ChemInform Abstract: Carbonic Anhydrase Inhibitors. Part 43. Schiff Bases Derived from Aromatic Sulfonamides: Towards More Specific Inhibitors for Membrane- Bound versus Cytosolic Isozymes.

C. T. SUPURAN; A. SCOZZAFAVA; A. POPESCU; R. BOBES-TUREAC; A. BANCIU; A. CREANGA; G. BOBES-TUREAC; M. D. BANCIU

doi:10.1002/chin.199743274

ChemInform Abstract: Carbonic Anhydrase Inhibitors. Part 43. Schiff Bases Derived from Aromatic Sulfonamides: Towards More Specific Inhibitors for Membrane- Bound versus Cytosolic Isozymes.

ChemInform ◽

10.1002/chin.199743274 ◽

2010 ◽

Vol 28 (43) ◽

pp. no-no

Author(s):

C. T. SUPURAN ◽

A. SCOZZAFAVA ◽

A. POPESCU ◽

R. BOBES-TUREAC ◽

A. BANCIU ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Schiff Bases ◽

Carbonic Anhydrase Inhibitors ◽

Membrane Bound ◽

Specific Inhibitors

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Carbonic anhydrase inhibitors. Part 43. Schiff bases derived from aromatic sulfonamides: towards more specific inhibitors for membrane-bound versus cytosolic isozymes

European Journal of Medicinal Chemistry ◽

10.1016/s0223-5234(97)81681-9 ◽

1997 ◽

Vol 32 (5) ◽

pp. 445-452 ◽

Cited By ~ 50

Author(s):

CT Supuran ◽

A Scozzafava ◽

A Popescu ◽

R Bobes-Tureac ◽

A Banciu ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Schiff Bases ◽

Carbonic Anhydrase Inhibitors ◽

Membrane Bound ◽

Specific Inhibitors

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Carbonic anhydrase inhibitors. Part 35. Synthesis of Schiff bases derived from sulfanilamide and aromatic aldehydes: the first inhibitors with equally high affinity towards cytosolic and membrane-bound isozymes

European Journal of Medicinal Chemistry ◽

10.1016/0223-5234(96)85163-4 ◽

1996 ◽

Vol 31 (6) ◽

pp. 431-438 ◽

Cited By ~ 96

Author(s):

CT Supuran ◽

A Nicolae ◽

A Popescu

Keyword(s):

Carbonic Anhydrase ◽

Schiff Bases ◽

Aromatic Aldehydes ◽

Carbonic Anhydrase Inhibitors ◽

High Affinity ◽

Membrane Bound

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ChemInform Abstract: Carbonic Anhydrase Inhibitors. Part 35. Synthesis of Schiff Bases Derived from Sulfanilamide and Aromatic Aldehydes: The First Inhibitors with Equally High Affinity Towards Cytosolic and Membrane- Bound Isozymes.

ChemInform ◽

10.1002/chin.199638121 ◽

2010 ◽

Vol 27 (38) ◽

pp. no-no

Author(s):

C. T. SUPURAN ◽

A. NICOLAE ◽

A. POPESCU

Keyword(s):

Carbonic Anhydrase ◽

Schiff Bases ◽

Aromatic Aldehydes ◽

Carbonic Anhydrase Inhibitors ◽

High Affinity ◽

Membrane Bound

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Carbonic Anhydrase Inhibitors: Synthesis of Membrane-Impermeant Low Molecular Weight Sulfonamides Possessing in Vivo Selectivity for the Membrane-Bound versus Cytosolic Isozymes1

Journal of Medicinal Chemistry ◽

10.1021/jm990479+ ◽

2000 ◽

Vol 43 (2) ◽

pp. 292-300 ◽

Cited By ~ 95

Author(s):

Andrea Scozzafava ◽

Fabrizio Briganti ◽

Marc A. Ilies ◽

Claudiu T. Supuran

Keyword(s):

Molecular Weight ◽

Carbonic Anhydrase ◽

Low Molecular Weight ◽

Carbonic Anhydrase Inhibitors ◽

Membrane Bound

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Carbonic anhydrase inhibitors. Part 36. Inhibition of isozymes I and II with Schiff bases derived from chalkones and aromatic/heterocyclic sulfonamides

European Journal of Medicinal Chemistry ◽

10.1016/0223-5234(96)85164-6 ◽

1996 ◽

Vol 31 (6) ◽

pp. 439-447 ◽

Cited By ~ 54

Author(s):

CT Supuran ◽

A Popescu ◽

M Ilisiu ◽

A Costandache ◽

MD Banciu

Keyword(s):

Carbonic Anhydrase ◽

Schiff Bases ◽

Carbonic Anhydrase Inhibitors ◽

Aromatic Heterocyclic

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Heterocyclic periphery in the design of carbonic anhydrase inhibitors: 1,2,4-Oxadiazol-5-yl benzenesulfonamides as potent and selective inhibitors of cytosolic h CA II and membrane-bound h CA IX isoforms

Bioorganic Chemistry ◽

10.1016/j.bioorg.2017.10.005 ◽

2018 ◽

Vol 76 ◽

pp. 88-97 ◽

Cited By ~ 30

Author(s):

Mikhail Krasavin ◽

Anton Shetnev ◽

Tatyana Sharonova ◽

Sergey Baykov ◽

Tiziano Tuccinardi ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Selective Inhibitors ◽

Carbonic Anhydrase Inhibitors ◽

Ca Ix ◽

Membrane Bound

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Carbonic Anhydrase Inhibitors: Synthesis of Schiff Bases of Hydroxybenzaldehydes with Aromatic Sulfonamides and Their Reactions with Arylsulfonyl Isocyanates

Journal of Enzyme Inhibition ◽

10.3109/14756360009040708 ◽

2000 ◽

Vol 15 (6) ◽

pp. 533-546 ◽

Cited By ~ 20

Author(s):

Andrea Scozzafava ◽

Mircea D. Banciu ◽

Angela Popescu ◽

Claudiu T. Supuran

Keyword(s):

Carbonic Anhydrase ◽

Schiff Bases ◽

Carbonic Anhydrase Inhibitors

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Carbonic Anhydrase Inhibitors. V: Pyrylium Salts in the Synthesis of Isozyme-Specific Inhibitors

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600810726 ◽

1992 ◽

Vol 81 (7) ◽

pp. 716-719 ◽

Cited By ~ 31

Author(s):

Claudiu T. Supuran ◽

Gheorghe Manole ◽

Antonie Dinculescu ◽

Ana Schiketanz ◽

Mircea D. Gheorghiu ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Pyrylium Salts ◽

Specific Inhibitors

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Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2004.09.063 ◽

2004 ◽

Vol 14 (23) ◽

pp. 5769-5773 ◽

Cited By ~ 25

Author(s):

Alessio Innocenti ◽

Michael A. Firnges ◽

Jochen Antel ◽

Michael Wurl ◽

Andrea Scozzafava ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Membrane Bound

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Carbonic Anhydrase Inhibitors: Synthesis of Sulfonamides Incorporating 2, 4, 6–Trisubstituted-Pyridinium-Ethylcarboxamido Moieties Possessing Membrane-Impermeability and in Vivo Selectivity for the Membrane-Bound (CA IV) Versus the Cytosolic (CA I and CA II) Isozymes

Journal of Enzyme Inhibition ◽

10.1080/14756360009040695 ◽

2000 ◽

Vol 15 (4) ◽

pp. 381-401 ◽

Cited By ~ 32

Author(s):

Claudiu T. Supuran ◽

Andrea Scozzafava ◽

Marc A. Ilies ◽

Fabrizio Briganti

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Membrane Bound

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