Enantioselective and Diastereoselective Synthesis of Fluorinated Dipeptides by Late Electrophilic Fluorination.

ChemInform ◽  
2005 ◽  
Vol 36 (44) ◽  
Author(s):  
Barbara Mohar ◽  
Damjan Sterk ◽  
Laurent Ferron ◽  
Dominique Cahard
Keyword(s):  
Diastereoselective Synthesis ◽  
Electrophilic Fluorination

Electrophilic fluorination of stereodefined disubstituted silyl ketene hemiaminals en route to tertiary α-fluorinated carbonyl derivatives

2018 ◽  
Vol 16 (7) ◽  
pp. 1079-1082 ◽  
Author(s):  
Jian Qiang Huang ◽  
Zackaria Nairoukh ◽  
Ilan Marek
Keyword(s):  
Carbonyl Compounds ◽  
Diastereoselective Synthesis ◽  
Carbonyl Derivatives ◽  
Electrophilic Fluorination

A highly diastereoselective synthesis of tertiary α-fluoro carbonyl compounds is reported in only two chemical steps from a simple alkyne through the reaction of stereodefined fully substituted silyl ketene hemiaminal derivatives with Selectfluor.

Enantioselective and diastereoselective synthesis of fluorinated dipeptides by late electrophilic fluorination

2005 ◽  
Vol 46 (30) ◽  
pp. 5029-5031 ◽  
Author(s):  
Barbara Mohar ◽  
Damjan Sterk ◽  
Laurent Ferron ◽  
Dominique Cahard
Keyword(s):  
Diastereoselective Synthesis ◽  
Electrophilic Fluorination

Naturally Occurring Organic Acid-catalyzed Facile Diastereoselective Synthesis of Biologically Active (E)-3-(arylimino)indolin-2-one Derivatives in Water at Room Temperature

2019 ◽  
Vol 23 (16) ◽  
pp. 1778-1788 ◽  
Author(s):  
Gurpreet Kaur ◽  
Arvind Singh ◽  
Kiran Bala ◽  
Mamta Devi ◽  
Anjana Kumari ◽  
...  
Keyword(s):  
Room Temperature ◽  
Biologically Active ◽  
Environmentally Benign ◽  
Diastereoselective Synthesis ◽  
Substituted Anilines ◽  
Reaction Conditions ◽  
Naturally Occurring ◽  
Acid Catalyzed ◽  
Reaction Media ◽  
Column Chromatographic

A simple, straightforward and efficient method has been developed for the synthesis of (E)-3-(arylimino)indolin-2-one derivatives and (E)-2-((4-methoxyphenyl)imino)- acenaphthylen-1(2H)-one. The synthesis of these biologically-significant scaffolds was achieved from the reactions of various substituted anilines and isatins or acenaphthaquinone, respectively, using commercially available, environmentally benign and naturally occurring organic acids such as mandelic acid or itaconic acid as catalyst in aqueous medium at room temperature. Mild reaction conditions, energy efficiency, good to excellent yields, environmentally benign conditions, easy isolation of products, no need of column chromatographic separation and the reusability of reaction media are some of the significant features of the present protocol.

Diastereoselective Synthesis of Novel Optically Active Five Membered O- and N-heterocyclic Compounds

2012 ◽  
Vol 9 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Ervin Kovacs ◽  
Ferenc Farkas ◽  
Angelika Thurner ◽  
Aron Szollosy ◽  
Ferenc Faigl
Keyword(s):  
Heterocyclic Compounds ◽  
Optically Active ◽  
Diastereoselective Synthesis
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