ChemInform Abstract: Biologically Active Metabolites from Fungi. Part 8. Dihydroisocoumarins from Fungi: Isolation, Structure Elucidation, Circular Dichroism and Biological Activity.

ChemInform ◽  
2010 ◽  
Vol 28 (35) ◽  
pp. no-no
Author(s):  
K. KROHN ◽  
R. BAHRAMSARI ◽  
U. FLOERKE ◽  
K. LUDEWIG ◽  
C. KLICHE-SPORY ◽  
...  
Keyword(s):  
Biological Activity ◽  
Circular Dichroism ◽  
Structure Elucidation ◽  
Biologically Active ◽  
Active Metabolites ◽  
Biologically Active Metabolites ◽  
Circular Dichroïsm

Biologically Active Metabolites from Fungi, 4. Palmarumycins CP1–CP4 fromConiothyrium palmarum: Isolation, Structure Elucidation, and Biological Activity

1994 ◽  
Vol 1994 (11) ◽  
pp. 1093-1097 ◽  
Author(s):  
Karsten Krohn ◽  
Andreas Michel ◽  
Ulrich Flörke ◽  
Hans-Jürgen Aust ◽  
Siegfried Draeger ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structure Elucidation ◽  
Biologically Active ◽  
Active Metabolites ◽  
Biologically Active Metabolites

Biologically Active Metabolites from Fungi, 5. Palmarumycins C1–C16 fromConiothyrium sp.: Isolation, Structure Elucidation, and Biological Activity

1994 ◽  
Vol 1994 (11) ◽  
pp. 1099-1108 ◽  
Author(s):  
Karsten Krohn ◽  
Andreas Michel ◽  
Ulrich Flörke ◽  
Hans-Jürgen Aust ◽  
Siegfried Draeger ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structure Elucidation ◽  
Biologically Active ◽  
Active Metabolites ◽  
Biologically Active Metabolites

scholarly journals Circular dichroism of bradykinin and related peptides

1971 ◽  
Vol 121 (2) ◽  
pp. 179-184 ◽  
Author(s):  
A. H. Brady ◽  
J. W. Ryan ◽  
J. M. Stewart
Keyword(s):  
Biological Activity ◽  
Circular Dichroism ◽  
Amino Acid ◽  
Amino Acid Composition ◽  
Molecular Interactions ◽  
Biologically Active ◽  
Spectral Features ◽  
Active Peptides ◽  
Biologically Active Peptides ◽  
Circular Dichroïsm

1. The circular dichroism of bradykinin and a number of its analogues and homologues was measured over the spectral range 200–300nm. All of the biologically active peptides showed maxima at 220nm and minima at 235nm. The spectra were independent of solvent and temperature. The vibronic transitions of phenylalanyl residues in the 250–280nm range showed no evidence of intra- or inter-molecular interactions. We take this as evidence that bradykinin and its biologically active analogues and homologues exist in solution as disordered chains. 2. None of the analogues with spectra unlike bradykinin possessed biological activity. However, peptides such as retro-bradykinin, des-6-serine-bradykinin, des-1-arginine-bradykinin and des-9-arginine-bradykinin produced spectra like that of bradykinin but were devoid of biological activity. Although we could not identify spectral features that were clearly correlated with biological activity, it appears unlikely that highly ordered peptides of the same amino acid composition as bradykinin would possess bradykinin-like effects.

Dihydroisocoumarins from fungi: Isolation, structure elucidation, circular dichroism and biological activity

1997 ◽  
Vol 45 (2) ◽  
pp. 313-320 ◽  
Author(s):  
Karsten Krohn ◽  
Rahim Bahramsari ◽  
Ulrich Flörke ◽  
Kerstin Ludewig ◽  
Christine Kliche-Spory ◽  
...  
Keyword(s):  
Biological Activity ◽  
Circular Dichroism ◽  
Structure Elucidation ◽  
Circular Dichroïsm
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