From 4,5,6,7-Tetrahydro-5-methylimidazo [4,5,1-jk](1,4)benzodiazepin-2(1H)-one (TIBO) to Etravirine (TMC125): Fifteen Years of Research on Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase

ChemInform ◽  
2005 ◽  
Vol 36 (26) ◽  
Author(s):  
Bart L. De Corte
Keyword(s):  
Reverse Transcriptase ◽  
Nucleoside Inhibitors ◽  
Hiv 1

Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors

1996 ◽  
Vol 39 (8) ◽  
pp. 1589-1600 ◽  
Author(s):  
Andrew L. Hopkins ◽  
Jingshan Ren ◽  
Robert M. Esnouf ◽  
Benjamin E. Willcox ◽  
E. Yvonne Jones ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Conformational Changes ◽  
Nucleoside Inhibitors ◽  
Hiv 1

scholarly journals Unbinding Dynamics of Non-Nucleoside Inhibitors from HIV-1 Reverse Transcriptase

2018 ◽  
Vol 123 (8) ◽  
pp. 1741-1748 ◽  
Author(s):  
Leela S. Dodda ◽  
Julian Tirado-Rives ◽  
William L. Jorgensen
Keyword(s):  
Reverse Transcriptase ◽  
Nucleoside Inhibitors ◽  
Hiv 1

HIV-1 reverse transcriptase connection subdomain mutations involved in resistance to approved non-nucleoside inhibitors

2011 ◽  
Vol 92 (2) ◽  
pp. 139-149 ◽  
Author(s):  
Luis Menéndez-Arias ◽  
Gilberto Betancor ◽  
Tania Matamoros
Keyword(s):  
Reverse Transcriptase ◽  
Nucleoside Inhibitors ◽  
Hiv 1

scholarly journals Global Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors

Biology ◽  
2012 ◽  
Vol 1 (2) ◽  
pp. 222-244 ◽  
Author(s):  
David W. Wright ◽  
Benjamin A. Hall ◽  
Paul Kellam ◽  
Peter V. Coveney
Keyword(s):  
Reverse Transcriptase ◽  
Conformational Dynamics ◽  
Nucleoside Inhibitors ◽  
Hiv 1
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