Dynamic Kinetic Resolution of α-Bromo Carboxylic Acid Derivatives in Asymmetric Nucleophilic Substitution with Chiral α-Amino Esters.

ChemInform ◽  
2005 ◽  
Vol 36 (47) ◽  
Author(s):  
Ji-yeon Chang ◽  
Eun-kyoung Shin ◽  
Hyun Jung Kim ◽  
Yongtae Kim ◽  
Yong Sun Park
Keyword(s):  
Carboxylic Acid ◽  
Nucleophilic Substitution ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
Amino Esters

Synthesis, characterization and antibacterial activities of N-tert-butoxycarbonyl-thiazolidine carboxylic acid

RSC Advances ◽  
2015 ◽  
Vol 5 (32) ◽  
pp. 24824-24833 ◽  
Author(s):  
Zhong-Cheng Song ◽  
Gao-Yuan Ma ◽  
Hai-Liang Zhu
Keyword(s):  
Hydrogen Bonding ◽  
Carboxylic Acid ◽  
Nucleophilic Substitution ◽  
Kinetic Resolution ◽  
Intramolecular Hydrogen Bonding ◽  
Antibacterial Activities ◽  
Dynamic Kinetic Resolution ◽  
Qualitative Explanation ◽  
Intramolecular Hydrogen

The mechanism of dynamic kinetic resolution, a nucleophilic substitution through an intramolecular hydrogen bonding by the formation of N-Boc-TCAs was proposed and a qualitative explanation was interpretated according to Curtin–Hammett principle.

Lipase-catalyzed kinetic and dynamic kinetic resolution of 1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid

2007 ◽  
Vol 18 (12) ◽  
pp. 1428-1433 ◽  
Author(s):  
Tihamér A. Paál ◽  
Enikő Forró ◽  
Arto Liljeblad ◽  
Liisa T. Kanerva ◽  
Ferenc Fülöp
Keyword(s):  
Carboxylic Acid ◽  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

A new cost-effective Ru-chloramphenicol base derivative catalyst for the asymmetric transfer hydrogenation/dynamic kinetic resolution of N-Boc α-amino-β-ketoesters and its application to the synthesis of the chiral core of vancomycin

RSC Advances ◽  
2016 ◽  
Vol 6 (44) ◽  
pp. 37701-37709 ◽  
Author(s):  
Xinlong Wang ◽  
Lingjun Xu ◽  
Fangjun Xiong ◽  
Yan Wu ◽  
Fener Chen
Keyword(s):  
Asymmetric Synthesis ◽  
Kinetic Resolution ◽  
Cost Effective ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Dynamic Kinetic Resolution ◽  
Amino Esters ◽  
Base Derivative

Herein we describe the application of Ru-chloramphenicol base complexes catalyzed highly diastereo- and enantioselective transfer hydrogenation of N-Boc α-amino-β-ketoesters for the asymmetric synthesis of anti-N-Boc-β-hydroxy-α-amino esters.

Asymmetric syntheses of N-substituted α-amino esters via dynamic kinetic resolution of α-haloacyl diacetone-d-glucose

Tetrahedron ◽  
2006 ◽  
Vol 62 (26) ◽  
pp. 6303-6311 ◽  
Author(s):  
Hyun Jung Kim ◽  
Yongtae Kim ◽  
Eui Ta Choi ◽  
Min Hee Lee ◽  
Eun Sun No ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
Asymmetric Syntheses ◽  
Amino Esters
Sign in / Sign up

Export Citation Format

Share Document