Copper(II) Triflate Immobilized in [bmin]BF4 Ionic Liquid: An Efficient Reaction Medium for Michael Addition of β-Ketoesters to Acceptor-Activated Alkenes.

ChemInform ◽  
2005 ◽  
Vol 36 (24) ◽  
Author(s):  
J. S. Yadav ◽  
B. V. S. Reddy ◽  
Gakul Baishya ◽  
A. Venkat Narsaiah
Keyword(s):  
Ionic Liquid ◽  
Michael Addition ◽  
Reaction Medium

Tandem reaction of Morita–Baylis–Hillman alcohols derived from acrylic nitrile with 2-aminobenzimidazole in ionic liquid [BMIM]Cl/H2O

2012 ◽  
Vol 90 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Yan Wang ◽  
Li Liu ◽  
Dong Wang ◽  
Yong-Jun Chen
Keyword(s):  
Ionic Liquid ◽  
Michael Addition ◽  
Cyano Group ◽  
Reaction Medium ◽  
Tandem Reaction ◽  
Amino Group ◽  
Efficient Synthesis ◽  
One Pot ◽  
Imine Compounds

The tandem reaction of Morita–Baylis–Hillman (MBH) alcohols 1a–1l derived from acrylic nitrile with 2-aminobenzimidazole (2) in ionic iquid (IL) [BMIM]Cl/H2O without additional catalyst was developed for the efficient synthesis of benzimidazol[1,2-a]pyrimidin-7(8H)-imine compounds. The tandem reaction included aza-Michael addition and intramolecular addition of an amino group to the cyano group in one pot. The combination of ionic liquid and water was found to be the best reaction medium, which played a role for accelerating the tandem reaction.

Lipase-Catalyzed Acyl-L-Carnitines Synthesis in [Bmim]PF6 Ionic Liquid

2009 ◽  
Vol 5 (1) ◽  
Author(s):  
Jin-qiang Tian ◽  
Qiang Wang ◽  
Zhong-yuan Zhang
Keyword(s):  
Ionic Liquid ◽  
Lipase Activity ◽  
Molecular Sieves ◽  
Reaction Medium ◽  
Molar Ratio ◽  
Reaction Conditions ◽  
Optimal Reaction ◽  
Better Than

In order to significantly improve the biosynthesis of acyl-L-carnitines catalyzed by lipase, there must be an efficient and suitable reaction medium that is not only polar but also hydrophobic. [Bmim]PF6, which satisfies the above two requirements, was applied as the medium. The optimal reaction conditions were: for isovaleryl-L-carnitine, 0.22aW, 200mg molecular sieves, 60ºC, 4:1 of molar ratio (fatty acid:L-carnitine), 150rpm and 60h; for octanoyl-L-carnitine and palmitoyl-L-carnitine, 0.22aW, 250 mg molecular sieves, 5:1 of molar ratio (fatty acid:L-carnitine), 200rpm, 48h, 60ºC (octanoyl-L-carnitine) and 65ºC (palmitoyl-L-carnitine). Their overall yields could reach 59.14%, 90.79% and 98.03%, respectively. The yields of isovaleryl-L-carnitine, octanoyl-L-carnitine and palmitoyl-L-carnitine in [Bmim]PF6 were 16.21%, 73.67% and 44.22 % more than those in acetonitrile, respectively. [Bmim]PF6 as the medium was better than acetonitrile. It could not only enhance the yields of acyl-L-carnitines, but also protect the lipase activity.

ChemInform Abstract: N-Benzyloxycarbonylation of Amines in the Ionic Liquid [TPA][L-Pro] as an Efficient Reaction Medium.

ChemInform ◽  
2008 ◽  
Vol 39 (31) ◽  
Author(s):  
N. Suryakiran ◽  
K. Chinni Mahesh ◽  
D. Ramesh ◽  
J. Jon Paul Selvam ◽  
Y. Venkateswarlu
Keyword(s):  
Ionic Liquid ◽  
Reaction Medium
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