ChemInform Abstract: Methylated Analogues of Methyl (R)-4-(3,4-Dichlorophenylacetyl)-3- (pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as Highly Potent ϰ-Receptor Agonists: Stereoselective Synthesis, Opioid-Receptor Affinity, Receptor Selecti

Stella Soukara; Christoph A. Maier; Ursula Predoiu; Andreas Ehret; Rolf Jackisch; Bernhard Wuensch

doi:10.1002/chin.200149122

ChemInform Abstract: Methylated Analogues of Methyl (R)-4-(3,4-Dichlorophenylacetyl)-3- (pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as Highly Potent ϰ-Receptor Agonists: Stereoselective Synthesis, Opioid-Receptor Affinity, Receptor Selecti

ChemInform ◽

10.1002/chin.200149122 ◽

2010 ◽

Vol 32 (49) ◽

pp. no-no

Author(s):

Stella Soukara ◽

Christoph A. Maier ◽

Ursula Predoiu ◽

Andreas Ehret ◽

Rolf Jackisch ◽

...

Keyword(s):

Opioid Receptor ◽

Stereoselective Synthesis ◽

Receptor Affinity ◽

Receptor Agonists ◽

Affinity Receptor

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Methylated Analogues of Methyl (R)-4-(3,4-Dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as Highly Potent κ-Receptor Agonists: Stereoselective Synthesis, Opioid-Receptor Affinity, Receptor Selectivity, and Functional Studies

Journal of Medicinal Chemistry ◽

10.1021/jm0108395 ◽

2001 ◽

Vol 44 (17) ◽

pp. 2814-2826 ◽

Cited By ~ 35

Author(s):

Stella Soukara ◽

Christoph A. Maier ◽

Ursula Predoiu ◽

Andreas Ehret ◽

Rolf Jackisch ◽

...

Keyword(s):

Opioid Receptor ◽

Stereoselective Synthesis ◽

Receptor Selectivity ◽

Receptor Affinity ◽

Receptor Agonists ◽

Functional Studies ◽

Affinity Receptor ◽

Κ Receptor

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Promising Therapeutic Agents: Delta Opioid Receptor Agonists

The International Annals of Medicine ◽

10.24087/iam.2017.1.8.252 ◽

2017 ◽

Vol 1 (8) ◽

Author(s):

Amjad Hasan Bazzari ◽

Firas Hasan Bazzari

Keyword(s):

Opioid Receptor ◽

Therapeutic Agents ◽

Delta Opioid Receptor ◽

Receptor Agonists ◽

Opioid Receptor Agonists

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Faculty Opinions recommendation of Abuse potential of biased mu opioid receptor agonists.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734246147.793553258 ◽

2018 ◽

Author(s):

David Taylor

Keyword(s):

Opioid Receptor ◽

Mu Opioid Receptor ◽

Abuse Potential ◽

Mu Opioid ◽

Receptor Agonists ◽

Opioid Receptor Agonists

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Cover Feature: Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid Receptor Agonists (12/2021)

ChemMedChem ◽

10.1002/cmdc.202100380 ◽

2021 ◽

Vol 16 (12) ◽

pp. 1834-1834

Author(s):

Veena D. Yadav ◽

Lalan Kumar ◽

Poonam Kumari ◽

Sakesh Kumar ◽

Maninder Singh ◽

...

Keyword(s):

Opioid Receptor ◽

Kappa Opioid Receptor ◽

Kappa Opioid ◽

Receptor Agonists ◽

Opioid Receptor Agonists

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Conformational Analysis of 6α- and 6β-Naltrexol and Derivatives and Relationship to Opioid Receptor Affinity

Journal of Chemical Information and Modeling ◽

10.1021/ci200405u ◽

2012 ◽

Vol 52 (2) ◽

pp. 391-395 ◽

Cited By ~ 2

Author(s):

Jennifer A. Bayron ◽

Amy M. Deveau ◽

John M. Stubbs

Keyword(s):

Conformational Analysis ◽

Opioid Receptor ◽

Receptor Affinity

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Opioid receptor affinity of multivalent ligand system consisting of polymerized liposome

International journal of peptide & protein research ◽

10.1111/j.1399-3011.1996.tb01111.x ◽

2009 ◽

Vol 48 (1) ◽

pp. 95-101 ◽

Cited By ~ 5

Author(s):

SHOKO TETSUI ◽

JINBAO ZHAO ◽

SHUNSAKU KIMURA ◽

YUKIO IMANISHI

Keyword(s):

Opioid Receptor ◽

Receptor Affinity ◽

Ligand System

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Generalization of NMDA-Receptor Antagonists to the Discriminative Stimulus Effects of κ-Opioid Receptor Agonists U-50,488H, but Not TRK-820 in Rats

Journal of Pharmacological Sciences ◽

10.1254/jphs.scj05006x ◽

2006 ◽

Vol 100 (2) ◽

pp. 157-161 ◽

Cited By ~ 14

Author(s):

Tomohisa Mori ◽

Mutsuko Nomura ◽

Kazumi Yoshizawa ◽

Hiroshi Nagase ◽

Toshiko Sawaguchi ◽

...

Keyword(s):

Nmda Receptor ◽

Opioid Receptor ◽

Discriminative Stimulus ◽

Nmda Receptor Antagonists ◽

Receptor Antagonists ◽

Receptor Agonists ◽

Discriminative Stimulus Effects ◽

Stimulus Effects ◽

Opioid Receptor Agonists

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Mechanisms Responsible for the Enhanced Antinociceptive Effects of μ-Opioid Receptor Agonists in the Rostral Ventromedial Medulla of Male Rats with Persistent Inflammatory Pain

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.107.121954 ◽

2007 ◽

Vol 322 (2) ◽

pp. 813-821 ◽

Cited By ~ 25

Author(s):

Kenneth T. Sykes ◽

Stephanie R. White ◽

Robert W. Hurley ◽

Hirokazu Mizoguchi ◽

Leon F. Tseng ◽

...

Keyword(s):

Opioid Receptor ◽

Inflammatory Pain ◽

Male Rats ◽

Rostral Ventromedial Medulla ◽

Receptor Agonists ◽

Antinociceptive Effects ◽

Ventromedial Medulla ◽

Μ Opioid Receptor ◽

Opioid Receptor Agonists

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The effect of intrathecal opioid-receptor agonists on visceral noxious stimulation in rabbits

Gastroenterology ◽

10.1053/gast.1996.v110.pm8536850 ◽

1996 ◽

Vol 110 (1) ◽

pp. 139-146 ◽

Cited By ~ 16

Author(s):

FM Borgbjerg ◽

C Frigast ◽

JB Madsen ◽

LF Mikkelsen

Keyword(s):

Opioid Receptor ◽

Noxious Stimulation ◽

Receptor Agonists ◽

Opioid Receptor Agonists

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Arylacetamide κ opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.03.020 ◽

2005 ◽

Vol 15 (10) ◽

pp. 2647-2652 ◽

Cited By ~ 11

Author(s):

Bertrand Le Bourdonnec ◽

Christopher W. Ajello ◽

Pamela R. Seida ◽

Roberta G. Susnow ◽

Joel A. Cassel ◽

...

Keyword(s):

Cytochrome P450 ◽

Opioid Receptor ◽

Inhibitory Activity ◽

Cytochrome P450 2D6 ◽

Receptor Agonists ◽

Opioid Receptor Agonists ◽

P450 2D6

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