Hydroxylated Analogues of the Orally Active Broad Spectrum Antifungal, Sch 51048 (1), and the Discovery of Posaconazole (Ib) [Sch 56592; 2 or (S,S)-5].

ChemInform ◽  
2006 ◽  
Vol 37 (14) ◽  
Author(s):  
Frank Bennett ◽  
et al. et al.
Keyword(s):  
Broad Spectrum ◽  
Orally Active

Highly stereoselective access to novel 2,2,4-substituted tetrahydrofurans by halocyclization: Practical chemoenzymatic synthesis of Sch 51048, a broad-spectrum orally active antifungal agent

1995 ◽  
Vol 36 (11) ◽  
pp. 1787-1790 ◽  
Author(s):  
Anil K Saksena ◽  
Viyyoor M Girijavallabhan ◽  
Raymond G Lovey ◽  
Russell E Pike ◽  
Haiyan Wang ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Antifungal Agent ◽  
Chemoenzymatic Synthesis ◽  
Orally Active

Enantioselective synthesis of the optical isomers of broad-spectrum orally active antifungal azoles, Sch 42538 and Sch 45012

1994 ◽  
Vol 4 (16) ◽  
pp. 2023-2028 ◽  
Author(s):  
Anil K. Saksena ◽  
Viyyoor M. Girijavallabhan ◽  
Raymond G. Lovey ◽  
Russell E. Pike ◽  
Jagdish A. Desai ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Enantioselective Synthesis ◽  
Optical Isomers ◽  
Orally Active

scholarly journals Laboratory studies with cefatrizine (SK&F 60771) a new broad-spectrum orally-active cephalosporin.

1975 ◽  
Vol 28 (8) ◽  
pp. 594-601 ◽  
Author(s):  
PAUL ACTOR ◽  
JOSEPH V. URI ◽  
LILLIAN PHILLIPS ◽  
CARL S. SACHS ◽  
JOSEPH R. GUARINI ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Laboratory Studies ◽  
Orally Active

Identification of an orally active carbazole aminoalcohol derivative with broad-spectrum anti-animal trypanosomiasis activity

Acta Tropica ◽  
2021 ◽  
pp. 105919
Author(s):  
Xiao-Li Cai ◽  
Weisi Wang ◽  
De-Hua Lai ◽  
Xuan Zhang ◽  
Junmin Yao ◽  
...  
Keyword(s):  
Broad Spectrum ◽  
Animal Trypanosomiasis ◽  
Orally Active
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