ChemInform Abstract: Derivatives of the Novel Heterocyclic System 1,2,3-Telluradiazine. Synthesis of 2-Aroyl-1,2,3-telluradiazines.

ChemInform ◽  
2010 ◽  
Vol 29 (44) ◽  
pp. no-no
Author(s):  
V. L. NIVOROZHKIN ◽  
I. D. SADEKOV ◽  
V. I. MINKIN
Keyword(s):  
Heterocyclic System ◽  
The Novel ◽  
Derivatives Of

ChemInform Abstract: Synthesis of Derivatives of the Novel Heterocyclic System - Pyrimido(4′ ,5′:4,5)pyrimido(1,2-a)benzimidazole.

ChemInform ◽  
2010 ◽  
Vol 24 (49) ◽  
pp. no-no
Author(s):  
V. A. DOROKHOV ◽  
M. F. GORDEEV ◽  
Z. K. DEM'YANETS ◽  
L. G. VORONTSOVA ◽  
M. G. KURELLA ◽  
...  
Keyword(s):  
Heterocyclic System ◽  
The Novel ◽  
Derivatives Of

scholarly journals Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo

2015 ◽  
Vol 11 ◽  
pp. 481-492 ◽  
Author(s):  
Alireza Shakoori ◽  
John B Bremner ◽  
Mohammed K Abdel-Hamid ◽  
Anthony C Willis ◽  
Rachada Haritakun ◽  
...  
Keyword(s):  
Claisen Rearrangement ◽  
Heterocyclic System ◽  
The Novel ◽  
Ring Closing Metathesis ◽  
One Pot ◽  
Rapid Access ◽  
Directed Synthesis ◽  
Derivatives Of

Diversity-directed synthesis based on the cascade allylation chemistry of indigo, with its embedded 2,2’-diindolic core, has resulted in rapid access to new examples of the hydroxy-8a,13-dihydroazepino[1,2-a:3,4-b']diindol-14(8H)-one skeleton in up to 51% yield. Additionally a derivative of the novel bridged heterocycle 7,8-dihydro-6H-6,8a-epoxyazepino[1,2-a:3,4-b']diindol-14(13H)-one was produced when the olefin of the allylic substrate was terminally disubstituted. Further optimisation also produced viable one-pot syntheses of derivatives of the spiro(indoline-2,9'-pyrido[1,2-a]indol)-3-one (65%) and pyrido[1,2,3-s,t]indolo[1,2-a]azepino[3,4-b]indol-17-one (72%) heterocyclic systems. Ring-closing metathesis of the N,O-diallylic spiro structure and subsequent Claisen rearrangement gave rise to the new (1R,8aS,17aS)-rel-1,2-dihydro-1-vinyl-8H,17H,9H-benz[2',3']pyrrolizino[1',7a':2,3]pyrido[1,2-a]indole-8,17-(2H,9H)-dione heterocyclic system.

Tumor Necrosis Factor-α Production-Enhancing Properties of Novel Adamantylalkylthio Derivatives of Some Heterocyclic Compounds

2005 ◽  
Vol 60 (4) ◽  
pp. 471-475 ◽  
Author(s):  
Barbara Orzeszko ◽  
Tomasz Świtaj ◽  
Anna B. Jakubowska-Mućka ◽  
Witold Lasek ◽  
Andrzej Orzeszko ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Heterocyclic Compounds ◽  
Tumor Necrosis ◽  
The Novel ◽  
Necrosis Factor Alpha ◽  
Tnf Α ◽  
Factor Alpha ◽  
Factor Α ◽  
Derivatives Of ◽  
Necrosis Factor

Certain adamantylated heterocycles were previously shown to enhance the secretion of tumor necrosis factor alpha (TNF-α) by murine melanoma cells that have been transduced with the gene for human TNF-α and constitutively expressed this cytokine. The stimulatory potency of those compounds depended, among other factors, on the structure of the linker between the adamantyl residue and the heterocyclic core. In the present study, a series of (1-adamantyl)alkylsulfanyl derivatives of heterocyclic compounds was prepared by alkylation of the corresponding thioheterocyles. Of the novel adamantylalkylthio compounds tested in the aforementioned cell line, 2-(2-adamantan-1-ylethylsulfanyl)- 4-methyl-pyrimidine was found to be the most active

Thio derivatives of β-diketones and their metal chelates. XIX. Metal chelates of two new fluorinated Monothio-β-diketones and their mass spectra

1975 ◽  
Vol 28 (6) ◽  
pp. 1249 ◽  
Author(s):  
SE Livingstone ◽  
N Saha
Keyword(s):  
Mass Spectra ◽  
Metal Chelates ◽  
The Novel ◽  
Copper Chelates ◽  
Derivatives Of

The nickel(II), palladium(II), platinum(II), copper(II), zinc(II) and rhodium(III) chelates of the new fluorinated monothio-β-diketones RC(SH)=CHCOCF3 (R = Pri, Bui) and the iron(III), ruthenium(III) and cobalt(III) chelates of PriC(SH)=CHCOCF3 have been prepared. The mass spectra of all but the two copper chelates have been obtained. The novel features of the spectra are the occurrence of the ions M-(R-H), M-R, and M-LH and the loss of H2S from the ions M-LH and M-L.

scholarly journals Thermodynamically stable [4 + 2] cycloadducts of lanthanum-encapsulated endohedral metallofullerenes

2014 ◽  
Vol 10 ◽  
pp. 714-721 ◽  
Author(s):  
Yuta Takano ◽  
Yuki Nagashima ◽  
M Ángeles Herranz ◽  
Nazario Martín ◽  
Takeshi Akasaka
Keyword(s):  
Thermal Stability ◽  
Material Science ◽  
Molecular Structures ◽  
Spectroscopic Methods ◽  
Dynamic Nmr ◽  
The Novel ◽  
Endohedral Metallofullerenes ◽  
Derivatives Of ◽  
Paramagnetic Properties

The [4 + 2] cycloaddition of o-quinodimethanes, generated in situ from the sultine 4,5-benzo-3,6-dihydro-1,2-oxathiin 2-oxide and its derivative, to La metal-encapsulated fullerenes, La2@C80 or La@C82, afforded the novel derivatives of endohedral metallofullerenes (3a,b, 4a,b and 5b). Molecular structures of the resulting compounds were elucidated using spectroscopic methods such as MALDI–TOF mass, optical absorption, and NMR spectroscopy. The [4 + 2] adducts of La2@C80 (3a,b, and 4a,b) and La@C82 (5b), respectively, retain diamagnetic and paramagnetic properties, as confirmed by EPR spectroscopy. Dynamic NMR measurements of 4a at various temperatures demonstrated the boat-to-boat inversions of the addend. In addition, 5b revealed remarkable thermal stability in comparison with the reported [4 + 2] cycloadduct of pentamethylcyclopentadiene and La@C82 (6). These findings demonstrate the utility of sultines to afford thermodynamically stable endohedral metallofullerene derivatives for the use in material science.

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