Microwave-Assisted Organic Synthesis for Drug Discovery

ChemInform ◽  
2003 ◽  
Vol 34 (14) ◽  
Author(s):  
Michael J. Collins
Keyword(s):  
Drug Discovery ◽  
Organic Synthesis ◽  
Microwave Assisted

Microwave Assisted Organic Synthesis: Cross Coupling and Multicomponent Reactions

2013 ◽  
Vol 17 (5) ◽  
pp. 474-490 ◽  
Author(s):  
Amit Kumar Gupta ◽  
Neetu Singh ◽  
Krishna Nand Singh
Keyword(s):  
Organic Synthesis ◽  
Multicomponent Reactions ◽  
Cross Coupling ◽  
Microwave Assisted

Microwave Assisted Synthesis: A New Technology in Drug Discovery

2009 ◽  
Vol 9 (3) ◽  
pp. 340-358 ◽  
Author(s):  
V. Santagada ◽  
F. Frecentese ◽  
E. Perissutti ◽  
F. Fiorino ◽  
B. Severino ◽  
...  
Keyword(s):  
Drug Discovery ◽  
New Technology ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted

SOMOphilic Alkynylation Using Acetylenic Sulfones as Functional Reagents

2021 ◽  
Author(s):  
Danhua Ge ◽  
Xin Wang ◽  
Xue-Qiang Chu
Keyword(s):  
Drug Discovery ◽  
Organic Synthesis ◽  
Materials Science ◽  
Polymer Chemistry ◽  
The Past ◽  
Acetylenic Sulfones

The past decades have witnessed a boom in alkynylation mainly owing to the importance of alkynyl-containing molecules in organic synthesis, drug discovery, polymer chemistry, and materials science. Besides conventional strategies,...

scholarly journals Cycloaddition of Thiourea- and Guanidine-Substituted Furans to Dienophiles: A Comparison of the Environmentally-Friendly Methods

2020 ◽  
Vol 3 (1) ◽  
pp. 57
Author(s):  
Luka Barešić ◽  
Davor Margetić ◽  
Zoran Glasovac
Keyword(s):  
High Pressure ◽  
Functional Groups ◽  
Organic Synthesis ◽  
High Speed ◽  
Environmentally Friendly ◽  
Microwave Assisted ◽  
Pressure Synthesis ◽  
Ultrasound Assisted ◽  
Substituted Furans ◽  
Guanidine Moiety

The cycloaddition strategy was employed in order to obtain a 7-oxanorbornene framework substituted with a guanidine moiety or its precursor functional groups: protected amine or thiourea. In order to optimize the conditions for the cycloaddition, several environmentally-friendly methods—microwave assisted organic synthesis, high pressure synthesis, high speed vibrational milling, and ultrasound assisted synthesis—were employed. The outcomes of the cycloaddition reactions were interpreted in terms of endo/exo selectivity, the conversion of the reactants to the product, and the isolated yields. In general, our results indicated the HP and HSVM approaches as the methods of choice to give good yields and conversions.

ChemInform Abstract: Microwave Assisted Organic Synthesis

ChemInform ◽  
2010 ◽  
Vol 33 (8) ◽  
pp. no-no
Author(s):  
Pelle Lidstroem ◽  
Jason Tierney ◽  
Bernard Wathey ◽  
Jacob Westman
Keyword(s):  
Organic Synthesis ◽  
Microwave Assisted

scholarly journals Microwave Assisted Synthesis of Organic Compounds and Nanomaterials

2021 ◽  
Author(s):  
Anjali Jha
Keyword(s):  
Green Chemistry ◽  
Organic Synthesis ◽  
Electric Fields ◽  
Chemical Reactions ◽  
Dipole Moments ◽  
Electric Heating ◽  
Microwave Assisted Synthesis ◽  
Microwave Chemistry ◽  
Microwave Assisted ◽  
Promising Area

In the Conventional laboratory or industry heating technique involve Bunsen burner, heating mental/hot plates and electric heating ovens. To produce a variety of useful compounds for betterment of mankind, the Microwave Chemistry was introduced in year 1955 and finds a place in one of the Green chemistry method. In Microwave chemistry is the science of applying microwave radiation to chemical reactions. Microwaves act as high frequency electric fields and will generally heat any material containing mobile electric charges, such as polar molecules in a solvent or conducting ions in a solid. Polar solvents are heated as their component molecules are forced to rotate with the field and lose energy in collisions i.e. the dipole moments of molecules are important in order to proceed with the chemical reactions in this method. It can be termed as microwave-assisted organic synthesis (MAOS), Microwave-Enhanced Chemistry (MEC) or Microwave-organic Reaction Enhancement synthesis (MORE). Microwave-Assisted Syntheses is a promising area of modern Green Chemistry could be adopted to save the earth.

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