Ultrasound-Irradiated Michael Addition of Amines to Ferrocenylenones under Solvent-Free and Catalyst-Free Conditions at Room Temperature.

ChemInform ◽  
2005 ◽  
Vol 36 (44) ◽  
Author(s):  
Jin-Ming Yang ◽  
Shun-Jun Ji ◽  
Da-Gong Gu ◽  
Zhi-Liang Shen ◽  
Shun-Yi Wang
Keyword(s):  
Michael Addition ◽  
Room Temperature ◽  
Solvent Free ◽  
Catalyst Free

Ultrasound-irradiated Michael addition of amines to ferrocenylenones under solvent-free and catalyst-free conditions at room temperature

2005 ◽  
Vol 690 (12) ◽  
pp. 2989-2995 ◽  
Author(s):  
Jin-Ming Yang ◽  
Shun-Jun Ji ◽  
Da-Gong Gu ◽  
Zhi-Liang Shen ◽  
Shun-Yi Wang
Keyword(s):  
Michael Addition ◽  
Room Temperature ◽  
Solvent Free ◽  
Catalyst Free

Efficient Synthesis of Novel Quinolinone Derivatives via Catalyst-free Multicomponent Reaction

2020 ◽  
Vol 17 (5) ◽  
pp. 403-407
Author(s):  
Rui Du ◽  
Liangliang Han ◽  
Zhongqiang Zhou ◽  
Victor Borovkov
Keyword(s):  
Reaction Time ◽  
Multicomponent Reaction ◽  
Room Temperature ◽  
Reaction Rates ◽  
Solvent Free ◽  
Hydroxyl Group ◽  
Efficient Synthesis ◽  
Catalyst Free ◽  
Solvent Free Conditions ◽  
Substituted Benzaldehydes

The synthesis of 3-(aryl(piperidin-1-yl)methyl)-4-hydroxyquinolin-2(1H)-one derivatives via catalyst-free multicomponent reaction is described. The reaction of 4-hydroxyquinolin-2(1H)-one, piperidine, and 4-chlorobenzaldehyde was carried out in different solvents and under solvent-free conditions at room temperature. The best solvent in terms of the yield and reaction time was found to be dichloromethane. Most substituted benzaldehydes reacted with 4-hydroxyquinolin-2(1H)-one and piperidine to afford corresponding products in good-to-excellent yields. Aldehydes with electronwithdrawing groups were more reactive to exhibit higher reaction rates. However, 2-substituted benzaldehydes did not react with 4-hydroxyquinolin-2(1H)-one and piperidine under the reaction condition. Aldehydes bearing a hydroxyl group failed to produce the corresponding products.

A green and clean pathway: one pot, multicomponent, and visible light assisted synthesis of pyrano[2,3-c]pyrazoles under catalyst-free and solvent-free conditions

2017 ◽  
Vol 41 (19) ◽  
pp. 11148-11154 ◽  
Author(s):  
Bhartendu Pati Tripathi ◽  
Anu Mishra ◽  
Pratibha Rai ◽  
Yogesh Kumar Pandey ◽  
Madhulika Srivastava ◽  
...  
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Free ◽  
Solvent Free Conditions

Visible light mediated, an eco-friendlier synthetic protocol for dihydropyrano[2,3-c]pyrazoles via catalyst-free and solvent-free conditions at room temperature.

Michael Addition of Aryl Thiols to 3-(2,2,2-Trifluoroethylidene)Oxindoles under Catalyst-Free Conditions: The Rapid Synthesis of Sulfur-Containing Oxindole Derivatives

2018 ◽  
Vol 42 (4) ◽  
pp. 210-214
Author(s):  
Bo Chen ◽  
Jiaheng Lei ◽  
Junling Zhao
Keyword(s):  
Michael Addition ◽  
Room Temperature ◽  
Rapid Synthesis ◽  
Efficient Catalyst ◽  
Mild Conditions ◽  
Catalyst Free ◽  
Wide Range ◽  
High Yields ◽  
The Michael Addition ◽  
Sulfur Containing

A mild and efficient catalyst-free method for the rapid synthesis at room temperature of 3-thiomethylated oxindole derivatives has been achieved via the Michael addition of aryl thiols to ring and 1-substituted 3-(2,2,2-trifluoroethylidene)oxindoles in dichloromethane. The method was applicable to a wide range of thiols and variously substituted 3-(2,2,2-trifluoroethylidene)oxindoles under mild conditions as demonstrated by the synthesis in high yields with good diastereoselectivities of 30 3-thiomethylated oxindoles bearing a trifluoromethyl group.

Catalyst-Free Room-Temperature Self-Healing Polymer Networks Based on Dynamic Covalent Quinone Methide-Secondary Amine Chemistry

2021 ◽  
Author(s):  
Yuanxing Zhang ◽  
Ying Wu ◽  
Jiayi Li ◽  
Ke Zhang
Keyword(s):  
Secondary Amine ◽  
Michael Addition ◽  
Room Temperature ◽  
Polymer Networks ◽  
Quinone Methide ◽  
Self Healing ◽  
Ambient Conditions ◽  
Catalyst Free ◽  
External Stimuli

An aza-Michael addition between 2,6-di-t-butyl-7-phenyl-p-quinone methide and secondary amine was demonstrated to hold the dynamic covalent reaction property under ambient conditions requiring no external stimuli. Based on this dynamic covalent...

A Rapid and Green Synthesis of 8-Aryl-5,7,7-tricyanoisoquinoline Derivatives at Room Temperature under Solvent-Free and Catalyst-Free Conditions

2016 ◽  
Vol 36 (7) ◽  
pp. 1706
Author(s):  
Yanian Gao ◽  
Mengye Zhang ◽  
Haiyan Qian ◽  
Qianwen Xie ◽  
Ming Chen ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Room Temperature ◽  
Solvent Free ◽  
Catalyst Free

Diversity oriented catalyst-free and solvent-free one-pot MCR at room temperature: rapid and regioselective convergent approach to highly functionalized dihydro-4H-thiopyrans

Tetrahedron ◽  
2013 ◽  
Vol 69 (37) ◽  
pp. 8013-8018 ◽  
Author(s):  
Suvajit Koley ◽  
Sushobhan Chowdhury ◽  
Tanmoy Chanda ◽  
B. Janaki Ramulu ◽  
Maya Shankar Singh
Keyword(s):  
Room Temperature ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Free ◽  
Convergent Approach

Catalyst-Free One-Pot Synthesis of Chromeno-Imidazo-Pyridinones by an Aza-Michael Addition/Rearrangement/Heterocyclization Tandem Reaction

Synlett ◽  
2018 ◽  
Vol 29 (11) ◽  
pp. 1437-1440 ◽  
Author(s):  
Oualid Talhi ◽  
Norah Bennamane ◽  
Artur Silva ◽  
Houria Lakhdari ◽  
Ridha Hassaine ◽  
...  
Keyword(s):  
Michael Addition ◽  
Room Temperature ◽  
Addition Reaction ◽  
2D Nmr ◽  
X Ray Diffraction ◽  
One Pot ◽  
X Ray ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
New Compounds

A one-pot synthesis of a novel series of chromeno-imidazo-pyridinone derivatives from 3-[(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl]chromones and ethane-1,2-diamine at room temperature under catalyst-free conditions has been successfully developed. This approach involves a tandem aza-Michael addition reaction, a chromone-to-chromanone rearrangement, and a heterocyclization sequence, leading to chromeno-imidazo-pyridinone polyheterocycles. The structure and absolute configurations of the new compounds were elucidated by a combination of 1D- and 2D-NMR analyses and single-crystal X-ray diffraction.

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