ChemInform Abstract: Formal Synthesis of FPA, a Kainoid Amino Acid, via Ketyl Radical Cyclization.

ChemInform ◽  
2010 ◽  
Vol 33 (20) ◽  
pp. no-no
Author(s):  
Mitsuru Kamabe ◽  
Takayuki Miyazaki ◽  
Kimiko Hashimoto ◽  
Haruhisa Shirahama
Keyword(s):  
Amino Acid ◽  
Radical Cyclization ◽  
Ketyl Radical ◽  
Formal Synthesis

Formal Synthesis of FPA, a Kainoid Amino Acid, via Ketyl Radical Cyclization

Heterocycles ◽  
2002 ◽  
Vol 56 (1-2) ◽  
pp. 105 ◽  
Author(s):  
Haruhisa Shirahama ◽  
Mitsuru Kamabe ◽  
Takayuki Miyazaki ◽  
Kimiko Hashimoto
Keyword(s):  
Amino Acid ◽  
Radical Cyclization ◽  
Ketyl Radical ◽  
Formal Synthesis

A new synthetic method for an acromelic acid analog, a potent neuroexcitatory kainoid amino acid, via photoinduced benzyl radical cyclization

2002 ◽  
Vol 43 (43) ◽  
pp. 7777-7780 ◽  
Author(s):  
Satoshi Itadani ◽  
Shigeyuki Takai ◽  
Chieko Tanigawa ◽  
Kimiko Hashimoto ◽  
Haruhisa Shirahama
Keyword(s):  
Amino Acid ◽  
Radical Cyclization ◽  
Synthetic Method ◽  
Benzyl Radical ◽  
Acid Analog

α-Amino Acid Sulfonamides as Versatile Sulfonylation Reagents: Silver-Catalyzed Synthesis of Coumarins and Oxindoles by Radical Cyclization

2018 ◽  
Vol 2018 (43) ◽  
pp. 5905-5909 ◽  
Author(s):  
Kyalo Stephen Kanyiva ◽  
Daisuke Hamada ◽  
Sohei Makino ◽  
Hideaki Takano ◽  
Takanori Shibata
Keyword(s):  
Amino Acid ◽  
Radical Cyclization

scholarly journals Expedient Access to Enantiopure Cyclopentanic Natural Products: Total Synthesis of (-)-Cyclonerodiol

2015 ◽  
Vol 10 (1) ◽  
pp. 1934578X1501000
Author(s):  
Carmen Pérez Morales ◽  
M. Mar Herrador ◽  
José F. Quílez del Moral ◽  
Alejandro F. Barrero
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Radical Cyclization ◽  
Formal Synthesis ◽  
Common Precursor ◽  
Enantiospecific Synthesis ◽  
Optically Pure

Following the principles of collective total synthesis, a number of natural products sharing an optically pure, multifunctional, cyclopentanic core were synthesized from a common precursor: plinol A (1). This intermediate was efficiently obtained in only four steps from (-)-linalool (2) using as the key step a Ti(III)-mediated diastereoselective radical cyclization. The feasibility of this approach was confirmed with the expedient enantiospecific synthesis of cyclonerodiol (3), and the formal synthesis of chocol G (4) and piperitone (5).

ChemInform Abstract: Stereoselective Formal Synthesis of (+)-Allokainic Acid via Thiol-Mediated Acyl Radical Cyclization.

ChemInform ◽  
2011 ◽  
Vol 42 (13) ◽  
pp. no-no
Author(s):  
Ken-ichi Yamada ◽  
Tomohiro Sato ◽  
Masaki Hosoi ◽  
Yasutomo Yamamoto ◽  
Kiyoshi Tomioka
Keyword(s):  
Radical Cyclization ◽  
Acyl Radical ◽  
Formal Synthesis

SmI2-Mediated Couplings of α-Amino Acid Derivatives. Formal Synthesis of (−)-Pumiliotoxin 251D and (±)-Epiquinamide

2013 ◽  
Vol 15 (10) ◽  
pp. 2434-2437 ◽  
Author(s):  
Vagner D. Pinho ◽  
David J. Procter ◽  
Antonio C. B. Burtoloso
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Formal Synthesis

scholarly journals Short Enantioselective Formal Synthesis of (–)-Platencin

Synthesis ◽  
2018 ◽  
Vol 50 (22) ◽  
pp. 4359-4368 ◽  
Author(s):  
Brian Stoltz ◽  
Christian Defieber ◽  
Justin Mohr ◽  
Gennadii Grabovyi
Keyword(s):  
Natural Product ◽  
Radical Cyclization ◽  
Formal Synthesis ◽  
Aldol Cyclization ◽  
Key Steps

A short enantioselective formal synthesis of the antibiotic natural product platencin is reported. Key steps in the synthesis include enantioselective decarboxylation alkylation, aldehyde/olefin radical cyclization, and regioselective aldol cyclization.

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