ChemInform Abstract: Unusual Synthesis of New Glycine Antagonists via Sequential Aldol Condensation-Lactonization-Elimination Reaction.

ChemInform ◽  
2010 ◽  
Vol 29 (44) ◽  
pp. no-no
Author(s):  
S. A. GIACOBBE ◽  
D. BARALDI ◽  
R. DI FABIO
Keyword(s):  
Aldol Condensation ◽  
Elimination Reaction

Characterization of Chemical Impurities in Glutaraldehyde

1975 ◽  
Vol 33 ◽  
pp. 620-621
Author(s):  
B. J. Grenon ◽  
A. J. Tousimis
Keyword(s):  
Glutaric Acid ◽  
Spectroscopic Analysis ◽  
Aldol Condensation ◽  
Condensation Product ◽  
Amorphous Solid ◽  
Water Soluble ◽  
Impurity Component ◽  
Chemical Impurities ◽  
Soluble Liquid

Ever since the introduction of glutaraldehyde as a fixative in electron microscopy of biological specimens, the identification of impurities and consequently their effects on biologic ultrastructure have been under investigation. Several reports postulate that the impurities of glutaraldehyde, used as a fixative, are glutaric acid, glutaraldehyde polymer, acrolein and glutaraldoxime.Analysis of commercially available biological or technical grade glutaraldehyde revealed two major impurity components, none of which has been reported. The first compound is a colorless, water-soluble liquid with a boiling point of 42°C at 16 mm. Utilizing Nuclear Magnetic Resonance (NMR) spectroscopic analysis, this compound has been identified to be — dihydro-2-ethoxy 2H-pyran. This impurity component of the glutaraldehyde biological or technical grades has an UV absorption peak at 235nm. The second compound is a white amorphous solid which is insoluble in water and has a melting point of 80-82°C. Initial chemical analysis indicates that this compound is an aldol condensation product(s) of glutaraldehyde.

Unexpected isolation of a cyclohexenone derivative

2019 ◽  
Vol 74 (11-12) ◽  
pp. 819-824
Author(s):  
Jürgen Voss ◽  
Rüdiger Röske ◽  
Gunnar Ehrlich ◽  
Gunadi Adiwidjaja
Keyword(s):  
Structure Determination ◽  
Aldol Condensation ◽  
Knoevenagel Reaction ◽  
X Ray

AbstractKnoevenagel reaction of pivaloylacetone with formaldehyde and subsequent aldol condensation ends up with 3-methyl-4,6-dipivaloylcyclohex-2-enone. The structure of the product is proved by an X-ray structure determination.

scholarly journals Studies on the Elimination Reaction of d-Amino Acid Oxidase with α-Amino-β-chlorobutyrate

1973 ◽  
Vol 248 (6) ◽  
pp. 1946-1955 ◽  
Author(s):  
Christopher T. Walsh ◽  
Elizabeth Krodel ◽  
Vincent Massey ◽  
Robert H. Abeles
Keyword(s):  
Amino Acid ◽  
Acid Oxidase ◽  
Elimination Reaction ◽  
Amino Acid Oxidase

scholarly journals Nonanal Sensor Fabrication Using Aldol Condensation Reaction Inside Alkali-Resistant Porous Glass

2021 ◽  
pp. 1-1
Author(s):  
Masato Tsujiguchi ◽  
Takashi Aitoku ◽  
Hironori Takase ◽  
Yasuko Yamada Maru
Keyword(s):  
Porous Glass ◽  
Aldol Condensation ◽  
Condensation Reaction ◽  
Sensor Fabrication
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