ChemInform Abstract: Convenient Route to γ-Nitro-α-amino Acids: Conjugate Addition of Nitroalkanes to Dehydroalanine Derivatives.

ChemInform ◽  
2010 ◽  
Vol 29 (30) ◽  
pp. no-no
Author(s):  
M. J. CROSSLEY ◽  
Y. M. FUNG ◽  
J. J. POTTER ◽  
A. W. STAMFORD
Keyword(s):  
Amino Acids ◽  
Conjugate Addition ◽  
Convenient Route

A Convenient Route to O-Glycosyl Lactates via Conjugate Addition to 2-Nitroglycals: Ring Closure to Novel Pyrano[2.3-b][1,4]-oxazines

Synthesis ◽  
2003 ◽  
Vol 2004 (01) ◽  
pp. 53-58
Author(s):  
Richard Schmidt ◽  
Ahmed Khodair ◽  
Kandasamy Pachamuthu
Keyword(s):  
Conjugate Addition ◽  
Ring Closure ◽  
Convenient Route

scholarly journals Michael Addition of Imidazole to α, β -Unsaturated Carbonyl/Cyano Compound

2018 ◽  
Vol 5 (1) ◽  
pp. 18-31
Author(s):  
Seetaram Mohapatra ◽  
Nilofar Baral ◽  
Nilima Priyadarsini Mishra ◽  
Pravati Panda ◽  
Sabita Nayak
Keyword(s):  
Organic Chemistry ◽  
Amino Acids ◽  
Anticancer Agents ◽  
Michael Addition ◽  
Addition Reaction ◽  
Bond Formation ◽  
Conjugate Addition ◽  
Michael Addition Reaction ◽  
Cyano Compounds ◽  
Nitrogen Bond

Introduction: Aza-Michael addition is an important reaction for carbon-nitrogen bond formation in synthetic organic chemistry. Expalantion: Conjugate addition of imidazole to α,β-unsaturated carbonyl/cyano compounds provides significant numbers of the biologically and synthetically interesting products, such as β-amino acids and β-lactams, which have attracted great attention for their use as key intermediates of anticancer agents, antibiotics and other drugs. Conclusion: This review addresses most significant method for the synthesis of N-substituted imidazole derivatives following Michael addition reaction of imidazole to α,β-unsaturated carbonyl/cyano compounds using ionic liquid/base/acid/enzyme as catalysts from year 2007-2017.

Asymmetric synthesis of cyclic β-amino acids and cyclic amines via sequential diastereoselective conjugate addition and ring closing metathesis

Tetrahedron ◽  
2003 ◽  
Vol 59 (18) ◽  
pp. 3253-3265 ◽  
Author(s):  
Ann M Chippindale ◽  
Stephen G Davies ◽  
Keiji Iwamoto ◽  
Richard M Parkin ◽  
Christian A.P Smethurst ◽  
...  
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Conjugate Addition ◽  
Ring Closing Metathesis ◽  
Cyclic Amines

Amino Acid Catalyzed Conjugate Addition of Thiol to Dienone

2013 ◽  
Vol 834-836 ◽  
pp. 450-453
Author(s):  
Han Feng Cui ◽  
Yan Lin ◽  
Hao Fan ◽  
Li De Yu ◽  
Ping Nan Wan
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Room Temperature ◽  
Addition Product ◽  
Conjugate Addition ◽  
Acid Catalyzed

Double conjugate addition of thiols with dienones was catalyzed by amino acids at room temperature in methanol, to afford the corresponding addition product in good to excellent yields.

Sign in / Sign up

Export Citation Format

Share Document