Ti(III)-Induced Radical Cyclization. A Stereoselective Entry to the Perhydrobenzo[e]indene Unit of New Protein Farnesyltransferase Inhibitors, Andrastins A?D.

Masahiro Toyota; Rei Okamoto; Takeshi Ogata; Masataka Ihara

doi:10.1002/chin.200515167

Ti(III)-Induced Radical Cyclization. A Stereoselective Entry to the Perhydrobenzo[e]indene Unit of New Protein Farnesyltransferase Inhibitors, Andrastins A?D.

ChemInform ◽

10.1002/chin.200515167 ◽

2005 ◽

Vol 36 (15) ◽

Author(s):

Masahiro Toyota ◽

Rei Okamoto ◽

Takeshi Ogata ◽

Masataka Ihara

Keyword(s):

Radical Cyclization ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

New Protein

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Ti(III)-induced radical cyclization. A stereoselective entry to the perhydrobenzo[e]indene unit of new protein farnesyltransferase inhibitors, andrastins A–D

Tetrahedron Letters ◽

10.1016/j.tetlet.2004.10.075 ◽

2004 ◽

Vol 45 (50) ◽

pp. 9203-9205 ◽

Cited By ~ 5

Author(s):

Masahiro Toyota ◽

Rei Okamoto ◽

Takeshi Ogata ◽

Masataka Ihara

Keyword(s):

Radical Cyclization ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

New Protein

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New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.3109/14756366.2011.643302 ◽

2012 ◽

Vol 28 (1) ◽

pp. 163-171 ◽

Cited By ~ 25

Author(s):

Sébastien Lethu ◽

Damien Bosc ◽

Elisabeth Mouray ◽

Philippe Grellier ◽

Joëlle Dubois

Keyword(s):

Carboxylic Acid ◽

Solid Phase Synthesis ◽

Solid Phase ◽

Farnesyltransferase Inhibitors ◽

Phase Synthesis ◽

Protein Farnesyltransferase ◽

New Protein

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Kurasoins A and B, New Protein Farnesyltransferase Inhibitors Produced by Paecilomyces sp. FO-3684. II. Structure Elucidation and Total Synthesis.

The Journal of Antibiotics ◽

10.7164/antibiotics.49.886 ◽

1996 ◽

Vol 49 (9) ◽

pp. 886-889 ◽

Cited By ~ 29

Author(s):

RYUJI UCHIDA ◽

KAZURO SHIOMI ◽

TOSHIAKI SUNAZUKA ◽

JUNJI INOKOSHI ◽

AI NISHIZAWA ◽

...

Keyword(s):

Total Synthesis ◽

Structure Elucidation ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

New Protein

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ChemInform Abstract: Kurasoins A and B, New Protein Farnesyltransferase Inhibitors Produced by Paecilomyces sp. FO-3684. Part 1. Producing Strain, Fermentation, Isolation, and Biological Activities.

ChemInform ◽

10.1002/chin.199712233 ◽

2010 ◽

Vol 28 (12) ◽

pp. no-no

Author(s):

R. UCHIDA ◽

K. SHIOMI ◽

J. INOKOSHI ◽

R. MASUMA ◽

T. KAWAKUBO ◽

...

Keyword(s):

Biological Activities ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

New Protein

Download Full-text

Kurasoins A and B, New Protein Farnesyltransferase Inhibitors Produced by Paecilomyces sp. FO-3684. I. Producing Strain, Fermentation, Isolation, and Biological Activities.

The Journal of Antibiotics ◽

10.7164/antibiotics.49.932 ◽

1996 ◽

Vol 49 (9) ◽

pp. 932-934 ◽

Cited By ~ 29

Author(s):

RYUJI UCHIDA ◽

KAZURO SHIOMI ◽

JUNJI INOKOSHI ◽

ROKURO MASUMA ◽

TOMOYA KAWAKUBO ◽

...

Keyword(s):

Biological Activities ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

New Protein

Download Full-text

ChemInform Abstract: Andrastins A ≅ C, New Protein Farnesyltransferase Inhibitors Produced by Penicillium sp. FO-3929. Part 1. Producing Strain, Fermentation, Isolation, and Biological Activities.

ChemInform ◽

10.1002/chin.199643174 ◽

2010 ◽

Vol 27 (43) ◽

pp. no-no

Author(s):

S. OMURA ◽

J. INOKOSHI ◽

R. UCHIDA ◽

K. SHIOMI ◽

R. MASUMA ◽

...

Keyword(s):

Biological Activities ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

Penicillium Sp ◽

New Protein

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Andrastins A-C, New Protein Farnesyltransferase Inhibitors Produced by Penicillium sp. FO-3929. I. Producing Strain, Fermentation, Isolation, and Biological Activities.

The Journal of Antibiotics ◽

10.7164/antibiotics.49.414 ◽

1996 ◽

Vol 49 (5) ◽

pp. 414-417 ◽

Cited By ~ 36

Author(s):

SATOSHI OMURA ◽

JUNJI INOKOSHI ◽

RYUJI UCHIDA ◽

KAZURO SHIOMI ◽

ROKURO MASUMA ◽

...

Keyword(s):

Biological Activities ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

Penicillium Sp ◽

New Protein

Download Full-text

Andrastins A∼C, new protein farnesyltransferase inhibitors, produced by Penicillium sp. FO-3929

Tetrahedron Letters ◽

10.1016/0040-4039(95)02412-3 ◽

1996 ◽

Vol 37 (8) ◽

pp. 1265-1268 ◽

Cited By ~ 41

Author(s):

Kazuro Shiomi ◽

Ryuji Uchida ◽

Junji Inokoshi ◽

Haruo Tanaka ◽

Yuzuru Iwai ◽

...

Keyword(s):

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

Penicillium Sp ◽

New Protein

Download Full-text

ChemInform Abstract: Andrastins A ≅ C, New Protein Farnesyltransferase Inhibitors Produced by Penicillium sp. FO-3929. Part 2. Structure Elucidation and Biosynthesis.

ChemInform ◽

10.1002/chin.199643175 ◽

2010 ◽

Vol 27 (43) ◽

pp. no-no

Author(s):

R. UCHIDA ◽

K. SHIOMI ◽

J. INOKOSHI ◽

T. SUNAZUKA ◽

H. TANAKA ◽

...

Keyword(s):

Structure Elucidation ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

Penicillium Sp ◽

New Protein

Download Full-text

ChemInform Abstract: Kurasoins A and B, New Protein Farnesyltransferase Inhibitors Produced by Paecilomyces sp. FO-3684. Part 2. Structure Elucidation and Total Synthesis.

ChemInform ◽

10.1002/chin.199712229 ◽

2010 ◽

Vol 28 (12) ◽

pp. no-no

Author(s):

R. UCHIDA ◽

K. SHIOMI ◽

T. SUNAZUKA ◽

J. INOKOSHI ◽

A. NISHIZAWA ◽

...

Keyword(s):

Total Synthesis ◽

Structure Elucidation ◽

Farnesyltransferase Inhibitors ◽

Protein Farnesyltransferase ◽

New Protein

Download Full-text