Studying Chemistry of Heterocyclic Compounds — Some Rearrangement Reactions of Indoles and the Related Compounds

ChemInform ◽  
2005 ◽  
Vol 36 (1) ◽  
Author(s):  
Yutaka Morita
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Marthe Carine Djuidje Fotsing ◽  
Dieudonné Njamen ◽  
Zacharias Tanee Fomum ◽  
Derek Tantoh Ndinteh

Abstract Cyclic and polycyclic compounds containing moieties such as imidazole, pyrazole, isoxazole, thiazoline, oxazine, indole, benzothiazole and benzoxazole benzimidazole are prized molecules because of the various pharmaceutical properties that they display. This led Prof. Landor and co-workers to engage in the synthesis of several of them such as alkylimidazolenes, oxazolines, thiazolines, pyrimidopyrimidines, pyridylpyrazoles, benzoxazines, quinolines, pyrimidobenzimidazoles and pyrimidobenzothiazolones. This review covers the synthesis of biologically active heterocyclic compounds by the Michael addition and the double Michael addition of various amines and diamines on allenic nitriles, acetylenic nitriles, hydroxyacetylenic nitriles, acetylenic acids and acetylenic aldehydes. The heterocycles were obtained in one step reaction and in most cases, did not give side products. A brief discussion on the biological activities of some heterocycles is also provided.


2015 ◽  
Vol 59 (1) ◽  
pp. 16-25 ◽  
Author(s):  
Mercédesz Tőrincsi ◽  
Gábor Hornyánszky ◽  
Pál Kolonits ◽  
Lajos Novák

Heterocycles ◽  
1989 ◽  
Vol 29 (4) ◽  
pp. 815 ◽  
Author(s):  
Geoffrey A. Cordell ◽  
Shinji Funayama

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