A Convenient One-Pot Synthesis of Asymmetric 1,3,5-Triazine-2,4,6-triones and Its Application Towards a Novel Class of Gonadotropin-Releasing Hormone Receptor Antagonists.

ChemInform ◽  
2005 ◽  
Vol 36 (25) ◽  
Author(s):  
Zhiqiang Guo ◽  
Dongpei Wu ◽  
Yun-Fei Zhu ◽  
Fabio C. Tucci ◽  
Joseph Pontillo ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Receptor Antagonists ◽  
One Pot ◽  
Releasing Hormone ◽  
One Pot Synthesis ◽  
Gonadotropin Releasing Hormone Receptor

Allosteric and Orthosteric Binding Modes of Two Nonpeptide Human Gonadotropin-Releasing Hormone Receptor Antagonists

Biochemistry ◽  
2006 ◽  
Vol 45 (51) ◽  
pp. 15327-15337 ◽  
Author(s):  
Susan K. Sullivan ◽  
Michael S. Brown ◽  
Yinghong Gao ◽  
Colin J. Loweth ◽  
Francisco M. Lio ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Binding Modes ◽  
Receptor Antagonists ◽  
Releasing Hormone ◽  
Gonadotropin Releasing Hormone Receptor

Identification of 1-Arylmethyl-3- (2-aminoethyl)-5-aryluracil as Novel Gonadotropin-Releasing Hormone Receptor Antagonists

2003 ◽  
Vol 46 (11) ◽  
pp. 2023-2026 ◽  
Author(s):  
Yun-Fei Zhu ◽  
Timothy D. Gross ◽  
Zhiqiang Guo ◽  
Patrick J. Connors, ◽  
Yinghong Gao ◽  
...  
Keyword(s):  
Hormone Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Receptor Antagonists ◽  
Releasing Hormone ◽  
Gonadotropin Releasing Hormone Receptor

Non-Peptide Gonadotropin-Releasing Hormone Receptor Antagonists

2008 ◽  
Vol 51 (12) ◽  
pp. 3331-3348 ◽  
Author(s):  
Stephen F. Betz ◽  
Yun-Fei Zhu ◽  
Chen Chen ◽  
R. Scott Struthers
Keyword(s):  
Hormone Receptor ◽  
Gonadotropin Releasing Hormone ◽  
Receptor Antagonists ◽  
Releasing Hormone ◽  
Gonadotropin Releasing Hormone Receptor
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