ChemInform Abstract: Synthesis of Peptides Using Palladium-Promoted Selective Removal of Allyloxycarbonyl Protecting Groups in Aqueous Medium.

ChemInform ◽  
2010 ◽  
Vol 28 (32) ◽  
pp. no-no
Author(s):  
S. LEMAIRE-AUDOIRE ◽  
M. SAVIGNAC ◽  
E. BLART ◽  
J.-M. BERNARD ◽  
J. P. GENET
Keyword(s):  
Aqueous Medium ◽  
Selective Removal ◽  
Protecting Groups

Synthesis of Peptides Using Palladium Promoted Selective Removal of Allyloxycarbonyl Protecting Groups in Aqueous Medium

1997 ◽  
Vol 38 (17) ◽  
pp. 2955-2958 ◽  
Author(s):  
Sandrine Lemaire-Audoire ◽  
Monique Savignac ◽  
Errol Blart ◽  
Jean-Marie Bernard ◽  
Jean Pierre Genêt
Keyword(s):  
Aqueous Medium ◽  
Selective Removal ◽  
Protecting Groups

scholarly journals Zwitterionic superabsorbent polymer hydrogels for efficient and selective removal of organic dyes

RSC Advances ◽  
2019 ◽  
Vol 9 (32) ◽  
pp. 18565-18577 ◽  
Author(s):  
Tanzil Ur Rehman ◽  
Luqman Ali Shah ◽  
Mansoor Khan ◽  
Muhammad Irfan ◽  
Noor Saeed Khattak
Keyword(s):  
Free Radical ◽  
Aqueous Medium ◽  
Radical Polymerization ◽  
Crystal Violet ◽  
Congo Red ◽  
Organic Dyes ◽  
Selective Removal ◽  
Superabsorbent Polymer ◽  
Polymer Hydrogel ◽  
Polymer Hydrogels

A novel zwitterionic superabsorbent polymer hydrogel [ZI-SAH] was synthesized by free radical polymerization and used for the removal of crystal violet (CV) and congo red (CR) from an aqueous medium.

Deprotective activity of nanosized globular partially quaternized poly(tertiary amine)s in peptide synthesis

e-Polymers ◽  
2002 ◽  
Vol 2 (1) ◽  
Author(s):  
Pascal Chapon ◽  
Jean Coudane ◽  
Henri Garreau ◽  
Michel Vert ◽  
Jean Alain Ferhentz ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Aqueous Medium ◽  
Room Temperature ◽  
Heterogeneous Systems ◽  
Protecting Groups ◽  
Hydrophobic Core ◽  
Poly Ethylene Glycol ◽  
Solid Supports ◽  
Spacer Arm ◽  
Poly Ethylene

AbstractBifunctional polybases of the partially quaternized poly[thio-1-(N,Ndiethylaminomethyl) ethylene] type (Q(PTDAE),X, with X = percentage of N-quaternization) are able to catalyze various reactions including lipophilic reagents temporarily entrapped in the hydrophobic core of the globules. In this contribution it is shown that benzyloxycarbonyl (Z) and fluoromethyloxycarbonyl (Fmoc) protecting groups of peptides are cleaved at room temperature in a few minutes in an aqueous medium at pH 7,4. Deprotection was also effective when peptides were attached to solid supports of the Merrifield type provided a hydrophilic spacer arm of the poly(ethylene glycol)-type was inserted between beads and the built up peptide moieties. However, unhooking was observed when the hydrophilic spacerpeptide bond was an ester but not when it was of the amide type. The work shows that Q(PTDAE),X globules exhibit enzyme-like activity in a homogeneous aqueous medium and in heterogeneous systems as well.

scholarly journals Studies on peptides. 69. Selective removal of acid labile .ALPHA.-amino protecting groups with dilute sulfonic acids.

1977 ◽  
Vol 25 (4) ◽  
pp. 740-747 ◽  
Author(s):  
HARUAKI YAJIMA ◽  
HIROSHI OGAWA ◽  
NOBUTAKA FUJII ◽  
SUSUMU FUNAKOSHI
Keyword(s):  
Selective Removal ◽  
Protecting Groups ◽  
Sulfonic Acids ◽  
Acid Labile

Über 5-Hydroxymethyl-cytidin und 5-Hydroxymethyl-cytosin-N-3-β-D-glucopyranosid sowie über reaktionsfähige Vorstufen

1966 ◽  
Vol 21 (10) ◽  
pp. 942-952 ◽  
Author(s):  
Reinhard Brossmer ◽  
Erich Röhm
Keyword(s):  
Hydrochloric Acid ◽  
Benzyl Alcohol ◽  
Catalytic Hydrogenation ◽  
Sodium Methoxide ◽  
Room Temperature ◽  
Selective Removal ◽  
Protecting Groups ◽  
Hydroxymethyl Cytosine ◽  
Analogous Manner ◽  
Synthetic Intermediates

5-Benzyloxymethyl-NNH2-benzoyl-cytosine (4) is formed from 5-hydroxymethyl-cytosine (1) in 80% yield by benzylation and subsequent benzoylation. The benzylation readily takes place with benzyl alcohol and catalytic amounts of hydrochloric acid in tetrahydrothiophen-1.1-dioxide as solvent. — 4 is quantitatively converted in pyridine at room temperature to a toluene soluble mercury (II) salt 5.5 condenses easily with 2.3.5-tribenzoyl-D-ribofuranosyl chloride to give the β-nucleoside 6, no a-anomer being found. — The removal of all protecting groups by catalytic hydrogenation and treatment with sodium methoxide or ammonia leads to cristalline 5-hydroxymethyl cytidine 10 (ca. 60% yields based on 1). — In an analogous manner N-3-β-D-glucosyl-5-hydroxymethyl-cytosine 15 is prepared. — Selective removal of certain of the protecting groups in 6 and 11 yields potentially valuable synthetic intermediates.

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