ChemInform Abstract: DMD Oxidation of in-situ-Generated σH Adducts Derived from Nitroarenes and the Carbanion of 2-Phenylpropionitrile to Phenols: The First Direct Substitution of a Nitro by a Hydroxy Group.

ChemInform ◽  
2010 ◽  
Vol 29 (44) ◽  
pp. no-no
Author(s):  
W. ADAM ◽  
M. MAKOSZA ◽  
K. STALINSKI ◽  
C.-G. ZHAO
Keyword(s):  
Hydroxy Group ◽  
Direct Substitution

Direct Substitution of the Hydroxy Group in Alcohols with Silyl Nucleophiles Catalyzed by Indium Trichloride.

ChemInform ◽  
2004 ◽  
Vol 35 (27) ◽  
Author(s):  
Makoto Yasuda ◽  
Takahiro Saito ◽  
Masako Ueba ◽  
Akio Baba
Keyword(s):  
Hydroxy Group ◽  
Direct Substitution

scholarly journals Direct substitution of the hydroxy group with highly functionalized nitrogen nucleophiles catalyzed by Au(iii)

2011 ◽  
Vol 47 (29) ◽  
pp. 8322 ◽  
Author(s):  
Takashi Ohshima ◽  
Yasuhito Nakahara ◽  
Junji Ipposhi ◽  
Yoshiki Miyamoto ◽  
Kazushi Mashima
Keyword(s):  
Hydroxy Group ◽  
Direct Substitution ◽  
Nitrogen Nucleophiles

Revision of the structure of 3-methoxy-14α-hydroxy-D-homo-1,3,5-(10)-estratrien-17a-one. A simple 1H NMR method for the determination of configuration of hydroxy group in position 5 and/or 14 of the D-homo-steroid skeleton

1991 ◽  
Vol 56 (7) ◽  
pp. 1512-1524 ◽  
Author(s):  
Miloš Buděšínský ◽  
Alexander Kasal ◽  
Želimír Procházka ◽  
Huynh Kim Thoa ◽  
Soňa Vašíčková ◽  
...  
Keyword(s):  
Hydroxy Group ◽  
Chemical Shifts ◽  
Cotton Effect ◽  
Hydroxyl Group ◽  
H Nmr ◽  
Nmr Method ◽  
Synthetic Models ◽  
Steroid Skeleton

Eignerova and Prochazka found in 1974 the Cotton effect value for 3-methoxy-14α-hydroxy-D-homo-1,3,5(10)-estratrien-17a-one (Ia) to be Δε – 2.76.Calculation of the Δε value for this compound led, however, to a substantially lower value, which suggested the hypothesis that the compound was in fact rather an epimer with the hydroxy group in position 14β. This hypothesis was studied by means of 1H NMR spectra of synthetic models, using the changes of the chemical shifts of angular methyls, induced by in situ acylation of the angular hydroxyl with an α- or β-configuration with trichloroacetyl isocyanate (TAI). The observed TAI-acylation shifts on model compounds indicated the structure Ib with a 14b-configuration of the hydroxyl group. Indenpendent proof has been given by the synthesis of both 14-hydroxy epimers, Ia and Ib. A simple 1H NMR method is proposed for the determination of configuration of the hydroxyl in position 5 or 14 of D-homo-steroid skeleton.

Direct Substitution of Hydroxy Group of π-Activated Alcohols with Electron-Deficient Amines Using Re2O7 Catalyst

2012 ◽  
Vol 77 (13) ◽  
pp. 5577-5583 ◽  
Author(s):  
Braja Gopal Das ◽  
Rajender Nallagonda ◽  
Prasanta Ghorai
Keyword(s):  
Hydroxy Group ◽  
Direct Substitution
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