ChemInform Abstract: Large-Scale Synthesis of a Key Catalytic Reagent for Phosphorus Protection in Building Blocks for Isopolar Phosphonate Oligonucleotide Preparation.

ChemInform ◽  
2001 ◽  
Vol 32 (15) ◽  
pp. no-no
Author(s):  
Dominik Rejman ◽  
Jiri Erbs ◽  
Ivan Rosenberg
Keyword(s):  
Large Scale ◽  
Building Blocks ◽  
Large Scale Synthesis

Orthogonally Protected Monosaccharide Building Blocks for Solid Phase Production of Diversity Oriented Libraries

2010 ◽  
Vol 63 (4) ◽  
pp. 693 ◽  
Author(s):  
Premraj Rajaratnam ◽  
Praveer Gupta ◽  
Peter Katavic ◽  
Krystle Kuipers ◽  
Ngoc Huyh ◽  
...  
Keyword(s):  
Good Yield ◽  
Large Scale ◽  
Solid Phase ◽  
Building Blocks ◽  
Chromatographic Purification ◽  
Large Scale Synthesis ◽  
Phase Production

The large scale synthesis of three orthogonally protected monosaccharide scaffolds suitable for use in the solid phase preparation of large diversity libraries is presented. Scaffolds based on 2-amino-2-deoxy-d-glucopyranose, 2-amino-2-deoxy-d-allopyranose, and 2,4-diamino-2,4-dideoxy-d-galactopyranose were prepared in good yield and with minimal chromatographic purification from commercially available methyl 2-azido-2-deoxy-1-thio-β-d-glucopyranose and methyl 2-amino-2-deoxy-1-thio-β-d-glucopyranose.

Large-Scale Synthesis of New Pyranoid Building Blocks Based on Aldolase-Catalysed Carbon-Carbon Bond Formation

2008 ◽  
Vol 350 (11-12) ◽  
pp. 1751-1759 ◽  
Author(s):  
Michael Wolberg ◽  
Ben H. N. Dassen ◽  
Martin Schürmann ◽  
Stefan Jennewein ◽  
Marcel G. Wubbolts ◽  
...  
Keyword(s):  
Large Scale ◽  
Bond Formation ◽  
Building Blocks ◽  
Carbon Bond ◽  
Carbon Carbon Bond ◽  
Large Scale Synthesis

ChemInform Abstract: Large-Scale Synthesis of New Pyranoid Building Blocks Based on Aldolase-Catalyzed Carbon-Carbon Bond Formation.

ChemInform ◽  
2008 ◽  
Vol 39 (52) ◽  
Author(s):  
Michael Wolberg ◽  
Ben H. N. Dassen ◽  
Martin Schuermann ◽  
Stefan Jennewein ◽  
Marcel G. Wubbolts ◽  
...  
Keyword(s):  
Large Scale ◽  
Bond Formation ◽  
Building Blocks ◽  
Carbon Bond ◽  
Carbon Carbon Bond ◽  
Large Scale Synthesis
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