Microwave-Assisted Rapid and Selective Synthesis of cis- and trans-2,4,5-Triarylimidazolines from Aromatic Aldehydes.

ChemInform ◽  
2003 ◽  
Vol 34 (41) ◽  
Author(s):  
Hitoshi Uchida ◽  
Hirofumi Tanikoshi ◽  
Shuichi Nakamura ◽  
Paidi Yella Reddy ◽  
Takeshi Toru
Keyword(s):  
Aromatic Aldehydes ◽  
Selective Synthesis ◽  
Microwave Assisted ◽  
Cis And Trans

Microwave assisted synthesis of novel Pyrazole derivatives and their biological evaluation as anti-bacterial agents

2020 ◽  
Vol 23 ◽  
Author(s):  
Hadis Khodadad ◽  
Farhad Hatamjafari ◽  
Khalil Pourshamsian ◽  
Babak Sadeghi
Keyword(s):  
Antibacterial Activity ◽  
Aromatic Aldehydes ◽  
Catalytic Amount ◽  
Antibacterial Activities ◽  
Structural Features ◽  
Biological Evaluation ◽  
Aureus Strain ◽  
Microwave Assisted Synthesis ◽  
Pyrazole Derivatives ◽  
Microwave Assisted

Aim and Objective: Microwave-assisted condensation of acetophenone 1 and aromatic aldehydes 2 gave chalcone analogs 3, which were cyclized to pyrazole derivatives 6a-f via the reaction with hydrazine hydrate and oxalic acid in the presence of the catalytic amount of acetic acid in ethanol. Materials and Methods: The structural features of the synthesized compounds were characterized by melting point, FT-IR, 1H, 13C NMR and elemental analysis. Results: The antibacterial activities of the synthesized pyrazoles was evaluated against three gram-positive bacteria such as Enterococcus durans, Staphylococcus aureus, Bacillus subtilis and two gram-negative bacteria such as Escherichia coli and Salmonella typhimurium. Conclusion: All the synthesized pyrazoles showed relatively high antibacterial activity against S. aureus strain and none of them demonstrated antibacterial activity against E. coli.

Selective synthesis of 1,6-anhydro-β-d-mannopyranose and -mannofuranose using microwave-assisted heating

2011 ◽  
Vol 346 (13) ◽  
pp. 1747-1751 ◽  
Author(s):  
Nguyen To Hoai ◽  
Akiyoshi Sasaki ◽  
Masahide Sasaki ◽  
Harumi Kaga ◽  
Toyoji Kakuchi ◽  
...  
Keyword(s):  
Selective Synthesis ◽  
Microwave Assisted

Microwave-Assisted and Ultrasonic-Assisted Three-Component Heterocyclization of 4-Amino-5-carboxamido-1,2,3-triazole, Thiopyran-3-one-1,1-dioxide, and Aromatic Aldehydes

2013 ◽  
Vol 50 (S1) ◽  
pp. E189-E192 ◽  
Author(s):  
Eugene S. Gladkov ◽  
Sergey M. Desenko ◽  
Irina S. Konovalova ◽  
Ulrich Groth ◽  
Oleg V. Shishkin ◽  
...  
Keyword(s):  
Aromatic Aldehydes ◽  
Microwave Assisted ◽  
Ultrasonic Assisted

An easy approach to dihydrochalcones via chalcone in situ hydrogenation

2016 ◽  
Vol 88 (4) ◽  
pp. 349-361 ◽  
Author(s):  
Ana R. Jesus ◽  
Ana P. Marques ◽  
Amélia P. Rauter
Keyword(s):  
Room Temperature ◽  
Aromatic Aldehydes ◽  
Iron Chloride ◽  
High Yield ◽  
Microwave Assisted ◽  
Olefinic Double Bond ◽  
Single Reaction Product ◽  
Very High ◽  
Single Reaction

AbstractDihydrochalcones are polyphenols that exhibit a diversity of bioactivities, namely anti-inflammatory, antimicrobial and antiviral. We have explored the synthetic access to such molecular entities, and describe now an easy and scalable approach based on reduction of the olefinic double bond of chalcone precursors via in situ hydrogenation with the system Et3SiH-Pd/C in very high yield. The intermediate chalcones were synthesized also by a simple and efficient microwave-assisted Claisen–Schmidt condensation of aromatic aldehydes with acetophenones, conveniently protected with ethoxymethyl ether, if required. Chalcones were obtained as single reaction product in high yield in 2–3 h, while under conventional conditions at room temperature the reaction was carried out with completion only after 24 h. In addition, microwave irradiation has proven very efficient for deprotection of ethoxymethyl ether with iron chloride in only 10 min and very high yield.

Microwave-Assisted Selective Synthesis of Mono- and Bistriazines with π-Conjugated Spacers and Study of the Optoelectronic Properties

2014 ◽  
Vol 79 (11) ◽  
pp. 4909-4919 ◽  
Author(s):  
A. Ruiz-Carretero ◽  
O. Noguez ◽  
T. Herrera ◽  
J. R. Ramírez ◽  
A. Sánchez-Migallón ◽  
...  
Keyword(s):  
Optoelectronic Properties ◽  
Selective Synthesis ◽  
Microwave Assisted
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