Hydroxylamines and Sulfinamide as Amine Components in the Petasis Boronic Acid—Mannich Reaction: Synthesis of N-Hydroxy or Alkoxy-α-aminocarboxylicacids and N-(tert-Butyl sulfinyl)-α-amino Carboxylicacids.

ChemInform ◽  
2004 ◽  
Vol 35 (10) ◽  
Author(s):  
Dinabandhu Naskar ◽  
Amrita Roy ◽  
William L. Seibel ◽  
David E. Portlock
Keyword(s):  
Mannich Reaction ◽  
Boronic Acid ◽  
Reaction Synthesis ◽  
Tert Butyl

Construction the A-B bicyclic ring structure of Stemocurtisisne

2020 ◽  
Vol 17 ◽  
Author(s):  
Duc Dau Xuan
Keyword(s):  
Glutamic Acid ◽  
Natural Product ◽  
Mannich Reaction ◽  
Boronic Acid ◽  
Ring Opening ◽  
Ring Structure ◽  
Starting Material ◽  
Epoxide Ring ◽  
Epoxide Ring Opening

: The synthesis of the A-B bicyclic ring structure 3 of the natural product Stemocurtisine is described. The synthesis was accomplished in seven synthetic steps from commercially available L-glutamic acid. The key step involved a borono-Mannich reaction between the hemiaminal 6 and trans-β-styryl boronic acid and trans-β-styrylpotassiumtrifluoroborate to prepare the cis diene 4. Attempts to prepare the A-B-C ring compound 2 via intramolecular epoxide ring opening followed by rearangement under different basic conditions were unsuccessful. Only unreactive starting material was recovered.

scholarly journals Tandem intramolecular cyclisation/1,3-aryl shift in N-(4,4-diethoxybutyl)-1-arylmethanimines (Kazan reaction): synthesis of 3-benzylidene-1-pyrrolines

RSC Advances ◽  
2017 ◽  
Vol 7 (80) ◽  
pp. 50955-50960 ◽  
Author(s):  
A. V. Smolobochkin ◽  
A. S. Gazizov ◽  
A. S. Melyashova ◽  
J. K. Voronina ◽  
A. G. Strelnik ◽  
...  
Keyword(s):  
Mannich Reaction ◽  
Sigmatropic Rearrangement ◽  
Tandem Reaction ◽  
Reaction Synthesis ◽  
Aryl Fragment

A novel tandem reaction, which transforms N-(4,4-diethoxybutyl)imines to 3-arylidene-1-pyrrolines via intramolecular Mannich reaction/[1,3]-sigmatropic rearrangement of the aryl fragment is described.

scholarly journals Asymmetric Mannich Reaction: Synthesis of Novel Chiral 5-(substituted aryl)-1,3,4-Thiadiazole Derivatives with Anti-Plant-Virus Potency

2019 ◽  
Vol 25 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Song Bai ◽  
Yunying Zhu ◽  
Qin Wu
Keyword(s):  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Mannich Reaction ◽  
Plant Virus ◽  
Enantiomeric Excess ◽  
Cinchona Alkaloid ◽  
Reaction Synthesis ◽  
Thiadiazole Derivatives

AbstractA series of novel chiral 5-(substituted aryl)-1,3,4-thiadiazole derivatives was synthesized in an enantioselective three-component Mannich reaction using cinchona alkaloid squaramide catalyst with excellent enantioselectivities (up to >99% enantiomeric excess (ee)). The bioassay results showed that these derivatives possessed good to excellent activities against tobacco mosaic virus (TMV).

C8-selective biomimetic transformation of 5,7-dihydroxylated flavonoids by an acid-catalysed phenolic Mannich reaction: Synthesis of flavonoid alkaloids with quercetin and (–)-epicatechin skeletons

Tetrahedron ◽  
2017 ◽  
Vol 73 (11) ◽  
pp. 1503-1510 ◽  
Author(s):  
Viktor Ilkei ◽  
András Spaits ◽  
Anita Prechl ◽  
Judit Müller ◽  
Árpád Könczöl ◽  
...  
Keyword(s):  
Mannich Reaction ◽  
Reaction Synthesis

ChemInform Abstract: Utilization of Aminophosphonates in the Petasis Boronic Acid Mannich Reaction.

ChemInform ◽  
2010 ◽  
Vol 41 (19) ◽  
Author(s):  
Michael V. Shevchuk ◽  
Alexander E. Sorochinsky ◽  
Volodymyr P. Khilya ◽  
Vadim D. Romanenko ◽  
Valery P. Kukhar
Keyword(s):  
Mannich Reaction ◽  
Boronic Acid

ChemInform Abstract: The Boronic Acid Mannich Reaction in Alkaloid Synthesis

ChemInform ◽  
2013 ◽  
Vol 44 (43) ◽  
pp. no-no
Author(s):  
Stephen G. Pyne ◽  
Andrew S. Davis ◽  
Thunwadee Ritthiwigrom ◽  
Christopher W. G. Au ◽  
Kongdech Savaspun ◽  
...  
Keyword(s):  
Mannich Reaction ◽  
Boronic Acid ◽  
Alkaloid Synthesis

Fe(ClO4 )3 ⋅xH2 O-Catalysed Ritter Reaction: Synthesis of N -tert -Butyl Amides from Nitriles and Di-tert -Butyl Dicarbonate

2018 ◽  
Vol 3 (29) ◽  
pp. 8501-8504 ◽  
Author(s):  
Chengliang Feng ◽  
Bin Yan ◽  
Wenjin Yao ◽  
Junqing Chen ◽  
Min Ji
Keyword(s):  
Ritter Reaction ◽  
Reaction Synthesis ◽  
Tert Butyl
Sign in / Sign up

Export Citation Format

Share Document