Regioselective Hydrolysis of Pentaacetyl Catechin and Epicatechin by Porcine Liver Esterase.

ChemInform ◽  
2003 ◽  
Vol 34 (29) ◽  
Author(s):  
Amit Basak ◽  
Subrata Mandal ◽  
Saibal Bandyopadhyay
Keyword(s):  
Porcine Liver ◽  
Liver Esterase ◽  
Hydrolysis Of ◽  
Regioselective Hydrolysis ◽  
Porcine Liver Esterase

scholarly journals Diastereoselective Hydrolysis of Branched Malonate Diesters by Porcine Liver Esterase: Synthesis of 5-Benzyl-Substituted Cα-Methyl-β-proline and Catalytic Evaluation

2017 ◽  
Vol 2017 (20) ◽  
pp. 3009-3016 ◽  
Author(s):  
Hari Kiran Kotapati ◽  
Jamarii D. Robinson ◽  
Daniel R. Lawrence ◽  
Kimberly R. Fortner ◽  
Caleb W. Stanford ◽  
...  
Keyword(s):  
Porcine Liver ◽  
Liver Esterase ◽  
Hydrolysis Of ◽  
Porcine Liver Esterase

Porcine Liver Esterase-Catalyzed Hydrolysis of Methyl Tri-O-acetyl-β-D-arabinopyranoside, Methyl Tri-O-acetyl-β-D-ribopyranoside and Methyl Tri-O-acetyl-β-D-ribofuranoside

2000 ◽  
Vol 65 (10) ◽  
pp. 1619-1629 ◽  
Author(s):  
Jitka Moravcová ◽  
Karel Kefurt ◽  
Romana Hladůvková ◽  
Jan Staněk
Keyword(s):  
Active Site ◽  
Michaelis Constant ◽  
Porcine Liver ◽  
Site Model ◽  
Liver Esterase ◽  
Preparative Yield ◽  
Active Site Model ◽  
Catalyzed Reactions ◽  
Hydrolysis Of ◽  
Porcine Liver Esterase

Methyl 2,3,4-tri-O-acetyl-β-D-arabinopyranoside (1), methyl 2,3,4-tri-O-acetyl-β-D-ribopyranoside (2), and methyl 2,3,5-tri-O-acetyl-β-D-ribofuranoside (3) were deacetylated in porcine liver esterase-catalyzed reactions. Triacetate 1 gave methyl 3,4-di-O-acetyl-β-D-arabinopyranoside in 70% preparative yield while the regioselectivities found for the substrates 2 and 3 were substantially lower. Both the Michaelis constant and maximum rate were calculated for deacetylation of 1, 2, and 3. The results were interpreted using an active site model for the esterase proposed by Jones.

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