observed in the AmBisome 7.5 mg/kg -treated group in survival and reduction of kidney tissue fungal burden compared to the untreated group. Our data shows that AmBisome shows significant antifungal activity against C. auris in vitro as well as in vivo.


2020 ◽  
Vol 154 ◽  
pp. 112745
Author(s):  
Qiong Yang ◽  
Jiao Wang ◽  
Peng Zhang ◽  
Shengnan Xie ◽  
Xiaolong Yuan ◽  
...  

2015 ◽  
pp. 1563-1570 ◽  
Author(s):  
Idriss Talibi ◽  
Latifa Askarne ◽  
Hassan Boubaker ◽  
El Hassane Boudyach ◽  
Abdellah Ait Ben Oumar

2013 ◽  
Vol 33 ◽  
pp. 40-46 ◽  
Author(s):  
Claudia Fieira ◽  
Francieli Oliveira ◽  
Rubens Perez Calegari ◽  
Alessandra Machado ◽  
Alexandre Rodrigo Coelho

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S471-S472
Author(s):  
Emily Larkin ◽  
Lisa Long ◽  
Christopher Hager ◽  
Karen Joy Shaw ◽  
Mahmoud Ghannoum

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