Recent Progress of the Synthetic Studies of Biologically Active Marine Cyclic Peptides and Depsipeptides

ChemInform ◽  
2006 ◽  
Vol 37 (17) ◽  
Author(s):  
Yasumasa Hamada ◽  
Takayuki Shioiri
Keyword(s):  
Cyclic Peptides ◽  
Recent Progress ◽  
Biologically Active ◽  
Synthetic Studies

Recent Progress Towards Synthesis of the Indolizidine Alkaloid 195B

2020 ◽  
Vol 17 (2) ◽  
pp. 82-90 ◽  
Author(s):  
Ghodsi Mohammadi Ziarani ◽  
Fatemeh Mohajer ◽  
Zohreh kheilkordi
Keyword(s):  
Natural Products ◽  
Natural Product ◽  
Recent Progress ◽  
Human Life ◽  
Natural Compounds ◽  
Biologically Active ◽  
Pharmaceutical Chemistry ◽  
Biological Perspective ◽  
Highly Active

Background: Natural products have been received attention due to their importance in human life as those are biologically active. In this review, there are some reports through different methods related to the synthesis of the indolizidine 195B which was extracted from poisonous frog; however, due to respect nature, the synthesis of natural compounds such as indolizidine has been attracted much attention among scientists and researchers. Objective: This review discloses the procedures and methods to provide indolizidine 195B from 1989 to 2018 due to their importance as a natural product. Conclusion: There are several methods to give rise to the indolizidine 195B as a natural product that is highly active from the biological perspective in pharmaceutical chemistry. In summary, many protocols for the preparations of indolizidine 195B from various substrates, several reagents, and conditions have been reported from different aromatic and aliphatic.

Synthetic studies on biologically active natural products by a chemicoenzymatic approach

Tetrahedron ◽  
1984 ◽  
Vol 40 (1) ◽  
pp. 145-152 ◽  
Author(s):  
Masaji Ohno ◽  
Yukishige Ito ◽  
Masafumi Arita ◽  
Tomoyuki Shibata ◽  
Kunitomo Adachi ◽  
...  
Keyword(s):  
Natural Products ◽  
Biologically Active ◽  
Synthetic Studies ◽  
Active Natural

Synthetic studies of cyclotheonamides, cyclic peptides from marine sponges

1993 ◽  
pp. 72-75
Author(s):  
Jingen Deng ◽  
Yasumasa Hamada ◽  
Takayuki Shioiri
Keyword(s):  
Cyclic Peptides ◽  
Marine Sponges ◽  
Synthetic Studies

scholarly journals Modular synthesis of α-fluorinated arylmethanes via desulfonylative cross-coupling

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Masakazu Nambo ◽  
Jacky C.-H. Yim ◽  
Luiza B. O. Freitas ◽  
Yasuyo Tahara ◽  
Zachary T. Ariki ◽  
...  
Keyword(s):  
Biological Activity ◽  
Late Stage ◽  
Recent Progress ◽  
Cross Coupling ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Arylboronic Acids ◽  
Modular Synthesis ◽  
Synthetic Routes

Abstract α-Fluoromethylarenes are common substructures in pharmaceuticals and agrochemicals, with the introduction of fluorine often resulting in improved biological activity and stability. Despite recent progress, synthetic routes to α-fluorinated diarylmethanes are still rare. Herein we describe the Pd-catalyzed Suzuki-Miyaura cross-coupling of α-fluorinated benzylic triflones with arylboronic acids affording structurally diverse α-fluorinated diarylmethanes. The ease of synthesis of fluorinated triflones as the key starting materials enables powerful late-stage transformations of known biologically active compounds into fluorinated analogs.

Synthesis of biologically active cyclic peptides

Biopolymers ◽  
1981 ◽  
Vol 20 (9) ◽  
pp. 1785-1791 ◽  
Author(s):  
Nobuo Izumiya ◽  
Tetsuo Kato ◽  
Michinori Waki
Keyword(s):  
Cyclic Peptides ◽  
Biologically Active
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