Synthesis and Cytotoxic Activity of Halogenodinitromethyl Derivatives of 1,3,5-Triazine (I).

ChemInform ◽  
2005 ◽  
Vol 36 (3) ◽  
Author(s):  
A. A. Gidaspov ◽  
V. V. Bakharev ◽  
E. V. Kachanovskaya ◽  
E. A. Kosareva ◽  
M. V. Galkina ◽  
...  
2013 ◽  
Vol 66 ◽  
pp. 388-399 ◽  
Author(s):  
Aziz Shahrisa ◽  
Somayeh Esmati ◽  
Ramin Miri ◽  
Omidreza Firuzi ◽  
Najmeh Edraki ◽  
...  

2014 ◽  
Vol 12 (12) ◽  
pp. 929-936 ◽  
Author(s):  
De-Biao YAN ◽  
Dong-Ping ZHANG ◽  
Ming LI ◽  
Wen-Yuan LIU ◽  
Feng FENG ◽  
...  

ChemInform ◽  
2010 ◽  
Vol 31 (17) ◽  
pp. no-no
Author(s):  
Abdelhakim Elomri ◽  
Sylvie Michel ◽  
Michel Koch ◽  
Elisabeth Seguin ◽  
Francois Tillequin ◽  
...  

2013 ◽  
Vol 57 ◽  
pp. 265-272 ◽  
Author(s):  
F.T.G.S. Cardozo ◽  
C.M. Camelini ◽  
M.N.S. Cordeiro ◽  
A. Mascarello ◽  
B.G. Malagoli ◽  
...  

Author(s):  
Ishwar Bhat K ◽  
Abhishek Kumar

Objective: Many derivatives of pyrimidine are known for the broad-spectrum biological activities such as antimicrobial, antitumor, antibacterial, antitubercular, anti-inflammatory, and cytotoxic activity. Chalcones with an enone group show potent pharmacological activities such as antiinflammatory, antibacterial, antifungal, and antimalarial activity. A series of pyrimidines from chalcones have been synthesized and screened for anti-inflammatory and cytotoxic activity studies.Methods: Chalcones [1-(4-nitrophenyl)-3-substituted-phenylprop-2-en-1-one] were synthesized from various substituted aldehydes with 4-nitroacetophenone and cyclized with urea and glacial acetic acid to give pyrimidine derivatives [4-(4-nitrophenyl)-6-substituted-phenylpyrimidin-2-ol].Results: Anti-inflammatory and cytotoxic activity studies revealed that some of the synthesized compounds have shown significant activity.Conclusion: The observed results proved that pyrimidines are found to be interesting lead molecules for the synthesis of anti-inflammatory and cytotoxic agents


2020 ◽  
Vol 132 (1) ◽  
Author(s):  
Venugopalarao Vikram ◽  
Srinivasa R Penumutchu ◽  
Raviraj Vankayala ◽  
Suresh Thangudu ◽  
Karteek Rao Amperayani ◽  
...  

Planta Medica ◽  
1986 ◽  
Vol 52 (06) ◽  
pp. 548-549 ◽  
Author(s):  
P. Piacentini ◽  
R. Cipelli ◽  
E. Zizzi ◽  
G. Gorini ◽  
L. Ciardelli ◽  
...  

Il Farmaco ◽  
2005 ◽  
Vol 60 (6-7) ◽  
pp. 519-527 ◽  
Author(s):  
Jerzy Kossakowski ◽  
Kinga Ostrowska ◽  
Elżbieta Hejchman ◽  
Irena Wolska

Author(s):  
Mohsen Vosooghi ◽  
Hoda Yahyavi ◽  
Kouros Divsalar ◽  
Hashem Shamsa ◽  
Asma Kheirollahi ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document