ChemInform Abstract: Chiral Lewis Acids-Controlled Synthesis. Enantioselective Synthesis of Both Diastereomers Including the α-Alkoxy-α-methyl-β- hydroxy Units.

ChemInform ◽  
2010 ◽  
Vol 26 (46) ◽  
pp. no-no
Author(s):  
S. KOBAYASHI ◽  
M. HORIBE ◽  
M. MATSUMURA
Author(s):  
Xin-Ming Xu ◽  
Ming Xie ◽  
Jiazhu Li ◽  
Mei-Xiang Wang

An exquisite Pybox/Cu(OTf)2-catalyzed asymmetric tandem reaction of tertiary enamides was developed, which enabled the expeditious synthesis of indolizino[8,7-b]indole derivatives in high yield, excellent enantioselectivity and diastereoselectivity.


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