ChemInform Abstract: HOBt and HOAt-Derived Immonium Salts: New and Highly Efficient Coupling Reagents for Peptide Synthesis.

ChemInform ◽  
2010 ◽  
Vol 31 (19) ◽  
pp. no-no
Author(s):  
Peng Li ◽  
Jie-Cheng Xu
Keyword(s):  
Peptide Synthesis ◽  
Coupling Reagents ◽  
Highly Efficient ◽  
Efficient Coupling

ChemInform Abstract: Sulfonates of N-Triazinylammonium Salts as Highly Efficient, Inexpensive and Environmentally Friendly Coupling Reagents for Peptide Synthesis

ChemInform ◽  
2008 ◽  
Vol 39 (28) ◽  
Author(s):  
Beata Kolesinska ◽  
Justyna Fraczyk ◽  
Giuseppina Sabatino ◽  
Anna M. Papini ◽  
Zbigniew J. Kaminski
Keyword(s):  
Peptide Synthesis ◽  
Environmentally Friendly ◽  
Coupling Reagents ◽  
Highly Efficient

N-Triazinylammonium Tetrafluoroborates. A New Generation of Efficient Coupling Reagents Useful for Peptide Synthesis

2005 ◽  
Vol 127 (48) ◽  
pp. 16912-16920 ◽  
Author(s):  
Zbigniew J. Kamiński ◽  
Beata Kolesińska ◽  
Justyna Kolesińska ◽  
Giuseppina Sabatino ◽  
Mario Chelli ◽  
...  
Keyword(s):  
Peptide Synthesis ◽  
Coupling Reagents ◽  
Efficient Coupling ◽  
New Generation

An improved soluble polynorbornene support for peptide synthesis

RSC Advances ◽  
2015 ◽  
Vol 5 (113) ◽  
pp. 93027-93031
Author(s):  
Nimmashetti Naganna ◽  
Nandita Madhavan
Keyword(s):  
Peptide Synthesis ◽  
Side Chains ◽  
Coupling Reagents

A soluble polynorbornene support containing an oligoether linker as well as alkyl and oligoether side chains has been developed and used to synthesize Leu5-Enkephalin in 52% overall yield using only 1.2 equivalents of coupling reagents.

Synthetic hydroxymethyl-porphyrins for protection of carboxy group

2007 ◽  
Vol 11 (06) ◽  
pp. 434-441 ◽  
Author(s):  
Hitoshi Tamiaki ◽  
Kouji Kumon ◽  
Reiko Shibata
Keyword(s):  
Liquid Phase ◽  
Carboxylic Acid ◽  
Thin Layer ◽  
Peptide Synthesis ◽  
Phenyl Group ◽  
Coupling Reagents ◽  
Protective Groups ◽  
Simple Filtration ◽  
Meso Position ◽  
Layer Chromatography

Hydroxymethyl-porphyrins were prepared by modifying tetraarylporphyrin possessing a p-(methoxycarbonyl)phenyl group at the meso-position and octaethylporphyrin. The synthetic alcohols reacted with carboxylic acids by the use of coupling reagents, to give the corresponding esters quantitatively. Due to the porphyrin dye moiety, the esterification was easily monitored on thin layer chromatography, and the resulting esters were highly soluble in most organic solvents and easily handled. The esters were readily cleaved by the action of an acid to give the original carboxylic acid and hydroxymethyl-porphyrin. Separation of the two species was performed by simple filtration: the carboxylic acid was soluble (filtrate) and the porphyrins were precipitates in methanol. These protective groups for carboxy groups were useful for peptide synthesis in the liquid phase.

Azabenzotriazole (HOAt) derivatives as superior coupling reagents for peptide synthesis

Peptides 1994 ◽  
1995 ◽  
pp. 23-25 ◽  
Author(s):  
F. Albericio ◽  
I. Abdelmoty ◽  
J. M. Bofill ◽  
L. A. Carpino ◽  
A. El-Faham ◽  
...  
Keyword(s):  
Peptide Synthesis ◽  
Coupling Reagents
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